542 related articles for article (PubMed ID: 25773675)
1. CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase.
Singh AK; Pati U
Aging Cell; 2015 Aug; 14(4):595-604. PubMed ID: 25773675
[TBL] [Abstract][Full Text] [Related]
2. Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.
Zhang M; Deng Y; Luo Y; Zhang S; Zou H; Cai F; Wada K; Song W
J Neurochem; 2012 Mar; 120(6):1129-38. PubMed ID: 22212137
[TBL] [Abstract][Full Text] [Related]
3. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
4. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
5. SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer's disease amyloidosis and improves synaptic function.
Gong B; Chen F; Pan Y; Arrieta-Cruz I; Yoshida Y; Haroutunian V; Pasinetti GM
Aging Cell; 2010 Dec; 9(6):1018-31. PubMed ID: 20854419
[TBL] [Abstract][Full Text] [Related]
6. Lys(203) and Lys(382) are essential for the proteasomal degradation of BACE1.
Wang R; Ying Z; Zhao J; Zhang Y; Wang R; Lu H; Deng Y; Song W; Qing H
Curr Alzheimer Res; 2012 Jun; 9(5):606-15. PubMed ID: 22299711
[TBL] [Abstract][Full Text] [Related]
7. Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
Chen CH; Zhou W; Liu S; Deng Y; Cai F; Tone M; Tone Y; Tong Y; Song W
Int J Neuropsychopharmacol; 2012 Feb; 15(1):77-90. PubMed ID: 21329555
[TBL] [Abstract][Full Text] [Related]
8. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC
Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376
[TBL] [Abstract][Full Text] [Related]
9. Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes.
Sun X; Wang Y; Qing H; Christensen MA; Liu Y; Zhou W; Tong Y; Xiao C; Huang Y; Zhang S; Liu X; Song W
FASEB J; 2005 May; 19(7):739-49. PubMed ID: 15857888
[TBL] [Abstract][Full Text] [Related]
10. Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription.
Li Y; Zhou W; Tong Y; He G; Song W
FASEB J; 2006 Feb; 20(2):285-92. PubMed ID: 16449801
[TBL] [Abstract][Full Text] [Related]
11. Turnover of C99 is controlled by a crosstalk between ERAD and ubiquitin-independent lysosomal degradation in human neuroglioma cells.
Bustamante HA; Rivera-Dictter A; Cavieres VA; Muñoz VC; González A; Lin Y; Mardones GA; Burgos PV
PLoS One; 2013; 8(12):e83096. PubMed ID: 24376644
[TBL] [Abstract][Full Text] [Related]
12. A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels.
Espeseth AS; Huang Q; Gates A; Xu M; Yu Y; Simon AJ; Shi XP; Zhang X; Hodor P; Stone DJ; Burchard J; Cavet G; Bartz S; Linsley P; Ray WJ; Hazuda D
Mol Cell Neurosci; 2006 Nov; 33(3):227-35. PubMed ID: 16978875
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of FE65 Ser610 by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing.
Chow WN; Ngo JC; Li W; Chen YW; Tam KM; Chan HY; Miller CC; Lau KF
Biochem J; 2015 Sep; 470(3):303-17. PubMed ID: 26188042
[TBL] [Abstract][Full Text] [Related]
14. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
[TBL] [Abstract][Full Text] [Related]
15. Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.
Colombo A; Wang H; Kuhn PH; Page R; Kremmer E; Dempsey PJ; Crawford HC; Lichtenthaler SF
Neurobiol Dis; 2013 Jan; 49():137-47. PubMed ID: 22940630
[TBL] [Abstract][Full Text] [Related]
16. High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.
Maesako M; Uemura M; Tashiro Y; Sasaki K; Watanabe K; Noda Y; Ueda K; Asada-Utsugi M; Kubota M; Okawa K; Ihara M; Shimohama S; Uemura K; Kinoshita A
PLoS One; 2015; 10(9):e0131199. PubMed ID: 26414661
[TBL] [Abstract][Full Text] [Related]
17. Degradation of BACE by the ubiquitin-proteasome pathway.
Qing H; Zhou W; Christensen MA; Sun X; Tong Y; Song W
FASEB J; 2004 Oct; 18(13):1571-3. PubMed ID: 15289451
[TBL] [Abstract][Full Text] [Related]
18. The role of low-density receptor-related protein 1 (LRP1) as a competitive substrate of the amyloid precursor protein (APP) for BACE1.
von Einem B; Schwanzar D; Rehn F; Beyer AS; Weber P; Wagner M; Schneckenburger H; von Arnim CA
Exp Neurol; 2010 Sep; 225(1):85-93. PubMed ID: 20685197
[TBL] [Abstract][Full Text] [Related]
19. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
[TBL] [Abstract][Full Text] [Related]
20. Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.
Rossner S; Sastre M; Bourne K; Lichtenthaler SF
Prog Neurobiol; 2006 Jun; 79(2):95-111. PubMed ID: 16904810
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
