243 related articles for article (PubMed ID: 25766236)
1. K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.
Dong YY; Pike AC; Mackenzie A; McClenaghan C; Aryal P; Dong L; Quigley A; Grieben M; Goubin S; Mukhopadhyay S; Ruda GF; Clausen MV; Cao L; Brennan PE; Burgess-Brown NA; Sansom MS; Tucker SJ; Carpenter EP
Science; 2015 Mar; 347(6227):1256-9. PubMed ID: 25766236
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine.
Kennard LE; Chumbley JR; Ranatunga KM; Armstrong SJ; Veale EL; Mathie A
Br J Pharmacol; 2005 Mar; 144(6):821-9. PubMed ID: 15685212
[TBL] [Abstract][Full Text] [Related]
3. Mechanism of Mechanosensitive Gating of the TREK-2 Potassium Channel.
Brennecke JT; de Groot BL
Biophys J; 2018 Mar; 114(6):1336-1343. PubMed ID: 29590591
[TBL] [Abstract][Full Text] [Related]
4. Polynuclear Ruthenium Amines Inhibit K
Pope L; Lolicato M; Minor DL
Cell Chem Biol; 2020 May; 27(5):511-524.e4. PubMed ID: 32059793
[TBL] [Abstract][Full Text] [Related]
5. Neutralization of a single arginine residue gates open a two-pore domain, alkali-activated K+ channel.
Niemeyer MI; González-Nilo FD; Zúñiga L; González W; Cid LP; Sepúlveda FV
Proc Natl Acad Sci U S A; 2007 Jan; 104(2):666-71. PubMed ID: 17197424
[TBL] [Abstract][Full Text] [Related]
6. Disruption of palmitate-mediated localization; a shared pathway of force and anesthetic activation of TREK-1 channels.
Petersen EN; Pavel MA; Wang H; Hansen SB
Biochim Biophys Acta Biomembr; 2020 Jan; 1862(1):183091. PubMed ID: 31672538
[TBL] [Abstract][Full Text] [Related]
7. The Inhibition of TREK-1 K
Miyano K; Nonaka M; Sakamoto M; Murofushi M; Yoshida Y; Komura K; Ohbuchi K; Higami Y; Fujii H; Uezono Y
Int J Mol Sci; 2024 Apr; 25(9):. PubMed ID: 38732124
[TBL] [Abstract][Full Text] [Related]
8. A TREK inhibitor takes multiple tracks.
Short B
J Gen Physiol; 2021 Aug; 153(8):. PubMed ID: 34232275
[TBL] [Abstract][Full Text] [Related]
9. Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels.
Türkaydin B; Schewe M; Riel EB; Schulz F; Biedermann J; Baukrowitz T; Sun H
Nat Commun; 2024 May; 15(1):4628. PubMed ID: 38821927
[TBL] [Abstract][Full Text] [Related]
10. Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.
Rödström KEJ; Cloake A; Sörmann J; Baronina A; Smith KHM; Pike ACW; Ang J; Proks P; Schewe M; Holland-Kaye I; Bushell SR; Elliott J; Pardon E; Baukrowitz T; Owens RJ; Newstead S; Steyaert J; Carpenter EP; Tucker SJ
Nat Commun; 2024 May; 15(1):4173. PubMed ID: 38755204
[TBL] [Abstract][Full Text] [Related]
11. C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Lin H; Li J; Zhang Q; Yang H; Chen S
Proc Natl Acad Sci U S A; 2024 Apr; 121(17):e2320345121. PubMed ID: 38630723
[TBL] [Abstract][Full Text] [Related]
12. Tension activation of mechanosensitive two-pore domain K+ channels TRAAK, TREK-1, and TREK-2.
Sorum B; Docter T; Panico V; Rietmeijer RA; Brohawn SG
Nat Commun; 2024 Apr; 15(1):3142. PubMed ID: 38605031
[TBL] [Abstract][Full Text] [Related]
13. Structural basis of ligand specificity and channel activation in an insect gustatory receptor.
Frank HM; Walujkar S; Walsh RM; Laursen WJ; Theobald DL; Garrity PA; Gaudet R
Cell Rep; 2024 Apr; 43(4):114035. PubMed ID: 38573859
[TBL] [Abstract][Full Text] [Related]
14. Unlocking Therapeutic Synergy: Tailoring Drugs for Comorbidities such as Depression and Diabetes through Identical Molecular Targets in Different Cell Types.
Coppola T; Daziano G; Legroux I; Béraud-Dufour S; Blondeau N; Lebrun P
Cells; 2023 Dec; 12(23):. PubMed ID: 38067196
[TBL] [Abstract][Full Text] [Related]
15. Development of covalent chemogenetic K
Deal PE; Lee H; Mondal A; Lolicato M; de Mendonca PRF; Black H; El-Hilali X; Bryant C; Isacoff EY; Renslo AR; Minor DL
bioRxiv; 2023 Oct; ():. PubMed ID: 37905049
[TBL] [Abstract][Full Text] [Related]
16. The Inhibitory Effect of Magnolol on the Human TWIK1 Channel Is Related to G229 and T225 Sites.
Wang J; Liu H; Sun Z; Zou X; Zhang Z; Wei X; Pan L; Stalin A; Zhao W; Chen Y
Molecules; 2023 Sep; 28(19):. PubMed ID: 37836658
[TBL] [Abstract][Full Text] [Related]
17. Calcium-gated potassium channel blockade via membrane-facing fenestrations.
Fan C; Flood E; Sukomon N; Agarwal S; Allen TW; Nimigean CM
Nat Chem Biol; 2024 Jan; 20(1):52-61. PubMed ID: 37653172
[TBL] [Abstract][Full Text] [Related]
18.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
19.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
20.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Next] [New Search]