These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 25797502)

  • 1. Microwave-assisted synthesis, characterization and cytotoxic studies of novel estrogen receptor α ligands towards human breast cancer cells.
    Bharathkumar H; Mohan CD; Ananda H; Fuchs JE; Li F; Rangappa S; Surender M; Bulusu KC; Girish KS; Sethi G; Bender A; Basappa ; Rangappa KS
    Bioorg Med Chem Lett; 2015 Apr; 25(8):1804-1807. PubMed ID: 25797502
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In silico identification of novel inhibitors targeting the DNA-binding domain of the human estrogen receptor alpha.
    Cao H; Sun Y; Wang L; Pan Y; Li Z; Liang Y
    J Steroid Biochem Mol Biol; 2021 Oct; 213():105966. PubMed ID: 34416373
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α.
    Singh K; Munuganti RS; Leblanc E; Lin YL; Leung E; Lallous N; Butler M; Cherkasov A; Rennie PS
    Breast Cancer Res; 2015 Feb; 17(1):27. PubMed ID: 25848700
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of estrogen receptor alpha protein level and survival function by DBC-1.
    Trauernicht AM; Kim SJ; Kim NH; Boyer TG
    Mol Endocrinol; 2007 Jul; 21(7):1526-36. PubMed ID: 17473282
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dynamics-Based Discovery of Novel, Potent Benzoic Acid Derivatives as Orally Bioavailable Selective Estrogen Receptor Degraders for ERα+ Breast Cancer.
    Zhang X; Wang Y; Li X; Wu J; Zhao L; Li W; Liu J
    J Med Chem; 2021 Jun; 64(11):7575-7595. PubMed ID: 34056898
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of novel dual-acting modulators targeting both estrogen receptor α (ERα) and lysine-specific demethylase 1 (LSD1) for treatment of breast cancer.
    He M; Ning W; Hu Z; Huang J; Dong C; Zhou HB
    Eur J Med Chem; 2020 Jun; 195():112281. PubMed ID: 32283297
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ER alpha selective chromone, isoxazolylchromones, induces ROS-mediated cell death without autophagy.
    Kaushik S; Sanawar R; Lekshmi A; Chandrasekhar L; Nair M; Bhatnagar S; Santhoshkumar TR
    Chem Biol Drug Des; 2019 Jul; 94(1):1352-1367. PubMed ID: 31066219
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and biological evaluation of novel morpholinated isatin-quinoline hybrids as potent anti-breast cancer agents.
    Singh A; Kaur H; Arora S; Bedi PMS
    Arch Pharm (Weinheim); 2022 Feb; 355(2):e2100368. PubMed ID: 34783073
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, biological evaluation and molecular docking studies of novel 3-aryl-4-anilino-2H-chromen-2-one derivatives targeting ERα as anti-breast cancer agents.
    Luo G; Chen M; Lyu W; Zhao R; Xu Q; You Q; Xiang H
    Bioorg Med Chem Lett; 2017 Jun; 27(12):2668-2673. PubMed ID: 28460819
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of 3-aryl-quinolin derivatives as anti-breast cancer agents targeting ERα and VEGFR-2.
    Li X; Wu C; Lin X; Cai X; Liu L; Luo G; You Q; Xiang H
    Eur J Med Chem; 2019 Jan; 161():445-455. PubMed ID: 30384047
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular mechanisms of selective estrogen receptor modulator activity in human breast cancer cells: identification of novel nuclear cofactors of antiestrogen-ERα complexes by interaction proteomics.
    Cirillo F; Nassa G; Tarallo R; Stellato C; De Filippo MR; Ambrosino C; Baumann M; Nyman TA; Weisz A
    J Proteome Res; 2013 Jan; 12(1):421-31. PubMed ID: 23170835
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selection of a GPER1 Ligand via Ligand-based Virtual Screening Coupled to Molecular Dynamics Simulations and Its Anti-proliferative Effects on Breast Cancer Cells.
    Martínez-Muñoz A; Prestegui-Martel B; Méndez-Luna D; Fragoso-Vázquez MJ; García-Sánchez JR; Bello M; Martínez-Archundia M; Chávez-Blanco A; Dueñas-González A; Mendoza-Lujambio I; Trujillo-Ferrara J; Correa-Basurto J
    Anticancer Agents Med Chem; 2018; 18(11):1629-1638. PubMed ID: 29745344
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In silico Molecular Modelling of Selected Natural Ligands and their Binding Features with Estrogen Receptor Alpha.
    Maruthanila VL; Elancheran R; Roy NK; Bhattacharya A; Kunnumakkara AB; Kabilan S; Kotoky J
    Curr Comput Aided Drug Des; 2019; 15(1):89-96. PubMed ID: 30306879
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phenytoin is an estrogen receptor α-selective modulator that interacts with helix 12.
    Fadiel A; Song J; Tivon D; Hamza A; Cardozo T; Naftolin F
    Reprod Sci; 2015 Feb; 22(2):146-55. PubMed ID: 25258361
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells.
    Caruso JA; Campana R; Wei C; Su CH; Hanks AM; Bornmann WG; Keyomarsi K
    Cell Cycle; 2014; 13(16):2587-99. PubMed ID: 25486199
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors α- and β-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft.
    Saxena R; Fatima I; Chandra V; Blesson CS; Kharkwal G; Hussain MK; Hajela K; Roy BG; Dwivedi A
    Steroids; 2013 Nov; 78(11):1071-86. PubMed ID: 23891847
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells.
    Stender JD; Nwachukwu JC; Kastrati I; Kim Y; Strid T; Yakir M; Srinivasan S; Nowak J; Izard T; Rangarajan ES; Carlson KE; Katzenellenbogen JA; Yao XQ; Grant BJ; Leong HS; Lin CY; Frasor J; Nettles KW; Glass CK
    Mol Cell; 2017 Mar; 65(6):1122-1135.e5. PubMed ID: 28306507
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activity of the antiestrogenic cajanin stilbene acid towards breast cancer.
    Fu Y; Kadioglu O; Wiench B; Wei Z; Wang W; Luo M; Yang X; Gu C; Zu Y; Efferth T
    J Nutr Biochem; 2015 Nov; 26(11):1273-82. PubMed ID: 26365581
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity.
    Luo G; Tang Z; Lao K; Li X; You Q; Xiang H
    Eur J Med Chem; 2018 Apr; 150():783-795. PubMed ID: 29587221
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 1,2,4-Triazine Sulfonamides: Synthesis by Sulfenamide Intermediates, In Vitro Anticancer Screening, Structural Characterization, and Molecular Docking Study.
    Branowska D; Karczmarzyk Z; Wolińska E; Wysocki W; Morawiak M; Urbańczyk-Lipkowska Z; Bielawska A; Bielawski K
    Molecules; 2020 May; 25(10):. PubMed ID: 32429377
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.