BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 25762636)

  • 1. A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide.
    Pojo M; Gonçalves CS; Xavier-Magalhães A; Oliveira AI; Gonçalves T; Correia S; Rodrigues AJ; Costa S; Pinto L; Pinto AA; Lopes JM; Reis RM; Rocha M; Sousa N; Costa BM
    Oncotarget; 2015 Apr; 6(10):7657-74. PubMed ID: 25762636
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature.
    Gaspar N; Marshall L; Perryman L; Bax DA; Little SE; Viana-Pereira M; Sharp SY; Vassal G; Pearson AD; Reis RM; Hargrave D; Workman P; Jones C
    Cancer Res; 2010 Nov; 70(22):9243-52. PubMed ID: 20935218
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma.
    Costa BM; Smith JS; Chen Y; Chen J; Phillips HS; Aldape KD; Zardo G; Nigro J; James CD; Fridlyand J; Reis RM; Costello JF
    Cancer Res; 2010 Jan; 70(2):453-62. PubMed ID: 20068170
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression.
    Le Calvé B; Rynkowski M; Le Mercier M; Bruyère C; Lonez C; Gras T; Haibe-Kains B; Bontempi G; Decaestecker C; Ruysschaert JM; Kiss R; Lefranc F
    Neoplasia; 2010 Sep; 12(9):727-39. PubMed ID: 20824049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas.
    Li S; Zeng A; Hu Q; Yan W; Liu Y; You Y
    Neuro Oncol; 2017 Jan; 19(1):55-65. PubMed ID: 27471108
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis.
    Gonçalves CS; Xavier-Magalhães A; Martins EP; Pinto AA; Pires MM; Pinheiro C; Reis RM; Sousa N; Costa BM
    Mol Oncol; 2020 Jun; 14(6):1224-1241. PubMed ID: 31923345
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis.
    Miao W; Liu X; Wang H; Fan Y; Lian S; Yang X; Wang X; Guo G; Li Q; Wang S
    Mol Med Rep; 2015 Jun; 11(6):4165-73. PubMed ID: 25625235
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells.
    Mazor G; Levin L; Picard D; Ahmadov U; Carén H; Borkhardt A; Reifenberger G; Leprivier G; Remke M; Rotblat B
    Cell Death Dis; 2019 Mar; 10(3):246. PubMed ID: 30867410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells.
    Zhang F; Liu R; Zhang H; Liu C; Liu C; Lu Y
    BMC Cancer; 2020 Jul; 20(1):673. PubMed ID: 32682409
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nuclear factor I A promotes temozolomide resistance in glioblastoma via activation of nuclear factor κB pathway.
    Yu X; Wang M; Zuo J; Wahafu A; Mao P; Li R; Wu W; Xie W; Wang J
    Life Sci; 2019 Nov; 236():116917. PubMed ID: 31614149
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.
    Golubovskaya VM; Huang G; Ho B; Yemma M; Morrison CD; Lee J; Eliceiri BP; Cance WG
    Mol Cancer Ther; 2013 Feb; 12(2):162-72. PubMed ID: 23243059
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metformin treatment reduces temozolomide resistance of glioblastoma cells.
    Yang SH; Li S; Lu G; Xue H; Kim DH; Zhu JJ; Liu Y
    Oncotarget; 2016 Nov; 7(48):78787-78803. PubMed ID: 27791206
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.
    Hiddingh L; Tannous BA; Teng J; Tops B; Jeuken J; Hulleman E; Boots-Sprenger SH; Vandertop WP; Noske DP; Kaspers GJ; Wesseling P; Wurdinger T
    Oncotarget; 2014 Jan; 5(2):363-74. PubMed ID: 24495907
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interference with PSMB4 Expression Exerts an Anti-Tumor Effect by Decreasing the Invasion and Proliferation of Human Glioblastoma Cells.
    Cheng YC; Tsai WC; Sung YC; Chang HH; Chen Y
    Cell Physiol Biochem; 2018; 45(2):819-831. PubMed ID: 29414809
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytoplasmic TRADD confers a worse prognosis in glioblastoma.
    Chakraborty S; Li L; Tang H; Xie Y; Puliyappadamba VT; Raisanen J; Burma S; Boothman DA; Cochran B; Wu J; Habib AA
    Neoplasia; 2013 Aug; 15(8):888-97. PubMed ID: 23908590
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Annexin A5 promotes invasion and chemoresistance to temozolomide in glioblastoma multiforme cells.
    Wu L; Yang L; Xiong Y; Guo H; Shen X; Cheng Z; Zhang Y; Gao Z; Zhu X
    Tumour Biol; 2014 Dec; 35(12):12327-37. PubMed ID: 25245332
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival.
    Luchman HA; Stechishin OD; Nguyen SA; Lun XQ; Cairncross JG; Weiss S
    Clin Cancer Res; 2014 Nov; 20(22):5756-67. PubMed ID: 25316808
    [TBL] [Abstract][Full Text] [Related]  

  • 18. mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.
    Garros-Regulez L; Aldaz P; Arrizabalaga O; Moncho-Amor V; Carrasco-Garcia E; Manterola L; Moreno-Cugnon L; Barrena C; Villanua J; Ruiz I; Pollard S; Lovell-Badge R; Sampron N; Garcia I; Matheu A
    Expert Opin Ther Targets; 2016; 20(4):393-405. PubMed ID: 26878385
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IKBKE enhances TMZ-chemoresistance through upregulation of MGMT expression in glioblastoma.
    Guo G; Sun Y; Hong R; Xiong J; Lu Y; Liu Y; Lu J; Zhang Z; Guo C; Nan Y; Huang Q
    Clin Transl Oncol; 2020 Aug; 22(8):1252-1262. PubMed ID: 31865606
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis.
    Yang CH; Wang Y; Sims M; Cai C; He P; Yue J; Cheng J; Boop FA; Pfeffer SR; Pfeffer LM
    Oncotarget; 2016 Dec; 7(51):84017-84029. PubMed ID: 27705947
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.