848 related articles for article (PubMed ID: 25765079)
1. Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer's disease donor as a model for investigating AD-associated gene regulatory networks.
Hossini AM; Megges M; Prigione A; Lichtner B; Toliat MR; Wruck W; Schröter F; Nuernberg P; Kroll H; Makrantonaki E; Zouboulis CC; Adjaye J
BMC Genomics; 2015 Feb; 16(1):84. PubMed ID: 25765079
[TBL] [Abstract][Full Text] [Related]
2. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
Ochalek A; Mihalik B; Avci HX; Chandrasekaran A; Téglási A; Bock I; Giudice ML; Táncos Z; Molnár K; László L; Nielsen JE; Holst B; Freude K; Hyttel P; Kobolák J; Dinnyés A
Alzheimers Res Ther; 2017 Dec; 9(1):90. PubMed ID: 29191219
[TBL] [Abstract][Full Text] [Related]
3. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.
Israel MA; Yuan SH; Bardy C; Reyna SM; Mu Y; Herrera C; Hefferan MP; Van Gorp S; Nazor KL; Boscolo FS; Carson CT; Laurent LC; Marsala M; Gage FH; Remes AM; Koo EH; Goldstein LS
Nature; 2012 Jan; 482(7384):216-20. PubMed ID: 22278060
[TBL] [Abstract][Full Text] [Related]
4. Modeling Alzheimer's Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation.
Chang KH; Lee-Chen GJ; Huang CC; Lin JL; Chen YJ; Wei PC; Lo YS; Yao CF; Kuo MW; Chen CM
Mol Neurobiol; 2019 Jun; 56(6):3972-3983. PubMed ID: 30238389
[TBL] [Abstract][Full Text] [Related]
5. Altered CpG methylation in sporadic Alzheimer's disease is associated with APP and MAPT dysregulation.
Iwata A; Nagata K; Hatsuta H; Takuma H; Bundo M; Iwamoto K; Tamaoka A; Murayama S; Saido T; Tsuji S
Hum Mol Genet; 2014 Feb; 23(3):648-56. PubMed ID: 24101602
[TBL] [Abstract][Full Text] [Related]
6. Gamma secretase modulators and BACE inhibitors reduce Aβ production without altering gene expression in Alzheimer's disease iPSC-derived neurons and mice.
Cusulin C; Wells I; Badillo S; Duran-Pacheco GC; Baumann K; Patsch C
Mol Cell Neurosci; 2019 Oct; 100():103392. PubMed ID: 31381983
[TBL] [Abstract][Full Text] [Related]
7. Alzheimer's disease-related amyloid-β induces synaptotoxicity in human iPS cell-derived neurons.
Nieweg K; Andreyeva A; van Stegen B; Tanriöver G; Gottmann K
Cell Death Dis; 2015 Apr; 6(4):e1709. PubMed ID: 25837485
[TBL] [Abstract][Full Text] [Related]
8. Quantitative expression analysis of APP pathway and tau phosphorylation-related genes in the ICV STZ-induced non-human primate model of sporadic Alzheimer's disease.
Park SJ; Kim YH; Nam GH; Choe SH; Lee SR; Kim SU; Kim JS; Sim BW; Song BS; Jeong KJ; Lee Y; Park YI; Lee KM; Huh JW; Chang KT
Int J Mol Sci; 2015 Jan; 16(2):2386-402. PubMed ID: 25622254
[TBL] [Abstract][Full Text] [Related]
9. Modeling familial Alzheimer's disease with induced pluripotent stem cells.
Yagi T; Ito D; Okada Y; Akamatsu W; Nihei Y; Yoshizaki T; Yamanaka S; Okano H; Suzuki N
Hum Mol Genet; 2011 Dec; 20(23):4530-9. PubMed ID: 21900357
[TBL] [Abstract][Full Text] [Related]
10. Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.
Martiskainen H; Viswanathan J; Nykänen NP; Kurki M; Helisalmi S; Natunen T; Sarajärvi T; Kurkinen KM; Pursiheimo JP; Rauramaa T; Alafuzoff I; Jääskeläinen JE; Leinonen V; Soininen H; Haapasalo A; Huttunen HJ; Hiltunen M
Neurobiol Aging; 2015 Feb; 36(2):1221.e15-28. PubMed ID: 25281018
[TBL] [Abstract][Full Text] [Related]
11. Pathological manifestation of the induced pluripotent stem cell-derived cortical neurons from an early-onset Alzheimer's disease patient carrying a presenilin-1 mutation (S170F).
