BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 25762722)

  • 1. Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells.
    Barbour SE; Nguyen PT; Park M; Emani B; Lei X; Kambalapalli M; Shultz JC; Wijesinghe D; Chalfant CE; Ramanadham S
    J Biol Chem; 2015 Apr; 290(17):11021-31. PubMed ID: 25762722
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.
    Lei X; Zhang S; Bohrer A; Bao S; Song H; Ramanadham S
    Biochemistry; 2007 Sep; 46(35):10170-85. PubMed ID: 17685585
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genetic modulation of islet β-cell iPLA₂β expression provides evidence for its impact on β-cell apoptosis and autophagy.
    Lei X; Bone RN; Ali T; Wohltmann M; Gai Y; Goodwin KJ; Bohrer AE; Turk J; Ramanadham S
    Islets; 2013; 5(1):29-44. PubMed ID: 23411472
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evidence of contribution of iPLA2β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2β in T1D development.
    Lei X; Bone RN; Ali T; Zhang S; Bohrer A; Tse HM; Bidasee KR; Ramanadham S
    Endocrinology; 2014 Sep; 155(9):3352-64. PubMed ID: 25004092
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Proto-oncogene PKCι regulates the alternative splicing of Bcl-x pre-mRNA.
    Shultz JC; Vu N; Shultz MD; Mba MU; Shapiro BA; Chalfant CE
    Mol Cancer Res; 2012 May; 10(5):660-9. PubMed ID: 22522453
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetes.
    Ali T; Kokotos G; Magrioti V; Bone RN; Mobley JA; Hancock W; Ramanadham S
    PLoS One; 2013; 8(8):e71748. PubMed ID: 23977134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Group VIA PLA2 (iPLA2β) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet β-cell signaling.
    Song H; Wohltmann M; Tan M; Bao S; Ladenson JH; Turk J
    J Biol Chem; 2012 Feb; 287(8):5528-41. PubMed ID: 22194610
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Group VIA phospholipase A2 mitigates palmitate-induced β-cell mitochondrial injury and apoptosis.
    Song H; Wohltmann M; Tan M; Ladenson JH; Turk J
    J Biol Chem; 2014 May; 289(20):14194-210. PubMed ID: 24648512
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis.
    Lei X; Zhang S; Bohrer A; Ramanadham S
    J Biol Chem; 2008 Dec; 283(50):34819-32. PubMed ID: 18936091
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A link between endoplasmic reticulum stress-induced β-cell apoptosis and the group VIA Ca2+-independent phospholipase A2 (iPLA2β).
    Lei X; Zhang S; Emani B; Barbour SE; Ramanadham S
    Diabetes Obes Metab; 2010 Oct; 12 Suppl 2(0 2):93-8. PubMed ID: 21029305
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alterations in β-Cell Sphingolipid Profile Associated with ER Stress and iPLA
    Ali T; Lei X; Barbour SE; Koizumi A; Chalfant CE; Ramanadham S
    Molecules; 2021 Oct; 26(21):. PubMed ID: 34770770
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SAP155 Binds to ceramide-responsive RNA cis-element 1 and regulates the alternative 5' splice site selection of Bcl-x pre-mRNA.
    Massiello A; Roesser JR; Chalfant CE
    FASEB J; 2006 Aug; 20(10):1680-2. PubMed ID: 16790528
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA
    Li J; Du H; Zhang M; Zhang Z; Teng F; Zhao Y; Zhang W; Yu Y; Feng L; Cui X; Zhang M; Lu T; Guan F; Chen L
    Int J Biol Sci; 2019; 15(7):1533-1545. PubMed ID: 31337982
    [No Abstract]   [Full Text] [Related]  

  • 14. Metabolic Effects of Selective Deletion of Group VIA Phospholipase A
    Turk J; Song H; Wohltmann M; Frankfater C; Lei X; Ramanadham S
    Biomolecules; 2020 Oct; 10(10):. PubMed ID: 33080873
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of two RNA cis-elements that function to regulate the 5' splice site selection of Bcl-x pre-mRNA in response to ceramide.
    Massiello A; Salas A; Pinkerman RL; Roddy P; Roesser JR; Chalfant CE
    J Biol Chem; 2004 Apr; 279(16):15799-804. PubMed ID: 14734550
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of 5' splice-sites through multiple exonic motifs by hnRNP L.
    Loh TJ; Choi N; Moon H; Jang HN; Liu Y; Zhou J; Zheng X; Shen H
    Biochim Biophys Acta Gene Regul Mech; 2017 Mar; 1860(3):363-373. PubMed ID: 28119102
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta.
    Ramanadham S; Hsu FF; Zhang S; Jin C; Bohrer A; Song H; Bao S; Ma Z; Turk J
    Biochemistry; 2004 Feb; 43(4):918-30. PubMed ID: 14744135
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.
    Bone RN; Gai Y; Magrioti V; Kokotou MG; Ali T; Lei X; Tse HM; Kokotos G; Ramanadham S
    Diabetes; 2015 Feb; 64(2):541-54. PubMed ID: 25213337
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of stable suppression of Group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells.
    Bao S; Bohrer A; Ramanadham S; Jin W; Zhang S; Turk J
    J Biol Chem; 2006 Jan; 281(1):187-98. PubMed ID: 16286468
    [TBL] [Abstract][Full Text] [Related]  

  • 20. iPLA
    Jin T; Lin J; Gong Y; Bi X; Hu S; Lv Q; Chen J; Li X; Chen J; Zhang W; Wang M; Fu G
    Cells; 2021 Jun; 10(6):. PubMed ID: 34207793
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.