BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

450 related articles for article (PubMed ID: 25779936)

  • 1. A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells.
    Luo Y; Xu W; Chen H; Warburton D; Dong R; Qian B; Selman M; Gauldie J; Kolb M; Shi W
    J Pathol; 2015 Jul; 236(3):384-94. PubMed ID: 25779936
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway.
    Saito S; Zhuang Y; Shan B; Danchuk S; Luo F; Korfei M; Guenther A; Lasky JA
    PLoS One; 2017; 12(10):e0186615. PubMed ID: 29045477
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The anti-fibrotic effect of inhibition of TGFβ-ALK5 signalling in experimental pulmonary fibrosis in mice is attenuated in the presence of concurrent γ-herpesvirus infection.
    Smoktunowicz N; Alexander RE; Franklin L; Williams AE; Holman B; Mercer PF; Jarai G; Scotton CJ; Chambers RC
    Dis Model Mech; 2015 Sep; 8(9):1129-39. PubMed ID: 26138704
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling.
    Oruqaj G; Karnati S; Vijayan V; Kotarkonda LK; Boateng E; Zhang W; Ruppert C; Günther A; Shi W; Baumgart-Vogt E
    Proc Natl Acad Sci U S A; 2015 Apr; 112(16):E2048-57. PubMed ID: 25848047
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mimosa pudica L. extract ameliorates pulmonary fibrosis via modulation of MAPK signaling pathways and FOXO3 stabilization.
    Nguyen QC; Nguyen HA; Pham TA; Tran VT; Nguyen TD; Pham DV
    J Ethnopharmacol; 2024 Aug; 330():118226. PubMed ID: 38670401
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.
    Avouac J; Palumbo-Zerr K; Ruzehaji N; Tomcik M; Zerr P; Dees C; Distler A; Beyer C; Schneider H; Distler O; Schett G; Allanore Y; Distler JH
    Arthritis Rheumatol; 2014 Nov; 66(11):3140-50. PubMed ID: 25155144
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis.
    Daniels CE; Wilkes MC; Edens M; Kottom TJ; Murphy SJ; Limper AH; Leof EB
    J Clin Invest; 2004 Nov; 114(9):1308-16. PubMed ID: 15520863
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis.
    Hamanaka RB; Nigdelioglu R; Meliton AY; Tian Y; Witt LJ; O'Leary E; Sun KA; Woods PS; Wu D; Ansbro B; Ard S; Rohde JM; Dulin NO; Guzy RD; Mutlu GM
    Am J Respir Cell Mol Biol; 2018 May; 58(5):585-593. PubMed ID: 29019702
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model.
    Hoyles RK; Khan K; Shiwen X; Howat SL; Lindahl GE; Leoni P; du Bois RM; Wells AU; Black CM; Abraham DJ; Denton CP
    Arthritis Rheum; 2008 Apr; 58(4):1175-88. PubMed ID: 18383385
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhanced endogenous bone morphogenetic protein signaling protects against bleomycin induced pulmonary fibrosis.
    De Langhe E; Cailotto F; De Vooght V; Aznar-Lopez C; Vanoirbeek JA; Luyten FP; Lories RJ
    Respir Res; 2015 Mar; 16(1):38. PubMed ID: 25849157
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of cells expressing fibroblast activation protein has variable effects in models of TGF-β and chronic bleomycin-induced fibrosis.
    Kimura T; Monslow J; Klampatsa A; Leibowitz M; Sun J; Liousia M; Woodruff P; Moon E; Todd L; Puré E; Albelda SM
    Am J Physiol Lung Cell Mol Physiol; 2019 Aug; 317(2):L271-L282. PubMed ID: 31188013
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alpha2-antiplasmin regulates the development of dermal fibrosis in mice by prostaglandin F(2α) synthesis through adipose triglyceride lipase/calcium-independent phospholipase A(2).
    Kanno Y; Kawashita E; Kokado A; Okada K; Ueshima S; Matsuo O; Matsuno H
    Arthritis Rheum; 2013 Feb; 65(2):492-502. PubMed ID: 23124680
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment.
    Degryse AL; Tanjore H; Xu XC; Polosukhin VV; Jones BR; Boomershine CS; Ortiz C; Sherrill TP; McMahon FB; Gleaves LA; Blackwell TS; Lawson WE
    Am J Physiol Lung Cell Mol Physiol; 2011 Jun; 300(6):L887-97. PubMed ID: 21441353
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.
    Murray LA; Chen Q; Kramer MS; Hesson DP; Argentieri RL; Peng X; Gulati M; Homer RJ; Russell T; van Rooijen N; Elias JA; Hogaboam CM; Herzog EL
    Int J Biochem Cell Biol; 2011 Jan; 43(1):154-62. PubMed ID: 21044893
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aortic carboxypeptidase-like protein (ACLP) enhances lung myofibroblast differentiation through transforming growth factor β receptor-dependent and -independent pathways.
    Tumelty KE; Smith BD; Nugent MA; Layne MD
    J Biol Chem; 2014 Jan; 289(5):2526-36. PubMed ID: 24344132
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TNF-α-induced NF-κB activation promotes myofibroblast differentiation of LR-MSCs and exacerbates bleomycin-induced pulmonary fibrosis.
    Hou J; Ma T; Cao H; Chen Y; Wang C; Chen X; Xiang Z; Han X
    J Cell Physiol; 2018 Mar; 233(3):2409-2419. PubMed ID: 28731277
    [TBL] [Abstract][Full Text] [Related]  

  • 17. miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1.
    Lino Cardenas CL; Henaoui IS; Courcot E; Roderburg C; Cauffiez C; Aubert S; Copin MC; Wallaert B; Glowacki F; Dewaeles E; Milosevic J; Maurizio J; Tedrow J; Marcet B; Lo-Guidice JM; Kaminski N; Barbry P; Luedde T; Perrais M; Mari B; Pottier N
    PLoS Genet; 2013; 9(2):e1003291. PubMed ID: 23459460
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amplified canonical transforming growth factor-β signalling
    Sibinska Z; Tian X; Korfei M; Kojonazarov B; Kolb JS; Klepetko W; Kosanovic D; Wygrecka M; Ghofrani HA; Weissmann N; Grimminger F; Seeger W; Guenther A; Schermuly RT
    Eur Respir J; 2017 Feb; 49(2):. PubMed ID: 28182573
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
    Avouac J; Palumbo K; Tomcik M; Zerr P; Dees C; Horn A; Maurer B; Akhmetshina A; Beyer C; Sadowski A; Schneider H; Shiozawa S; Distler O; Schett G; Allanore Y; Distler JH
    Arthritis Rheum; 2012 May; 64(5):1642-52. PubMed ID: 22139817
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis.
    Hasegawa M; Matsushita Y; Horikawa M; Higashi K; Tomigahara Y; Kaneko H; Shirasaki F; Fujimoto M; Takehara K; Sato S
    Arthritis Rheum; 2009 Nov; 60(11):3465-75. PubMed ID: 19877032
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.