BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

421 related articles for article (PubMed ID: 25809665)

  • 1. Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing.
    Depping R; Jelkmann W; Kosyna FK
    J Mol Med (Berl); 2015 Jun; 93(6):599-608. PubMed ID: 25809665
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling.
    Pientka FK; Hu J; Schindler SG; Brix B; Thiel A; Jöhren O; Fandrey J; Berchner-Pfannschmidt U; Depping R
    J Cell Sci; 2012 Nov; 125(Pt 21):5168-76. PubMed ID: 22946054
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The importin α/β-specific inhibitor Ivermectin affects HIF-dependent hypoxia response pathways.
    Kosyna FK; Nagel M; Kluxen L; Kraushaar K; Depping R
    Biol Chem; 2015 Dec; 396(12):1357-67. PubMed ID: 26351913
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2.
    Steinhoff A; Pientka FK; Möckel S; Kettelhake A; Hartmann E; Köhler M; Depping R
    Biochem Biophys Res Commun; 2009 Oct; 387(4):705-11. PubMed ID: 19631610
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of the intracellular localization of HIF-prolyl hydroxylases.
    Yasumoto K; Kowata Y; Yoshida A; Torii S; Sogawa K
    Biochim Biophys Acta; 2009 May; 1793(5):792-7. PubMed ID: 19339211
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-inducible factor 1 (HIF-1) pathway.
    Semenza GL
    Sci STKE; 2007 Oct; 2007(407):cm8. PubMed ID: 17925579
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
    Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
    EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7.
    Chachami G; Paraskeva E; Mingot JM; Braliou GG; Görlich D; Simos G
    Biochem Biophys Res Commun; 2009 Dec; 390(2):235-40. PubMed ID: 19788888
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
    Hewitson KS; Schofield CJ; Ratcliffe PJ
    Methods Enzymol; 2007; 435():25-42. PubMed ID: 17998047
    [TBL] [Abstract][Full Text] [Related]  

  • 11. von Hippel-Lindau protein adjusts oxygen sensing of the FIH asparaginyl hydroxylase.
    Li SH; Chun YS; Lim JH; Huang LE; Park JW
    Int J Biochem Cell Biol; 2011 May; 43(5):795-804. PubMed ID: 21316481
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
    Mole DR; Maxwell PH; Pugh CW; Ratcliffe PJ
    IUBMB Life; 2001 Jul; 52(1-2):43-7. PubMed ID: 11795592
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway.
    Depping R; Steinhoff A; Schindler SG; Friedrich B; Fagerlund R; Metzen E; Hartmann E; Köhler M
    Biochim Biophys Acta; 2008 Mar; 1783(3):394-404. PubMed ID: 18187047
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein.
    Groulx I; Lee S
    Mol Cell Biol; 2002 Aug; 22(15):5319-36. PubMed ID: 12101228
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HIF hydroxylation and cellular oxygen sensing.
    Metzen E; Ratcliffe PJ
    Biol Chem; 2004; 385(3-4):223-30. PubMed ID: 15134335
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
    Strowitzki MJ; Cummins EP; Taylor CT
    Cells; 2019 Apr; 8(5):. PubMed ID: 31035491
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo.
    Minamishima YA; Moslehi J; Padera RF; Bronson RT; Liao R; Kaelin WG
    Mol Cell Biol; 2009 Nov; 29(21):5729-41. PubMed ID: 19720742
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
    Aprelikova O; Chandramouli GV; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
    J Cell Biochem; 2004 Jun; 92(3):491-501. PubMed ID: 15156561
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
    Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Bürgel T; Jelkmann W; Acker H; Fandrey J
    J Cell Sci; 2003 Apr; 116(Pt 7):1319-26. PubMed ID: 12615973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.
    Tarhonskaya H; Hardy AP; Howe EA; Loik ND; Kramer HB; McCullagh JS; Schofield CJ; Flashman E
    J Biol Chem; 2015 Aug; 290(32):19726-42. PubMed ID: 26112411
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.