304 related articles for article (PubMed ID: 25807300)
1. (Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies.
D'Ascenzio M; Chimenti P; Gidaro MC; De Monte C; De Vita D; Granese A; Scipione L; Di Santo R; Costa G; Alcaro S; Yáñez M; Carradori S
J Enzyme Inhib Med Chem; 2015 Dec; 30(6):908-19. PubMed ID: 25807300
[TBL] [Abstract][Full Text] [Related]
2. 4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis.
Secci D; Carradori S; Petzer A; Guglielmi P; D'Ascenzio M; Chimenti P; Bagetta D; Alcaro S; Zengin G; Petzer JP; Ortuso F
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):597-612. PubMed ID: 30727777
[TBL] [Abstract][Full Text] [Related]
3. Exploring 4-substituted-2-thiazolylhydrazones from 2-, 3-, and 4-acetylpyridine as selective and reversible hMAO-B inhibitors.
Chimenti P; Petzer A; Carradori S; D'Ascenzio M; Silvestri R; Alcaro S; Ortuso F; Petzer JP; Secci D
Eur J Med Chem; 2013 Aug; 66():221-7. PubMed ID: 23807114
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.
Chimenti F; Secci D; Bolasco A; Chimenti P; Granese A; Carradori S; Maccioni E; Cardia MC; Yáñez M; Orallo F; Alcaro S; Ortuso F; Cirilli R; Ferretti R; Distinto S; Kirchmair J; Langer T
Bioorg Med Chem; 2010 Jul; 18(14):5063-70. PubMed ID: 20579890
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of some novel hydrazone and 2-pyrazoline derivatives: monoamine oxidase inhibitory activities and docking studies.
Evranos-Aksöz B; Yabanoğlu-Çiftçi S; Uçar G; Yelekçi K; Ertan R
Bioorg Med Chem Lett; 2014 Aug; 24(15):3278-84. PubMed ID: 24986657
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and biochemical evaluation of novel multi-target inhibitors as potential anti-Parkinson agents.
Carradori S; Ortuso F; Petzer A; Bagetta D; De Monte C; Secci D; De Vita D; Guglielmi P; Zengin G; Aktumsek A; Alcaro S; Petzer JP
Eur J Med Chem; 2018 Jan; 143():1543-1552. PubMed ID: 29126727
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, and pharmacological evaluation of 2-amino-5-nitrothiazole derived semicarbazones as dual inhibitors of monoamine oxidase and cholinesterase: effect of the size of aryl binding site.
Tripathi RKP; M Sasi V; Gupta SK; Krishnamurthy S; Ayyannan SR
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):37-57. PubMed ID: 29098902
[TBL] [Abstract][Full Text] [Related]
8. Recent advances in the development of selective human MAO-B inhibitors: (hetero)arylidene-(4-substituted-thiazol-2-yl)hydrazines.
Secci D; Bolasco A; Carradori S; D'Ascenzio M; Nescatelli R; Yáñez M
Eur J Med Chem; 2012 Dec; 58():405-17. PubMed ID: 23153812
[TBL] [Abstract][Full Text] [Related]
9. Benzimidazole-derived carbohydrazones as dual monoamine oxidases and acetylcholinesterase inhibitors: design, synthesis, and evaluation.
Kumar S; Jaiswal S; Gupta SK; Ayyannan SR
J Biomol Struct Dyn; 2024 Jun; 42(9):4710-4729. PubMed ID: 37345530
[TBL] [Abstract][Full Text] [Related]
10. Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors.
D'Ascenzio M; Carradori S; Secci D; Mannina L; Sobolev AP; De Monte C; Cirilli R; Yáñez M; Alcaro S; Ortuso F
Bioorg Med Chem; 2014 May; 22(10):2887-95. PubMed ID: 24746464
[TBL] [Abstract][Full Text] [Related]
11. Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents.
Pisani L; Farina R; Catto M; Iacobazzi RM; Nicolotti O; Cellamare S; Mangiatordi GF; Denora N; Soto-Otero R; Siragusa L; Altomare CD; Carotti A
J Med Chem; 2016 Jul; 59(14):6791-806. PubMed ID: 27347731
[TBL] [Abstract][Full Text] [Related]
12. MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains.
Can ÖD; Osmaniye D; Demir Özkay Ü; Sağlık BN; Levent S; Ilgın S; Baysal M; Özkay Y; Kaplancıklı ZA
Eur J Med Chem; 2017 May; 131():92-106. PubMed ID: 28301816
[TBL] [Abstract][Full Text] [Related]
13. Sulfonyl thioureas with a benzo[d]thiazole ring as dual acetylcholinesterase/butyrylcholinesterase and human monoamine oxidase A and B inhibitors: An in vitro and in silico study.
Dinh Thanh N; Son Hai D; Ngoc Toan V; Thi Kim Van H; Thi Kim Giang N; Minh Tri N
Arch Pharm (Weinheim); 2024 May; 357(5):e2300557. PubMed ID: 38321839
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B.
Distinto S; Yáñez M; Alcaro S; Cardia MC; Gaspari M; Sanna ML; Meleddu R; Ortuso F; Kirchmair J; Markt P; Bolasco A; Wolber G; Secci D; Maccioni E
Eur J Med Chem; 2012 Feb; 48():284-95. PubMed ID: 22222137
[TBL] [Abstract][Full Text] [Related]
15. Dual functional cholinesterase and MAO inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of homoisoflavonoid derivatives.
Wang Y; Sun Y; Guo Y; Wang Z; Huang L; Li X
J Enzyme Inhib Med Chem; 2016; 31(3):389-97. PubMed ID: 25798687
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and selective human monoamine oxidase B inhibition of heterocyclic hybrids based on hydrazine and thiazole scaffolds.
Carradori S; D'Ascenzio M; De Monte C; Secci D; Yáñez M
Arch Pharm (Weinheim); 2013 Jan; 346(1):17-22. PubMed ID: 23065686
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Sang Z; Pan W; Wang K; Ma Q; Yu L; Liu W
Bioorg Med Chem; 2017 Jun; 25(12):3006-3017. PubMed ID: 28487125
[TBL] [Abstract][Full Text] [Related]
18. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.
Samadi A; de los Ríos C; Bolea I; Chioua M; Iriepa I; Moraleda I; Bartolini M; Andrisano V; Gálvez E; Valderas C; Unzeta M; Marco-Contelles J
Eur J Med Chem; 2012 Jun; 52():251-62. PubMed ID: 22503231
[TBL] [Abstract][Full Text] [Related]
19. Exploration of a Library of 3,4-(Methylenedioxy)aniline-Derived Semicarbazones as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase: Design, Synthesis, and Evaluation.
Tripathi RK; Rai GK; Ayyannan SR
ChemMedChem; 2016 Jun; 11(11):1145-60. PubMed ID: 27135466
[TBL] [Abstract][Full Text] [Related]
20. Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors.
Chimenti F; Bolasco A; Secci D; Chimenti P; Granese A; Carradori S; Yáñez M; Orallo F; Ortuso F; Alcaro S
Bioorg Med Chem; 2010 Aug; 18(15):5715-23. PubMed ID: 20615716
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]