BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

391 related articles for article (PubMed ID: 25790376)

  • 1. Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein.
    Kilpatrick K; Zeng Y; Hancock T; Segatori L
    PLoS One; 2015; 10(3):e0120819. PubMed ID: 25790376
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
    Rusmini P; Cortese K; Crippa V; Cristofani R; Cicardi ME; Ferrari V; Vezzoli G; Tedesco B; Meroni M; Messi E; Piccolella M; Galbiati M; Garrè M; Morelli E; Vaccari T; Poletti A
    Autophagy; 2019 Apr; 15(4):631-651. PubMed ID: 30335591
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2-Hydroxypropyl-β-cyclodextrin promotes transcription factor EB-mediated activation of autophagy: implications for therapy.
    Song W; Wang F; Lotfi P; Sardiello M; Segatori L
    J Biol Chem; 2014 Apr; 289(14):10211-22. PubMed ID: 24558044
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Iron promotes α-synuclein aggregation and transmission by inhibiting TFEB-mediated autophagosome-lysosome fusion.
    Xiao Y; Chen X; Huang S; Li G; Mo M; Zhang L; Chen C; Guo W; Zhou M; Wu Z; Cen L; Long S; Li S; Yang X; Qu S; Pei Z; Xu P
    J Neurochem; 2018 Apr; 145(1):34-50. PubMed ID: 29364516
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
    Decressac M; Mattsson B; Weikop P; Lundblad M; Jakobsson J; Björklund A
    Proc Natl Acad Sci U S A; 2013 May; 110(19):E1817-26. PubMed ID: 23610405
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TFEB regulates cellular labile iron and prevents ferroptosis in a TfR1-dependent manner.
    Chen L; Ma Y; Ma X; Liu L; Jv X; Li A; Shen Q; Jia W; Qu L; Shi L; Xie J
    Free Radic Biol Med; 2023 Nov; 208():445-457. PubMed ID: 37683766
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhancing the Astrocytic Clearance of Extracellular α-Synuclein Aggregates by Ginkgolides Attenuates Neural Cell Injury.
    Hua J; Yin N; Xu S; Chen Q; Tao T; Zhang J; Ding J; Fan Y; Hu G
    Cell Mol Neurobiol; 2019 Oct; 39(7):1017-1028. PubMed ID: 31165943
    [TBL] [Abstract][Full Text] [Related]  

  • 8. YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
    Xu Y; Ren J; He X; Chen H; Wei T; Feng W
    Autophagy; 2019 Jun; 15(6):1017-1030. PubMed ID: 30653408
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity.
    Pi H; Li M; Tian L; Yang Z; Yu Z; Zhou Z
    Sci Rep; 2017 Feb; 7():43466. PubMed ID: 28240313
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux.
    Pan B; Zhang H; Cui T; Wang X
    J Mol Cell Cardiol; 2017 Dec; 113():51-62. PubMed ID: 28993153
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5.
    Nezich CL; Wang C; Fogel AI; Youle RJ
    J Cell Biol; 2015 Aug; 210(3):435-50. PubMed ID: 26240184
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A SPLICS reporter reveals [Formula: see text]-synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation.
    Giamogante F; Barazzuol L; Maiorca F; Poggio E; Esposito A; Masato A; Napolitano G; Vagnoni A; Calì T; Brini M
    Nat Commun; 2024 Feb; 15(1):1516. PubMed ID: 38374070
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TFEB-mediated Enhancement of the Autophagy-lysosomal Pathway Dually Modulates the Process of Amyloid β-Protein Generation in Neurons.
    Yamamoto F; Taniguchi K; Mamada N; Tamaoka A; Kametani F; Lakshmana MK; Araki W
    Neuroscience; 2019 Mar; 402():11-22. PubMed ID: 30677488
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson's disease.
    Grassi D; Howard S; Zhou M; Diaz-Perez N; Urban NT; Guerrero-Given D; Kamasawa N; Volpicelli-Daley LA; LoGrasso P; Lasmézas CI
    Proc Natl Acad Sci U S A; 2018 Mar; 115(11):E2634-E2643. PubMed ID: 29487216
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases.
    Chen Y; Xu S; Wang N; Ma Q; Peng P; Yu Y; Zhang L; Ying Z; Wang H
    Neurotox Res; 2019 Jul; 36(1):108-116. PubMed ID: 30924108
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia.
    Bao J; Zheng L; Zhang Q; Li X; Zhang X; Li Z; Bai X; Zhang Z; Huo W; Zhao X; Shang S; Wang Q; Zhang C; Ji J
    Protein Cell; 2016 Jun; 7(6):417-33. PubMed ID: 27209302
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Cleaning Crew: The Pursuit of Autophagy in Parkinson's Disease.
    Parekh P; Sharma N; Gadepalli A; Shahane A; Sharma M; Khairnar A
    ACS Chem Neurosci; 2019 Sep; 10(9):3914-3926. PubMed ID: 31385687
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aneuploidy-induced cellular stresses limit autophagic degradation.
    Santaguida S; Vasile E; White E; Amon A
    Genes Dev; 2015 Oct; 29(19):2010-21. PubMed ID: 26404941
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Docetaxel enhances lysosomal function through TFEB activation.
    Zhang J; Wang J; Wong YK; Sun X; Chen Y; Wang L; Yang L; Lu L; Shen HM; Huang D
    Cell Death Dis; 2018 May; 9(6):614. PubMed ID: 29795139
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein.
    Tyson T; Senchuk M; Cooper JF; George S; Van Raamsdonk JM; Brundin P
    Sci Rep; 2017 Aug; 7(1):7506. PubMed ID: 28790319
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.