BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1100 related articles for article (PubMed ID: 25799992)

  • 1. REV7 counteracts DNA double-strand break resection and affects PARP inhibition.
    Xu G; Chapman JR; Brandsma I; Yuan J; Mistrik M; Bouwman P; Bartkova J; Gogola E; Warmerdam D; Barazas M; Jaspers JE; Watanabe K; Pieterse M; Kersbergen A; Sol W; Celie PHN; Schouten PC; van den Broek B; Salman A; Nieuwland M; de Rink I; de Ronde J; Jalink K; Boulton SJ; Chen J; van Gent DC; Bartek J; Jonkers J; Borst P; Rottenberg S
    Nature; 2015 May; 521(7553):541-544. PubMed ID: 25799992
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.
    Gupta R; Somyajit K; Narita T; Maskey E; Stanlie A; Kremer M; Typas D; Lammers M; Mailand N; Nussenzweig A; Lukas J; Choudhary C
    Cell; 2018 May; 173(4):972-988.e23. PubMed ID: 29656893
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.
    Boersma V; Moatti N; Segura-Bayona S; Peuscher MH; van der Torre J; Wevers BA; Orthwein A; Durocher D; Jacobs JJL
    Nature; 2015 May; 521(7553):537-540. PubMed ID: 25799990
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
    Ghezraoui H; Oliveira C; Becker JR; Bilham K; Moralli D; Anzilotti C; Fischer R; Deobagkar-Lele M; Sanchiz-Calvo M; Fueyo-Marcos E; Bonham S; Kessler BM; Rottenberg S; Cornall RJ; Green CM; Chapman JR
    Nature; 2018 Aug; 560(7716):122-127. PubMed ID: 30046110
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.
    Dev H; Chiang TW; Lescale C; de Krijger I; Martin AG; Pilger D; Coates J; Sczaniecka-Clift M; Wei W; Ostermaier M; Herzog M; Lam J; Shea A; Demir M; Wu Q; Yang F; Fu B; Lai Z; Balmus G; Belotserkovskaya R; Serra V; O'Connor MJ; Bruna A; Beli P; Pellegrini L; Caldas C; Deriano L; Jacobs JJL; Galanty Y; Jackson SP
    Nat Cell Biol; 2018 Aug; 20(8):954-965. PubMed ID: 30022119
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4.
    Pfeiffer A; Luijsterburg MS; Acs K; Wiegant WW; Helfricht A; Herzog LK; Minoia M; Böttcher C; Salomons FA; van Attikum H; Dantuma NP
    EMBO J; 2017 Apr; 36(8):1066-1083. PubMed ID: 28275011
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CHAMP1-POGZ counteracts the inhibitory effect of 53BP1 on homologous recombination and affects PARP inhibitor resistance.
    Fujita H; Ikeda M; Ui A; Ouchi Y; Mikami Y; Kanno SI; Yasui A; Tanaka K
    Oncogene; 2022 May; 41(19):2706-2718. PubMed ID: 35393543
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks.
    Lee KY; Im JS; Shibata E; Dutta A
    Mol Cell; 2017 Oct; 68(1):61-75.e5. PubMed ID: 28943310
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.
    Findlay S; Heath J; Luo VM; Malina A; Morin T; Coulombe Y; Djerir B; Li Z; Samiei A; Simo-Cheyou E; Karam M; Bagci H; Rahat D; Grapton D; Lavoie EG; Dove C; Khaled H; Kuasne H; Mann KK; Klein KO; Greenwood CM; Tabach Y; Park M; Côté JF; Masson JY; Maréchal A; Orthwein A
    EMBO J; 2018 Sep; 37(18):. PubMed ID: 30154076
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.
    Noon AT; Shibata A; Rief N; Löbrich M; Stewart GS; Jeggo PA; Goodarzi AA
    Nat Cell Biol; 2010 Feb; 12(2):177-84. PubMed ID: 20081839
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination.
    Becker JR; Clifford G; Bonnet C; Groth A; Wilson MD; Chapman JR
    Nature; 2021 Aug; 596(7872):433-437. PubMed ID: 34321663
    [TBL] [Abstract][Full Text] [Related]  

  • 12. H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.
    Simonetta M; de Krijger I; Serrat J; Moatti N; Fortunato D; Hoekman L; Bleijerveld OB; Altelaar AFM; Jacobs JJL
    Cell Cycle; 2018; 17(1):124-136. PubMed ID: 29160738
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.
    Henriksson S; Rassoolzadeh H; Hedström E; Coucoravas C; Julner A; Goldstein M; Imreh G; Zhivotovsky B; Kastan MB; Helleday T; Farnebo M
    Genes Dev; 2014 Dec; 28(24):2726-38. PubMed ID: 25512560
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CtIP-mediated resection is essential for viability and can operate independently of BRCA1.
    Polato F; Callen E; Wong N; Faryabi R; Bunting S; Chen HT; Kozak M; Kruhlak MJ; Reczek CR; Lee WH; Ludwig T; Baer R; Feigenbaum L; Jackson S; Nussenzweig A
    J Exp Med; 2014 Jun; 211(6):1027-36. PubMed ID: 24842372
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining.
    Zong D; Callén E; Pegoraro G; Lukas C; Lukas J; Nussenzweig A
    Nucleic Acids Res; 2015 May; 43(10):4950-61. PubMed ID: 25916843
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The dystonia gene THAP1 controls DNA double-strand break repair choice.
    Shinoda K; Zong D; Callen E; Wu W; Dumitrache LC; Belinky F; Chari R; Wong N; Ishikawa M; Stanlie A; Multhaupt-Buell T; Sharma N; Ozelius L; Ehrlich M; McKinnon PJ; Nussenzweig A
    Mol Cell; 2021 Jun; 81(12):2611-2624.e10. PubMed ID: 33857404
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.
    Nakada S; Yonamine RM; Matsuo K
    Cancer Res; 2012 Oct; 72(19):4974-83. PubMed ID: 22865450
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.
    Marteijn JA; Bekker-Jensen S; Mailand N; Lans H; Schwertman P; Gourdin AM; Dantuma NP; Lukas J; Vermeulen W
    J Cell Biol; 2009 Sep; 186(6):835-47. PubMed ID: 19797077
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase.
    Kolas NK; Chapman JR; Nakada S; Ylanko J; Chahwan R; Sweeney FD; Panier S; Mendez M; Wildenhain J; Thomson TM; Pelletier L; Jackson SP; Durocher D
    Science; 2007 Dec; 318(5856):1637-40. PubMed ID: 18006705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors.
    Peng Y; Liao Q; Tan W; Peng C; Hu Z; Chen Y; Li Z; Li J; Zhen B; Zhu W; Li X; Yao Y; Song Q; Liu C; Qi X; He F; Pei H
    Nat Commun; 2019 Mar; 10(1):1224. PubMed ID: 30874560
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 55.