323 related articles for article (PubMed ID: 25810038)
1. The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.
Natalicchio A; Tortosa F; Labarbuta R; Biondi G; Marrano N; Carchia E; Leonardini A; Cignarelli A; Bugliani M; Marchetti P; Fadini GP; Giorgio M; Avogaro A; Perrini S; Laviola L; Giorgino F
Diabetologia; 2015 Jun; 58(6):1260-71. PubMed ID: 25810038
[TBL] [Abstract][Full Text] [Related]
2. Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.
Vikram A; Kim YR; Kumar S; Naqvi A; Hoffman TA; Kumar A; Miller FJ; Kim CS; Irani K
Arterioscler Thromb Vasc Biol; 2014 Oct; 34(10):2301-9. PubMed ID: 25147340
[TBL] [Abstract][Full Text] [Related]
3. TNFα signals via p66(Shc) to induce E-Selectin, promote leukocyte transmigration and enhance permeability in human endothelial cells.
Laviola L; Orlando MR; Incalza MA; Caccioppoli C; Melchiorre M; Leonardini A; Cignarelli A; Tortosa F; Labarbuta R; Martemucci S; Pacelli C; Cocco T; Perrini S; Natalicchio A; Giorgino F
PLoS One; 2013; 8(12):e81930. PubMed ID: 24349153
[TBL] [Abstract][Full Text] [Related]
4. p66(Shc)-induced redox changes drive endothelial insulin resistance.
Paneni F; Costantino S; Cosentino F
Atherosclerosis; 2014 Oct; 236(2):426-9. PubMed ID: 25150941
[TBL] [Abstract][Full Text] [Related]
5. D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc.
Sakao K; Singh SV
J Cell Biochem; 2012 Feb; 113(2):599-610. PubMed ID: 21956685
[TBL] [Abstract][Full Text] [Related]
6. p66Shc-generated oxidative signal promotes fat accumulation.
Berniakovich I; Trinei M; Stendardo M; Migliaccio E; Minucci S; Bernardi P; Pelicci PG; Giorgio M
J Biol Chem; 2008 Dec; 283(49):34283-93. PubMed ID: 18838380
[TBL] [Abstract][Full Text] [Related]
7. Downregulated adaptor protein p66(Shc) mitigates autophagy process by low nutrient and enhances apoptotic resistance in human lung adenocarcinoma A549 cells.
Zheng Z; Yang J; Zhao D; Gao D; Yan X; Yao Z; Liu Z; Ma Z
FEBS J; 2013 Sep; 280(18):4522-30. PubMed ID: 23815759
[TBL] [Abstract][Full Text] [Related]
8. The silence of p66(Shc) in HCT8 cells inhibits the viability via PI3K/AKT/Mdm-2/p53 signaling pathway.
Zhang L; Zhu S; Shi X; Sha W
Int J Clin Exp Pathol; 2015; 8(8):9097-104. PubMed ID: 26464652
[TBL] [Abstract][Full Text] [Related]
9. Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens.
Almeida M; Han L; Ambrogini E; Bartell SM; Manolagas SC
Mol Endocrinol; 2010 Oct; 24(10):2030-7. PubMed ID: 20685851
[TBL] [Abstract][Full Text] [Related]
10. Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells.
Shi Y; Cosentino F; Camici GG; Akhmedov A; Vanhoutte PM; Tanner FC; Lüscher TF
Arterioscler Thromb Vasc Biol; 2011 Sep; 31(9):2090-7. PubMed ID: 21817106
[TBL] [Abstract][Full Text] [Related]
11. p66(Shc) gene has a pro-apoptotic role in human cell lines and it is activated by a p53-independent pathway.
Tiberi L; Faisal A; Rossi M; Di Tella L; Franceschi C; Salvioli S
Biochem Biophys Res Commun; 2006 Apr; 342(2):503-8. PubMed ID: 16487929
[TBL] [Abstract][Full Text] [Related]
12. p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells.
Xiao D; Singh SV
Cancer Res; 2010 Apr; 70(8):3150-8. PubMed ID: 20354186
[TBL] [Abstract][Full Text] [Related]
13. p53-p66(shc)/miR-21-Sod2 signaling is critical for the inhibitory effect of betulinic acid on hepatocellular carcinoma.
Yang J; Qiu B; Li X; Zhang H; Liu W
Toxicol Lett; 2015 Nov; 238(3):1-10. PubMed ID: 26222667
[TBL] [Abstract][Full Text] [Related]
14. Selective inhibition of protein kinase C β2 attenuates the adaptor P66 Shc-mediated intestinal ischemia-reperfusion injury.
Chen Z; Wang G; Zhai X; Hu Y; Gao D; Ma L; Yao J; Tian X
Cell Death Dis; 2014 Apr; 5(4):e1164. PubMed ID: 24722289
[TBL] [Abstract][Full Text] [Related]
15. Long-Term Exposure of Pancreatic β-Cells to Palmitate Results in SREBP-1C-Dependent Decreases in GLP-1 Receptor Signaling via CREB and AKT and Insulin Secretory Response.
Natalicchio A; Biondi G; Marrano N; Labarbuta R; Tortosa F; Spagnuolo R; D'Oria R; Carchia E; Leonardini A; Cignarelli A; Perrini S; Laviola L; Giorgino F
Endocrinology; 2016 Jun; 157(6):2243-58. PubMed ID: 27035653
[TBL] [Abstract][Full Text] [Related]
16. miR214-regulated p53-NOX4/p66shc pathway plays a crucial role in the protective effect of Ginkgolide B against cisplatin-induced cytotoxicity in HEI-OC1 cells.
Ma W; Li J; Hu J; Cheng Y; Wang J; Zhang X; Xu M
Chem Biol Interact; 2016 Feb; 245():72-81. PubMed ID: 26768586
[TBL] [Abstract][Full Text] [Related]
17. Adaptor protein p66(Shc) mediates hypertension-associated, cyclic stretch-dependent, endothelial damage.
Spescha RD; Glanzmann M; Simic B; Witassek F; Keller S; Akhmedov A; Tanner FC; Lüscher TF; Camici GG
Hypertension; 2014 Aug; 64(2):347-53. PubMed ID: 24842918
[TBL] [Abstract][Full Text] [Related]
18. Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress.
Camici GG; Schiavoni M; Francia P; Bachschmid M; Martin-Padura I; Hersberger M; Tanner FC; Pelicci P; Volpe M; Anversa P; Lüscher TF; Cosentino F
Proc Natl Acad Sci U S A; 2007 Mar; 104(12):5217-22. PubMed ID: 17360381
[TBL] [Abstract][Full Text] [Related]
19. Post-ischaemic silencing of p66Shc reduces ischaemia/reperfusion brain injury and its expression correlates to clinical outcome in stroke.
Spescha RD; Klohs J; Semerano A; Giacalone G; Derungs RS; Reiner MF; Rodriguez Gutierrez D; Mendez-Carmona N; Glanzmann M; Savarese G; Kränkel N; Akhmedov A; Keller S; Mocharla P; Kaufmann MR; Wenger RH; Vogel J; Kulic L; Nitsch RM; Beer JH; Peruzzotti-Jametti L; Sessa M; Lüscher TF; Camici GG
Eur Heart J; 2015 Jul; 36(25):1590-600. PubMed ID: 25904764
[TBL] [Abstract][Full Text] [Related]
20. The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury.
Carpi A; Menabò R; Kaludercic N; Pelicci P; Di Lisa F; Giorgio M
Biochim Biophys Acta; 2009 Jul; 1787(7):774-80. PubMed ID: 19362067
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
