258 related articles for article (PubMed ID: 25769964)
1. Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
Morad SA; Tan SF; Feith DJ; Kester M; Claxton DF; Loughran TP; Barth BM; Fox TE; Cabot MC
Biochim Biophys Acta; 2015 Jul; 1851(7):919-28. PubMed ID: 25769964
[TBL] [Abstract][Full Text] [Related]
2. Tamoxifen regulation of sphingolipid metabolism--Therapeutic implications.
Morad SA; Cabot MC
Biochim Biophys Acta; 2015 Sep; 1851(9):1134-45. PubMed ID: 25964209
[TBL] [Abstract][Full Text] [Related]
3. Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells.
Morad SA; Levin JC; Tan SF; Fox TE; Feith DJ; Cabot MC
Biochim Biophys Acta; 2013 Dec; 1831(12):1657-64. PubMed ID: 23939396
[TBL] [Abstract][Full Text] [Related]
4. Dynamics of ceramide generation and metabolism in response to fenretinide--Diversity within and among leukemia.
Morad SA; Davis TS; Kester M; Loughran TP; Cabot MC
Leuk Res; 2015 Oct; 39(10):1071-8. PubMed ID: 26220867
[TBL] [Abstract][Full Text] [Related]
5. Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer.
Morad SAF; Davis TS; MacDougall MR; Tan SF; Feith DJ; Desai DH; Amin SG; Kester M; Loughran TP; Cabot MC
Biochem Pharmacol; 2017 Apr; 130():21-33. PubMed ID: 28189725
[TBL] [Abstract][Full Text] [Related]
6. SphK1 inhibitor II (SKI-II) inhibits acute myelogenous leukemia cell growth in vitro and in vivo.
Yang L; Weng W; Sun ZX; Fu XJ; Ma J; Zhuang WF
Biochem Biophys Res Commun; 2015 May; 460(4):903-8. PubMed ID: 25824043
[TBL] [Abstract][Full Text] [Related]
7. Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia.
Morad SA; Ryan TE; Neufer PD; Zeczycki TN; Davis TS; MacDougall MR; Fox TE; Tan SF; Feith DJ; Loughran TP; Kester M; Claxton DF; Barth BM; Deering TG; Cabot MC
J Lipid Res; 2016 Jul; 57(7):1231-42. PubMed ID: 27140664
[TBL] [Abstract][Full Text] [Related]
8. Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells.
Apraiz A; Idkowiak-Baldys JK; Boyano MD; Pérez-Yarza G; Hannun YA; Asumendi A
BMC Cancer; 2011 Nov; 11():477. PubMed ID: 22061047
[TBL] [Abstract][Full Text] [Related]
9. Pivotal role of mitophagy in response of acute myelogenous leukemia to a ceramide-tamoxifen-containing drug regimen.
Morad SAF; MacDougall MR; Abdelmageed N; Kao LP; Feith DJ; Tan SF; Kester M; Loughran TP; Wang HG; Cabot MC
Exp Cell Res; 2019 Aug; 381(2):256-264. PubMed ID: 31112736
[TBL] [Abstract][Full Text] [Related]
10. Ceramide Analogue SACLAC Modulates Sphingolipid Levels and
Pearson JM; Tan SF; Sharma A; Annageldiyev C; Fox TE; Abad JL; Fabrias G; Desai D; Amin S; Wang HG; Cabot MC; Claxton DF; Kester M; Feith DJ; Loughran TP
Mol Cancer Res; 2020 Mar; 18(3):352-363. PubMed ID: 31744877
[TBL] [Abstract][Full Text] [Related]
11. Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.
Kao LP; Morad SAF; Davis TS; MacDougall MR; Kassai M; Abdelmageed N; Fox TE; Kester M; Loughran TP; Abad JL; Fabrias G; Tan SF; Feith DJ; Claxton DF; Spiegel S; Fisher-Wellman KH; Cabot MC
J Lipid Res; 2019 Sep; 60(9):1590-1602. PubMed ID: 31363040
[TBL] [Abstract][Full Text] [Related]
12. Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism.
Maurer BJ; Melton L; Billups C; Cabot MC; Reynolds CP
J Natl Cancer Inst; 2000 Dec; 92(23):1897-909. PubMed ID: 11106681
[TBL] [Abstract][Full Text] [Related]
13. Altering Sphingolipid Metabolism Attenuates Cell Death and Inflammatory Response After Myocardial Infarction.
Hadas Y; Vincek AS; Youssef E; Żak MM; Chepurko E; Sultana N; Sharkar MTK; Guo N; Komargodski R; Kurian AA; Kaur K; Magadum A; Fargnoli A; Katz MG; Hossain N; Kenigsberg E; Dubois NC; Schadt E; Hajjar R; Eliyahu E; Zangi L
Circulation; 2020 Mar; 141(11):916-930. PubMed ID: 31992066
[TBL] [Abstract][Full Text] [Related]
14. Acid ceramidase is upregulated in AML and represents a novel therapeutic target.
Tan SF; Liu X; Fox TE; Barth BM; Sharma A; Turner SD; Awwad A; Dewey A; Doi K; Spitzer B; Shah MV; Morad SA; Desai D; Amin S; Zhu J; Liao J; Yun J; Kester M; Claxton DF; Wang HG; Cabot MC; Schuchman EH; Levine RL; Feith DJ; Loughran TP
Oncotarget; 2016 Dec; 7(50):83208-83222. PubMed ID: 27825124
[TBL] [Abstract][Full Text] [Related]
15. Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function.
Ghazaly EA; Miraki-Moud F; Smith P; Gnanaranjan C; Koniali L; Oke A; Saied MH; Petty R; Matthews J; Stronge R; Joel SP; Young BD; Gribben J; Taussig DC
J Biol Chem; 2020 Apr; 295(16):5496-5508. PubMed ID: 32161116
[TBL] [Abstract][Full Text] [Related]
16. Concurrent targeting Akt and sphingosine kinase 1 by A-674563 in acute myeloid leukemia cells.
Xu L; Zhang Y; Gao M; Wang G; Fu Y
Biochem Biophys Res Commun; 2016 Apr; 472(4):662-8. PubMed ID: 26920060
[TBL] [Abstract][Full Text] [Related]
17. Disruption of sphingolipid metabolism augments ceramide-induced autophagy in preeclampsia.
Melland-Smith M; Ermini L; Chauvin S; Craig-Barnes H; Tagliaferro A; Todros T; Post M; Caniggia I
Autophagy; 2015 Apr; 11(4):653-69. PubMed ID: 25853898
[TBL] [Abstract][Full Text] [Related]
18. Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1.
Bonhoure E; Pchejetski D; Aouali N; Morjani H; Levade T; Kohama T; Cuvillier O
Leukemia; 2006 Jan; 20(1):95-102. PubMed ID: 16281067
[TBL] [Abstract][Full Text] [Related]
19. A novel mechanism of dasatinib-induced apoptosis in chronic myeloid leukemia; ceramide synthase and ceramide clearance genes.
Gencer EB; Ural AU; Avcu F; Baran Y
Ann Hematol; 2011 Nov; 90(11):1265-75. PubMed ID: 21455605
[TBL] [Abstract][Full Text] [Related]
20. The roles of bioactive sphingolipids in resveratrol-induced apoptosis in HL60: acute myeloid leukemia cells.
Cakir Z; Saydam G; Sahin F; Baran Y
J Cancer Res Clin Oncol; 2011 Feb; 137(2):279-86. PubMed ID: 20401667
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]