363 related articles for article (PubMed ID: 25768905)
1. Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels.
Gennarino VA; Singh RK; White JJ; De Maio A; Han K; Kim JY; Jafar-Nejad P; di Ronza A; Kang H; Sayegh LS; Cooper TA; Orr HT; Sillitoe RV; Zoghbi HY
Cell; 2015 Mar; 160(6):1087-98. PubMed ID: 25768905
[TBL] [Abstract][Full Text] [Related]
2. Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.
Crespo-Barreto J; Fryer JD; Shaw CA; Orr HT; Zoghbi HY
PLoS Genet; 2010 Jul; 6(7):e1001021. PubMed ID: 20628574
[TBL] [Abstract][Full Text] [Related]
3. Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3epsilon haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration.
Jafar-Nejad P; Ward CS; Richman R; Orr HT; Zoghbi HY
Proc Natl Acad Sci U S A; 2011 Feb; 108(5):2142-7. PubMed ID: 21245341
[TBL] [Abstract][Full Text] [Related]
4. Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.
Watase K; Gatchel JR; Sun Y; Emamian E; Atkinson R; Richman R; Mizusawa H; Orr HT; Shaw C; Zoghbi HY
PLoS Med; 2007 May; 4(5):e182. PubMed ID: 17535104
[TBL] [Abstract][Full Text] [Related]
5. The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1.
Venkatraman A; Hu YS; Didonna A; Cvetanovic M; Krbanjevic A; Bilesimo P; Opal P
Hum Mol Genet; 2014 Jul; 23(14):3733-45. PubMed ID: 24594842
[TBL] [Abstract][Full Text] [Related]
6. A Mild PUM1 Mutation Is Associated with Adult-Onset Ataxia, whereas Haploinsufficiency Causes Developmental Delay and Seizures.
Gennarino VA; Palmer EE; McDonell LM; Wang L; Adamski CJ; Koire A; See L; Chen CA; Schaaf CP; Rosenfeld JA; Panzer JA; Moog U; Hao S; Bye A; Kirk EP; Stankiewicz P; Breman AM; McBride A; Kandula T; Dubbs HA; Macintosh R; Cardamone M; Zhu Y; Ying K; Dias KR; Cho MT; Henderson LB; Baskin B; Morris P; Tao J; Cowley MJ; Dinger ME; Roscioli T; Caluseriu O; Suchowersky O; Sachdev RK; Lichtarge O; Tang J; Boycott KM; Holder JL; Zoghbi HY
Cell; 2018 Feb; 172(5):924-936.e11. PubMed ID: 29474920
[TBL] [Abstract][Full Text] [Related]
7. Progress in pathogenesis studies of spinocerebellar ataxia type 1.
Cummings CJ; Orr HT; Zoghbi HY
Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1079-81. PubMed ID: 10434309
[TBL] [Abstract][Full Text] [Related]
8. Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model.
Gehrking KM; Andresen JM; Duvick L; Lough J; Zoghbi HY; Orr HT
Hum Mol Genet; 2011 Jun; 20(11):2204-12. PubMed ID: 21427130
[TBL] [Abstract][Full Text] [Related]
9. Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1.
Emir UE; Brent Clark H; Vollmers ML; Eberly LE; Öz G
J Neurochem; 2013 Dec; 127(5):660-8. PubMed ID: 24032423
[TBL] [Abstract][Full Text] [Related]
10. A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1.
Sánchez I; Piñol P; Corral-Juan M; Pandolfo M; Matilla-Dueñas A
Hum Mol Genet; 2013 Sep; 22(17):3425-37. PubMed ID: 23630944
[TBL] [Abstract][Full Text] [Related]
11. A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration.
Watase K; Weeber EJ; Xu B; Antalffy B; Yuva-Paylor L; Hashimoto K; Kano M; Atkinson R; Sun Y; Armstrong DL; Sweatt JD; Orr HT; Paylor R; Zoghbi HY
Neuron; 2002 Jun; 34(6):905-19. PubMed ID: 12086639
[TBL] [Abstract][Full Text] [Related]
12. PUMILIO1 Links Epilepsy to Spinocerebellar Ataxia.
Lyman KA; Chetkovich DM
Epilepsy Curr; 2019; 19(2):122-123. PubMed ID: 30955425
[TBL] [Abstract][Full Text] [Related]
13. Polyglutamine disease toxicity is regulated by Nemo-like kinase in spinocerebellar ataxia type 1.
Ju H; Kokubu H; Todd TW; Kahle JJ; Kim S; Richman R; Chirala K; Orr HT; Zoghbi HY; Lim J
J Neurosci; 2013 May; 33(22):9328-36. PubMed ID: 23719801
[TBL] [Abstract][Full Text] [Related]
14. Glial S100B protein modulates mutant ataxin-1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy.
Vig PJ; Hearst S; Shao Q; Lopez ME; Murphy HA; Safaya E
Cerebellum; 2011 Jun; 10(2):254-66. PubMed ID: 21384195
[TBL] [Abstract][Full Text] [Related]
15. Exercise and genetic rescue of SCA1 via the transcriptional repressor Capicua.
Fryer JD; Yu P; Kang H; Mandel-Brehm C; Carter AN; Crespo-Barreto J; Gao Y; Flora A; Shaw C; Orr HT; Zoghbi HY
Science; 2011 Nov; 334(6056):690-3. PubMed ID: 22053053
[TBL] [Abstract][Full Text] [Related]
16. Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1.
Edamakanti CR; Do J; Didonna A; Martina M; Opal P
J Clin Invest; 2018 Jun; 128(6):2252-2265. PubMed ID: 29533923
[TBL] [Abstract][Full Text] [Related]
17. Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice.
Zu T; Duvick LA; Kaytor MD; Berlinger MS; Zoghbi HY; Clark HB; Orr HT
J Neurosci; 2004 Oct; 24(40):8853-61. PubMed ID: 15470152
[TBL] [Abstract][Full Text] [Related]
18. Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures.
Skinner PJ; Koshy BT; Cummings CJ; Klement IA; Helin K; Servadio A; Zoghbi HY; Orr HT
Nature; 1997 Oct; 389(6654):971-4. PubMed ID: 9353120
[TBL] [Abstract][Full Text] [Related]
19. Noninvasive detection of presymptomatic and progressive neurodegeneration in a mouse model of spinocerebellar ataxia type 1.
Oz G; Nelson CD; Koski DM; Henry PG; Marjanska M; Deelchand DK; Shanley R; Eberly LE; Orr HT; Clark HB
J Neurosci; 2010 Mar; 30(10):3831-8. PubMed ID: 20220018
[TBL] [Abstract][Full Text] [Related]
20. Down-regulation of the dopamine receptor D2 in mice lacking ataxin 1.
Goold R; Hubank M; Hunt A; Holton J; Menon RP; Revesz T; Pandolfo M; Matilla-Dueñas A
Hum Mol Genet; 2007 Sep; 16(17):2122-34. PubMed ID: 17599952
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
