These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

48 related articles for article (PubMed ID: 25768114)

  • 1. Correction: UFSRAT: Ultra-Fast Shape Recognition with Atom Types--the discovery of novel bioactive small molecular scaffolds for FKBP12 and 11βHSD1.
    PLOS ONE Staff
    PLoS One; 2015; 10(3):e0122658. PubMed ID: 25768114
    [No Abstract]   [Full Text] [Related]  

  • 2. UFSRAT: Ultra-fast Shape Recognition with Atom Types--the discovery of novel bioactive small molecular scaffolds for FKBP12 and 11βHSD1.
    Shave S; Blackburn EA; Adie J; Houston DR; Auer M; Webster SP; Taylor P; Walkinshaw MD
    PLoS One; 2015; 10(2):e0116570. PubMed ID: 25659145
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Database of bioactive ring systems with calculated properties and its use in bioisosteric design and scaffold hopping.
    Ertl P
    Bioorg Med Chem; 2012 Sep; 20(18):5436-42. PubMed ID: 22436390
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mean field analysis of FKBP12 complexes with FK506 and rapamycin: implications for a role of crystallographic water molecules in molecular recognition and specificity.
    Rejto PA; Verkhivker GM
    Proteins; 1997 Jul; 28(3):313-24. PubMed ID: 9223178
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quest for the rings. In silico exploration of ring universe to identify novel bioactive heteroaromatic scaffolds.
    Ertl P; Jelfs S; Mühlbacher J; Schuffenhauer A; Selzer P
    J Med Chem; 2006 Jul; 49(15):4568-73. PubMed ID: 16854061
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ADME evaluation in drug discovery. 2. Prediction of partition coefficient by atom-additive approach based on atom-weighted solvent accessible surface areas.
    Hou TJ; Xu XJ
    J Chem Inf Comput Sci; 2003; 43(3):1058-67. PubMed ID: 12767165
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mining for bioactive scaffolds with scaffold networks: improved compound set enrichment from primary screening data.
    Varin T; Schuffenhauer A; Ertl P; Renner S
    J Chem Inf Model; 2011 Jul; 51(7):1528-38. PubMed ID: 21615076
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A fast method using a new hydrophilic-lipophilic balanced sorbent in combination with ultra-high performance liquid chromatography for quantification of significant bioactive metabolites in wines.
    Silva CL; Pereira J; Wouter VG; Giró C; Câmara JS
    Talanta; 2011 Oct; 86():82-90. PubMed ID: 22063514
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular similarity including chirality.
    Armstrong MS; Morris GM; Finn PW; Sharma R; Richards WG
    J Mol Graph Model; 2009 Nov; 28(4):368-70. PubMed ID: 19801197
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FK506-binding protein 12 ligands: a patent review.
    Liu F; Wang YQ; Meng L; Gu M; Tan RY
    Expert Opin Ther Pat; 2013 Nov; 23(11):1435-49. PubMed ID: 23957229
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Many drugs contain unique scaffolds with varying structural relationships to scaffolds of currently available bioactive compounds.
    Hu Y; Bajorath J
    Eur J Med Chem; 2014 Apr; 76():427-34. PubMed ID: 24602788
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rapid measurement of multidimensional 1H solid-state NMR spectra at ultra-fast MAS frequencies.
    Ye YQ; Malon M; Martineau C; Taulelle F; Nishiyama Y
    J Magn Reson; 2014 Feb; 239():75-80. PubMed ID: 24424008
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Affinity purification of the ryanodine receptor/calcium release channel from fast twitch skeletal muscle based on its tight association with FKBP12.
    Xin HB; Timerman AP; Onoue H; Wiederrecht GJ; Fleischer S
    Biochem Biophys Res Commun; 1995 Sep; 214(1):263-70. PubMed ID: 7669046
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Chemical study on bioactive natural products of novel structural types].
    Yu SS; Feng XZ
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2004 Aug; 26(4):347-50. PubMed ID: 15379253
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mesoporous bioactive glass scaffolds for efficient delivery of vascular endothelial growth factor.
    Wu C; Fan W; Chang J; Xiao Y
    J Biomater Appl; 2013 Sep; 28(3):367-74. PubMed ID: 22781919
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction.
    Rush TS; Grant JA; Mosyak L; Nicholls A
    J Med Chem; 2005 Mar; 48(5):1489-95. PubMed ID: 15743191
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Scaffold hopping through virtual screening using 2D and 3D similarity descriptors: ranking, voting, and consensus scoring.
    Zhang Q; Muegge I
    J Med Chem; 2006 Mar; 49(5):1536-48. PubMed ID: 16509572
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of four novel natural product inspired scaffolds for drug discovery.
    Jenkins ID; Lacrampe F; Ripper J; Alcaraz L; Le PV; Nikolakopoulos G; de Almeida Leone P; White RH; Quinn RJ
    J Org Chem; 2009 Feb; 74(3):1304-13. PubMed ID: 19105637
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Skeletal muscle 11βHSD1 activity of nondiabetic subjects is unaltered in central obesity-associated insulin resistance.
    Inder WJ; Obeyesekere VR; Alford FP; Jang C
    Horm Metab Res; 2011 Apr; 43(4):257-60. PubMed ID: 21249616
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of contribution of 11betaHSD1 and glucocorticoid action to reduced muscle mass associated with reduced growth hormone action.
    Itoh E; Iida K; Kim DS; Del Rincon JP; Coschigano KT; Kopchick JJ; Thorner MO
    Growth Horm IGF Res; 2004 Dec; 14(6):462-6. PubMed ID: 15519255
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 3.