Li L; Kim HJ; Roh JH; Kim M; Koh W; Kim Y; Heo H; Chung J; Nakanishi M; Yoon T; Hong CP; Seo SW; Na DL; Song J
Cell Prolif; 2020 Apr; 53(4):e12798. PubMed ID: 32216003
[TBL] [Abstract][Full Text] [Related]
12. Stem Cell-Derived Neurons as Cellular Models of Sporadic Alzheimer's Disease.
Foveau B; Correia AS; Hébert SS; Rainone S; Potvin O; Kergoat MJ; Belleville S; Duchesne S; LeBlanc AC;
J Alzheimers Dis; 2019; 67(3):893-910. PubMed ID: 30689579
[TBL] [Abstract][Full Text] [Related]
13. N-butylidenephthalide attenuates Alzheimer's disease-like cytopathy in Down syndrome induced pluripotent stem cell-derived neurons.
Chang CY; Chen SM; Lu HE; Lai SM; Lai PS; Shen PW; Chen PY; Shen CI; Harn HJ; Lin SZ; Hwang SM; Su HL
Sci Rep; 2015 Mar; 5():8744. PubMed ID: 25735452
[TBL] [Abstract][Full Text] [Related]
14. The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons.
Muratore CR; Rice HC; Srikanth P; Callahan DG; Shin T; Benjamin LN; Walsh DM; Selkoe DJ; Young-Pearse TL
Hum Mol Genet; 2014 Jul; 23(13):3523-36. PubMed ID: 24524897
[TBL] [Abstract][Full Text] [Related]
15. Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.
Koch P; Tamboli IY; Mertens J; Wunderlich P; Ladewig J; Stüber K; Esselmann H; Wiltfang J; Brüstle O; Walter J
Am J Pathol; 2012 Jun; 180(6):2404-16. PubMed ID: 22510327
[TBL] [Abstract][Full Text] [Related]
16. Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.
Muratore CR; Zhou C; Liao M; Fernandez MA; Taylor WM; Lagomarsino VN; Pearse RV; Rice HC; Negri JM; He A; Srikanth P; Callahan DG; Shin T; Zhou M; Bennett DA; Noggle S; Love JC; Selkoe DJ; Young-Pearse TL
Stem Cell Reports; 2017 Dec; 9(6):1868-1884. PubMed ID: 29153990
[TBL] [Abstract][Full Text] [Related]
17. Kidins220 accumulates with tau in human Alzheimer's disease and related models: modulation of its calpain-processing by GSK3β/PP1 imbalance.
López-Menéndez C; Gamir-Morralla A; Jurado-Arjona J; Higuero AM; Campanero MR; Ferrer I; Hernández F; Ávila J; Díaz-Guerra M; Iglesias T
Hum Mol Genet; 2013 Feb; 22(3):466-82. PubMed ID: 23118350
[TBL] [Abstract][Full Text] [Related]
18. Meta-Analysis of Transcriptome Data Related to Hippocampus Biopsies and iPSC-Derived Neuronal Cells from Alzheimer's Disease Patients Reveals an Association with FOXA1 and FOXA2 Gene Regulatory Networks.
Wruck W; Schröter F; Adjaye J
J Alzheimers Dis; 2016; 50(4):1065-82. PubMed ID: 26890743
[TBL] [Abstract][Full Text] [Related]
19. The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease.
Watanabe K; Uemura K; Asada M; Maesako M; Akiyama H; Shimohama S; Takahashi R; Kinoshita A
Mol Brain; 2015 Dec; 8(1):82. PubMed ID: 26637371
[TBL] [Abstract][Full Text] [Related]
20. Modeling Late-Onset Sporadic Alzheimer's Disease through BMI1 Deficiency.
Flamier A; El Hajjar J; Adjaye J; Fernandes KJ; Abdouh M; Bernier G
Cell Rep; 2018 May; 23(9):2653-2666. PubMed ID: 29847796
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
