These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 25768905)

  • 41. Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes.
    Bowman AB; Lam YC; Jafar-Nejad P; Chen HK; Richman R; Samaco RC; Fryer JD; Kahle JJ; Orr HT; Zoghbi HY
    Nat Genet; 2007 Mar; 39(3):373-9. PubMed ID: 17322884
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Vascular endothelial growth factor ameliorates the ataxic phenotype in a mouse model of spinocerebellar ataxia type 1.
    Cvetanovic M; Patel JM; Marti HH; Kini AR; Opal P
    Nat Med; 2011 Oct; 17(11):1445-7. PubMed ID: 22001907
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Identification of genes that modify ataxin-1-induced neurodegeneration.
    Fernandez-Funez P; Nino-Rosales ML; de Gouyon B; She WC; Luchak JM; Martinez P; Turiegano E; Benito J; Capovilla M; Skinner PJ; McCall A; Canal I; Orr HT; Zoghbi HY; Botas J
    Nature; 2000 Nov; 408(6808):101-6. PubMed ID: 11081516
    [TBL] [Abstract][Full Text] [Related]  

  • 44. p80 coilin, a coiled body-specific protein, interacts with ataxin-1, the SCA1 gene product.
    Hong S; Ka S; Kim S; Park Y; Kang S
    Biochim Biophys Acta; 2003 May; 1638(1):35-42. PubMed ID: 12757932
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua.
    Kim E; Lu HC; Zoghbi HY; Song JJ
    Genes Dev; 2013 Mar; 27(6):590-5. PubMed ID: 23512657
    [TBL] [Abstract][Full Text] [Related]  

  • 46. SCA1 transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat.
    Burright EN; Clark HB; Servadio A; Matilla T; Feddersen RM; Yunis WS; Duvick LA; Zoghbi HY; Orr HT
    Cell; 1995 Sep; 82(6):937-48. PubMed ID: 7553854
    [TBL] [Abstract][Full Text] [Related]  

  • 47. USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.
    Hong S; Kim SJ; Ka S; Choi I; Kang S
    Mol Cell Neurosci; 2002 Jun; 20(2):298-306. PubMed ID: 12093161
    [TBL] [Abstract][Full Text] [Related]  

  • 48. The ubiquitin-conjugating enzyme UbcH6 regulates the transcriptional repression activity of the SCA1 gene product ataxin-1.
    Lee S; Hong S; Kang S
    Biochem Biophys Res Commun; 2008 Aug; 372(4):735-40. PubMed ID: 18519031
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, spinocerebellar ataxia type 1.
    Zoghbi HY; Orr HT
    J Biol Chem; 2009 Mar; 284(12):7425-9. PubMed ID: 18957430
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Repeat instability and motor incoordination in mice with a targeted expanded CAG repeat in the Sca1 locus.
    Lorenzetti D; Watase K; Xu B; Matzuk MM; Orr HT; Zoghbi HY
    Hum Mol Genet; 2000 Mar; 9(5):779-85. PubMed ID: 10749985
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Altered Purkinje cell miRNA expression and SCA1 pathogenesis.
    Rodriguez-Lebron E; Liu G; Keiser M; Behlke MA; Davidson BL
    Neurobiol Dis; 2013 Jun; 54():456-63. PubMed ID: 23376683
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Mice lacking ataxin-1 display learning deficits and decreased hippocampal paired-pulse facilitation.
    Matilla A; Roberson ED; Banfi S; Morales J; Armstrong DL; Burright EN; Orr HT; Sweatt JD; Zoghbi HY; Matzuk MM
    J Neurosci; 1998 Jul; 18(14):5508-16. PubMed ID: 9651231
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Motor neuron degeneration correlates with respiratory dysfunction in SCA1.
    Orengo JP; van der Heijden ME; Hao S; Tang J; Orr HT; Zoghbi HY
    Dis Model Mech; 2018 Feb; 11(2):. PubMed ID: 29419414
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Imperfect CAG repeats form diverse structures in SCA1 transcripts.
    Sobczak K; Krzyzosiak WJ
    J Biol Chem; 2004 Oct; 279(40):41563-72. PubMed ID: 15292212
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Phosphorylation of ATXN1 at Ser776 in the cerebellum.
    Jorgensen ND; Andresen JM; Lagalwar S; Armstrong B; Stevens S; Byam CE; Duvick LA; Lai S; Jafar-Nejad P; Zoghbi HY; Clark HB; Orr HT
    J Neurochem; 2009 Jul; 110(2):675-86. PubMed ID: 19500214
    [TBL] [Abstract][Full Text] [Related]  

  • 56. An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein.
    Bergeron D; Lapointe C; Bissonnette C; Tremblay G; Motard J; Roucou X
    J Biol Chem; 2013 Jul; 288(30):21824-35. PubMed ID: 23760502
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.
    Klement IA; Skinner PJ; Kaytor MD; Yi H; Hersch SM; Clark HB; Zoghbi HY; Orr HT
    Cell; 1998 Oct; 95(1):41-53. PubMed ID: 9778246
    [TBL] [Abstract][Full Text] [Related]  

  • 58. The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract.
    Yue S; Serra HG; Zoghbi HY; Orr HT
    Hum Mol Genet; 2001 Jan; 10(1):25-30. PubMed ID: 11136710
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Assessing the efficacy of specific cerebellomodulatory drugs for use as therapy for spinocerebellar ataxia type 1.
    Nag N; Tarlac V; Storey E
    Cerebellum; 2013 Feb; 12(1):74-82. PubMed ID: 22718440
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Impairment of spinal motor neurons in spinocerebellar ataxia type 1-knock-in mice.
    Takechi Y; Mieda T; Iizuka A; Toya S; Suto N; Takagishi K; Nakazato Y; Nakamura K; Hirai H
    Neurosci Lett; 2013 Feb; 535():67-72. PubMed ID: 23328439
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.