BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

435 related articles for article (PubMed ID: 25785833)

  • 1. Knockdown of CDK2AP1 in primary human fibroblasts induces p53 dependent senescence.
    Alsayegh KN; Gadepalli VS; Iyer S; Rao RR
    PLoS One; 2015; 10(3):e0120782. PubMed ID: 25785833
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Knockdown of CDK2AP1 in human embryonic stem cells reduces the threshold of differentiation.
    Alsayegh KN; Sheridan SD; Iyer S; Rao RR
    PLoS One; 2018; 13(5):e0196817. PubMed ID: 29734353
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3.
    Hemmati PG; Müer A; Gillissen B; Overkamp T; Milojkovic A; Wendt J; Dörken B; Daniel PT
    J Mol Med (Berl); 2010 Jun; 88(6):609-22. PubMed ID: 20419447
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.
    Valente LJ; Gray DH; Michalak EM; Pinon-Hofbauer J; Egle A; Scott CL; Janic A; Strasser A
    Cell Rep; 2013 May; 3(5):1339-45. PubMed ID: 23665218
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase.
    Zemskova M; Lilly MB; Lin YW; Song JH; Kraft AS
    Mol Cancer Res; 2010 Aug; 8(8):1126-41. PubMed ID: 20647331
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cooperation between p21 and Akt is required for p53-dependent cellular senescence.
    Kim YY; Jee HJ; Um JH; Kim YM; Bae SS; Yun J
    Aging Cell; 2017 Oct; 16(5):1094-1103. PubMed ID: 28691365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation.
    Lentini L; Barra V; Schillaci T; Di Leonardo A
    J Cell Physiol; 2012 Sep; 227(9):3324-32. PubMed ID: 22170163
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells.
    Zuo S; Liu C; Wang J; Wang F; Xu W; Cui S; Yuan L; Chen X; Fan W; Cui M; Song G
    J Cancer Res Clin Oncol; 2012 Jun; 138(6):1045-55. PubMed ID: 22392074
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The ubiquitin ligase COP1 regulates cell cycle and apoptosis by affecting p53 function in human breast cancer cell lines.
    Ka WH; Cho SK; Chun BN; Byun SY; Ahn JC
    Breast Cancer; 2018 Sep; 25(5):529-538. PubMed ID: 29516369
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts.
    Chen QM; Liu J; Merrett JB
    Biochem J; 2000 Apr; 347(Pt 2):543-51. PubMed ID: 10749685
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Knockdown of MBP-1 in human foreskin fibroblasts induces p53-p21 dependent senescence.
    Ghosh AK; Kanda T; Steele R; Ray RB
    PLoS One; 2008; 3(10):e3384. PubMed ID: 18852884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interferon-gamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells.
    Kim KS; Kang KW; Seu YB; Baek SH; Kim JR
    Mech Ageing Dev; 2009 Mar; 130(3):179-88. PubMed ID: 19071156
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BS69 is involved in cellular senescence through the p53-p21Cip1 pathway.
    Zhang W; Chan HM; Gao Y; Poon R; Wu Z
    EMBO Rep; 2007 Oct; 8(10):952-8. PubMed ID: 17721438
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of p53 by Nutlin-3a, an antagonist of MDM2, induces apoptosis and cellular senescence in adult T-cell leukemia cells.
    Hasegawa H; Yamada Y; Iha H; Tsukasaki K; Nagai K; Atogami S; Sugahara K; Tsuruda K; Ishizaki A; Kamihira S
    Leukemia; 2009 Nov; 23(11):2090-101. PubMed ID: 19710698
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.
    Kortlever RM; Higgins PJ; Bernards R
    Nat Cell Biol; 2006 Aug; 8(8):877-84. PubMed ID: 16862142
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
    Liu W; Dai Q; Lu N; Wei L; Ha J; Rong J; Mu R; You Q; Li Z; Guo Q
    Biochem Cell Biol; 2011 Jun; 89(3):287-98. PubMed ID: 21491996
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.
    Javelaud D; Besancon F
    J Biol Chem; 2002 Oct; 277(40):37949-54. PubMed ID: 12151395
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oncomir miR-125b suppresses p14(ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer.
    Amir S; Ma AH; Shi XB; Xue L; Kung HJ; Devere White RW
    PLoS One; 2013; 8(4):e61064. PubMed ID: 23585871
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53.
    Heminger K; Markey M; Mpagi M; Berberich SJ
    Aging (Albany NY); 2009 Jan; 1(1):89-108. PubMed ID: 19946469
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Absence of p53-dependent apoptosis leads to UV radiation hypersensitivity, enhanced immunosuppression and cellular senescence.
    Tavana O; Benjamin CL; Puebla-Osorio N; Sang M; Ullrich SE; Ananthaswamy HN; Zhu C
    Cell Cycle; 2010 Aug; 9(16):3328-36. PubMed ID: 20703098
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.