777 related articles for article (PubMed ID: 25762741)
1. Degradation of SAMHD1 by Vpx Is Independent of Uncoating.
Jáuregui P; Logue EC; Schultz ML; Fung S; Landau NR
J Virol; 2015 May; 89(10):5701-13. PubMed ID: 25762741
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly.
Wang H; Guo H; Su J; Rui Y; Zheng W; Gao W; Zhang W; Li Z; Liu G; Markham RB; Wei W; Yu XF
J Virol; 2017 May; 91(9):. PubMed ID: 28202763
[TBL] [Abstract][Full Text] [Related]
3. HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.
Ahn J; Hao C; Yan J; DeLucia M; Mehrens J; Wang C; Gronenborn AM; Skowronski J
J Biol Chem; 2012 Apr; 287(15):12550-8. PubMed ID: 22362772
[TBL] [Abstract][Full Text] [Related]
4. A novel DCAF1-binding motif required for Vpx-mediated degradation of nuclear SAMHD1 and Vpr-induced G2 arrest.
Wei W; Guo H; Han X; Liu X; Zhou X; Zhang W; Yu XF
Cell Microbiol; 2012 Nov; 14(11):1745-56. PubMed ID: 22776683
[TBL] [Abstract][Full Text] [Related]
5. Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.
Fregoso OI; Ahn J; Wang C; Mehrens J; Skowronski J; Emerman M
PLoS Pathog; 2013; 9(7):e1003496. PubMed ID: 23874202
[TBL] [Abstract][Full Text] [Related]
6. The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus.
Hofmann H; Logue EC; Bloch N; Daddacha W; Polsky SB; Schultz ML; Kim B; Landau NR
J Virol; 2012 Dec; 86(23):12552-60. PubMed ID: 22973040
[TBL] [Abstract][Full Text] [Related]
7. Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac.
Brandariz-Nuñez A; Valle-Casuso JC; White TE; Laguette N; Benkirane M; Brojatsch J; Diaz-Griffero F
Retrovirology; 2012 Jun; 9():49. PubMed ID: 22691373
[TBL] [Abstract][Full Text] [Related]
8. Identification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradation.
Guo H; Wei W; Wei Z; Liu X; Evans SL; Yang W; Wang H; Guo Y; Zhao K; Zhou JY; Yu XF
PLoS One; 2013; 8(7):e66201. PubMed ID: 23874389
[TBL] [Abstract][Full Text] [Related]
9. Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.
Baldauf HM; Stegmann L; Schwarz SM; Ambiel I; Trotard M; Martin M; Burggraf M; Lenzi GM; Lejk H; Pan X; Fregoso OI; Lim ES; Abraham L; Nguyen LA; Rutsch F; König R; Kim B; Emerman M; Fackler OT; Keppler OT
Proc Natl Acad Sci U S A; 2017 Mar; 114(10):2729-2734. PubMed ID: 28228523
[TBL] [Abstract][Full Text] [Related]
10. Interference with SAMHD1 Restores Late Gene Expression of Modified Vaccinia Virus Ankara in Human Dendritic Cells and Abrogates Type I Interferon Expression.
Sliva K; Martin J; von Rhein C; Herrmann T; Weyrich A; Toda M; Schnierle BS
J Virol; 2019 Nov; 93(22):. PubMed ID: 31462561
[TBL] [Abstract][Full Text] [Related]
11. HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation.
DeLucia M; Mehrens J; Wu Y; Ahn J
J Biol Chem; 2013 Jun; 288(26):19116-26. PubMed ID: 23677995
[TBL] [Abstract][Full Text] [Related]
12. Structural basis of lentiviral subversion of a cellular protein degradation pathway.
Schwefel D; Groom HC; Boucherit VC; Christodoulou E; Walker PA; Stoye JP; Bishop KN; Taylor IA
Nature; 2014 Jan; 505(7482):234-8. PubMed ID: 24336198
[TBL] [Abstract][Full Text] [Related]
13. Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
Wu Y; Koharudin LMI; Mehrens J; DeLucia M; Byeon CH; Byeon IL; Calero G; Ahn J; Gronenborn AM
J Biol Chem; 2015 Jul; 290(29):17935-17945. PubMed ID: 26045556
[TBL] [Abstract][Full Text] [Related]
14. The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T Cells.
Shingai M; Welbourn S; Brenchley JM; Acharya P; Miyagi E; Plishka RJ; Buckler-White A; Kwong PD; Nishimura Y; Strebel K; Martin MA
PLoS Pathog; 2015 May; 11(5):e1004928. PubMed ID: 25996507
[TBL] [Abstract][Full Text] [Related]
15. HIV-2 Depletes CD4 T Cells through Pyroptosis despite Vpx-Dependent Degradation of SAMHD1.
Luo X; Herzig E; Doitsh G; Grimmett ZW; Muñoz-Arias I; Greene WC
J Virol; 2019 Dec; 93(24):. PubMed ID: 31578293
[TBL] [Abstract][Full Text] [Related]
16. HD domain of SAMHD1 influences Vpx-induced degradation at a post-interaction step.
Kang J; Hou J; Zhao K; Yu XF; Du J
Biochem Biophys Res Commun; 2016 Feb; 470(3):690-696. PubMed ID: 26779819
[TBL] [Abstract][Full Text] [Related]
17. Functional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.
Mahalingam S; Van Tine B; Santiago ML; Gao F; Shaw GM; Hahn BH
J Virol; 2001 Jan; 75(1):362-74. PubMed ID: 11119605
[TBL] [Abstract][Full Text] [Related]
18. Host SAMHD1 protein restricts endogenous reverse transcription of HIV-1 in nondividing macrophages.
Mahboubi B; Gavegnano C; Kim DH; Schinazi RF; Kim B
Retrovirology; 2018 Oct; 15(1):69. PubMed ID: 30316304
[TBL] [Abstract][Full Text] [Related]
19. Characterization of the interactions between SIVrcm Vpx and red-capped mangabey SAMHD1.
Li J; Xu F; Hu S; Zhou J; Mei S; Zhao X; Cen S; Jin Q; Liang C; Guo F
Biochem J; 2015 Jun; 468(2):303-13. PubMed ID: 25791246
[TBL] [Abstract][Full Text] [Related]
20. Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complex.
Sharifi HJ; Furuya AK; Jellinger RM; Nekorchuk MD; de Noronha CM
J Virol; 2014 Jun; 88(12):6944-58. PubMed ID: 24719410
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
