BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 25784680)

  • 1. Therapeutic targeting of HES1 transcriptional programs in T-ALL.
    Schnell SA; Ambesi-Impiombato A; Sanchez-Martin M; Belver L; Xu L; Qin Y; Kageyama R; Ferrando AA
    Blood; 2015 Apr; 125(18):2806-14. PubMed ID: 25784680
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group.
    Larson Gedman A; Chen Q; Kugel Desmoulin S; Ge Y; LaFiura K; Haska CL; Cherian C; Devidas M; Linda SB; Taub JW; Matherly LH
    Leukemia; 2009 Aug; 23(8):1417-25. PubMed ID: 19340001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prognostic implications of mutations in NOTCH1 and FBXW7 in childhood T-ALL treated according to the NOPHO ALL-1992 and ALL-2000 protocols.
    Fogelstrand L; Staffas A; Wasslavik C; Sjögren H; Söderhäll S; Frost BM; Forestier E; Degerman S; Behrendtz M; Heldrup J; Karrman K; Johansson B; Heyman M; Abrahamsson J; Palmqvist L
    Pediatr Blood Cancer; 2014 Mar; 61(3):424-30. PubMed ID: 24424791
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL.
    Sontani Y; Chapman G; Papathanasiou P; Dunwoodie S; Goodnow CC; Hoyne GF
    Leuk Res; 2011 Nov; 35(11):1512-9. PubMed ID: 21840596
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis.
    Uchida T; Kitaura J; Nakahara F; Togami K; Inoue D; Maehara A; Nishimura K; Kawabata KC; Doki N; Kakihana K; Yoshioka K; Izawa K; Oki T; Sada A; Harada Y; Ohashi K; Katayama Y; Matsui T; Harada H; Kitamura T
    Exp Hematol; 2014 May; 42(5):369-379.e3. PubMed ID: 24486648
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucocorticoid sensitivity of T-cell lymphoblastic leukemia/lymphoma is associated with glucocorticoid receptor-mediated inhibition of Notch1 expression.
    Cialfi S; Palermo R; Manca S; Checquolo S; Bellavia D; Pelullo M; Quaranta R; Dominici C; Gulino A; Screpanti I; Talora C
    Leukemia; 2013 Feb; 27(2):485-8. PubMed ID: 22846929
    [No Abstract]   [Full Text] [Related]  

  • 7. MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.
    Pajcini KV; Xu L; Shao L; Petrovic J; Palasiewicz K; Ohtani Y; Bailis W; Lee C; Wertheim GB; Mani R; Muthusamy N; Li Y; Meijerink JPP; Blacklow SC; Faryabi RB; Cherry S; Pear WS
    Sci Signal; 2017 Nov; 10(505):. PubMed ID: 29138297
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Notch/HES1-mediated PARP1 activation: a cell type-specific mechanism for tumor suppression.
    Kannan S; Fang W; Song G; Mullighan CG; Hammitt R; McMurray J; Zweidler-McKay PA
    Blood; 2011 Mar; 117(10):2891-900. PubMed ID: 21224467
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hes1 expression and CYLD repression are essential events downstream of Notch1 in T-cell leukemia.
    D'Altri T; Gonzalez J; Aifantis I; Espinosa L; Bigas A
    Cell Cycle; 2011 Apr; 10(7):1031-6. PubMed ID: 21389783
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells.
    Gerby B; Tremblay CS; Tremblay M; Rojas-Sutterlin S; Herblot S; Hébert J; Sauvageau G; Lemieux S; Lécuyer E; Veiga DF; Hoang T
    PLoS Genet; 2014 Dec; 10(12):e1004768. PubMed ID: 25522233
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment.
    Tian C; Zheng G; Cao Z; Li Q; Ju Z; Wang J; Yuan W; Cheng T
    Cell Cycle; 2013 Jan; 12(2):322-31. PubMed ID: 23255132
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44(+)/CD24(-/low) tumor-initiating subpopulation in basal-like breast cancer.
    So JY; Wahler J; Das Gupta S; Salerno DM; Maehr H; Uskokovic M; Suh N
    J Steroid Biochem Mol Biol; 2015 Apr; 148():111-21. PubMed ID: 25541438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
    Tatarek J; Cullion K; Ashworth T; Gerstein R; Aster JC; Kelliher MA
    Blood; 2011 Aug; 118(6):1579-90. PubMed ID: 21670468
    [TBL] [Abstract][Full Text] [Related]  

  • 14. T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.
    De Obaldia ME; Bell JJ; Wang X; Harly C; Yashiro-Ohtani Y; DeLong JH; Zlotoff DA; Sultana DA; Pear WS; Bhandoola A
    Nat Immunol; 2013 Dec; 14(12):1277-84. PubMed ID: 24185616
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hes1, a new target for interleukin 1beta in chondrocytes.
    Ottaviani S; Tahiri K; Frazier A; Hassaine ZN; Dumontier MF; Baschong W; Rannou F; Corvol MT; Savouret JF; Richette P
    Ann Rheum Dis; 2010 Aug; 69(8):1488-94. PubMed ID: 19914905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Membrane receptor-dependent Notch1/Hes1 activation by melatonin protects against myocardial ischemia-reperfusion injury: in vivo and in vitro studies.
    Yu L; Liang H; Lu Z; Zhao G; Zhai M; Yang Y; Yang J; Yi D; Chen W; Wang X; Duan W; Jin Z; Yu S
    J Pineal Res; 2015 Nov; 59(4):420-33. PubMed ID: 26308963
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Monoallelic
    Veiga DFT; Tremblay M; Gerby B; Herblot S; Haman A; Gendron P; Lemieux S; Zúñiga-Pflücker JC; Hébert J; Cohen JP; Hoang T
    Front Immunol; 2022; 13():867443. PubMed ID: 35401501
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes.
    Dudley DD; Wang HC; Sun XH
    PLoS One; 2009 Aug; 4(8):e6678. PubMed ID: 19688092
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
    Espinosa L; Cathelin S; D'Altri T; Trimarchi T; Statnikov A; Guiu J; Rodilla V; Inglés-Esteve J; Nomdedeu J; Bellosillo B; Besses C; Abdel-Wahab O; Kucine N; Sun SC; Song G; Mullighan CC; Levine RL; Rajewsky K; Aifantis I; Bigas A
    Cancer Cell; 2010 Sep; 18(3):268-81. PubMed ID: 20832754
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transient responses to NOTCH and TLX1/HOX11 inhibition in T-cell acute lymphoblastic leukemia/lymphoma.
    Rakowski LA; Lehotzky EA; Chiang MY
    PLoS One; 2011 Feb; 6(2):e16761. PubMed ID: 21326611
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.