BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

343 related articles for article (PubMed ID: 25811481)

  • 1. SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase.
    Zhang Y; Bharathi SS; Rardin MJ; Uppala R; Verdin E; Gibson BW; Goetzman ES
    PLoS One; 2015; 10(3):e0122297. PubMed ID: 25811481
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.
    Bharathi SS; Zhang Y; Mohsen AW; Uppala R; Balasubramani M; Schreiber E; Uechi G; Beck ME; Rardin MJ; Vockley J; Verdin E; Gibson BW; Hirschey MD; Goetzman ES
    J Biol Chem; 2013 Nov; 288(47):33837-33847. PubMed ID: 24121500
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain.
    Zhang Y; Bharathi SS; Rardin MJ; Lu J; Maringer KV; Sims-Lucas S; Prochownik EV; Gibson BW; Goetzman ES
    J Biol Chem; 2017 Jun; 292(24):10239-10249. PubMed ID: 28458255
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.
    Schlicker C; Gertz M; Papatheodorou P; Kachholz B; Becker CF; Steegborn C
    J Mol Biol; 2008 Oct; 382(3):790-801. PubMed ID: 18680753
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The enzyme activity of mitochondrial trifunctional protein is not altered by lysine acetylation or lysine succinylation.
    Zhang Y; Goetzman E
    PLoS One; 2021; 16(10):e0256619. PubMed ID: 34644302
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Catalytic and FAD-binding residues of mitochondrial very long chain acyl-coenzyme A dehydrogenase.
    Souri M; Aoyama T; Cox GF; Hashimoto T
    J Biol Chem; 1998 Feb; 273(7):4227-31. PubMed ID: 9461620
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
    Hirschey MD; Shimazu T; Goetzman E; Jing E; Schwer B; Lombard DB; Grueter CA; Harris C; Biddinger S; Ilkayeva OR; Stevens RD; Li Y; Saha AK; Ruderman NB; Bain JR; Newgard CB; Farese RV; Alt FW; Kahn CR; Verdin E
    Nature; 2010 Mar; 464(7285):121-5. PubMed ID: 20203611
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The ɛ-Amino Group of Protein Lysine Residues Is Highly Susceptible to Nonenzymatic Acylation by Several Physiological Acyl-CoA Thioesters.
    Simic Z; Weiwad M; Schierhorn A; Steegborn C; Schutkowski M
    Chembiochem; 2015 Nov; 16(16):2337-47. PubMed ID: 26382620
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PGC-1α Promotes Ureagenesis in Mouse Periportal Hepatocytes through SIRT3 and SIRT5 in Response to Glucagon.
    Li L; Zhang P; Bao Z; Wang T; Liu S; Huang F
    Sci Rep; 2016 Apr; 6():24156. PubMed ID: 27052737
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3.
    Kwon S; Seok S; Yau P; Li X; Kemper B; Kemper JK
    J Biol Chem; 2017 Oct; 292(42):17312-17323. PubMed ID: 28808064
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.
    Alrob OA; Sankaralingam S; Ma C; Wagg CS; Fillmore N; Jaswal JS; Sack MN; Lehner R; Gupta MP; Michelakis ED; Padwal RS; Johnstone DE; Sharma AM; Lopaschuk GD
    Cardiovasc Res; 2014 Sep; 103(4):485-97. PubMed ID: 24966184
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.
    Sadhukhan S; Liu X; Ryu D; Nelson OD; Stupinski JA; Li Z; Chen W; Zhang S; Weiss RS; Locasale JW; Auwerx J; Lin H
    Proc Natl Acad Sci U S A; 2016 Apr; 113(16):4320-5. PubMed ID: 27051063
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses.
    Heinonen T; Ciarlo E; Le Roy D; Roger T
    Front Immunol; 2019; 10():2341. PubMed ID: 31632409
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease.
    Newman JC; He W; Verdin E
    J Biol Chem; 2012 Dec; 287(51):42436-43. PubMed ID: 23086951
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism.
    Ali HR; Assiri MA; Harris PS; Michel CR; Yun Y; Marentette JO; Huynh FK; Orlicky DJ; Shearn CT; Saba LM; Reisdorph R; Reisdorph N; Hirschey MD; Fritz KS
    J Proteome Res; 2019 Apr; 18(4):1513-1531. PubMed ID: 30644754
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rat very-long-chain acyl-CoA dehydrogenase, a novel mitochondrial acyl-CoA dehydrogenase gene product, is a rate-limiting enzyme in long-chain fatty acid beta-oxidation system. cDNA and deduced amino acid sequence and distinct specificities of the cDNA-expressed protein.
    Aoyama T; Ueno I; Kamijo T; Hashimoto T
    J Biol Chem; 1994 Jul; 269(29):19088-94. PubMed ID: 8034667
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
    Xu X; Zhu XP; Bai JY; Xia P; Li Y; Lu Y; Li XY; Gao X
    FASEB J; 2019 Jun; 33(6):7289-7300. PubMed ID: 30848932
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The absence of SIRT3 and SIRT5 promotes the acetylation of lens proteins and improves the chaperone activity of α-crystallin in mouse lenses.
    Nandi SK; Nahomi RB; Harris PS; Michel CR; Fritz KS; Nagaraj RH
    Exp Eye Res; 2019 May; 182():1-9. PubMed ID: 30849386
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.
    Goetzman ES; Bharathi SS; Zhang Y; Zhao XJ; Dobrowolski SF; Peasley K; Sims-Lucas S; Monga SP
    Sci Rep; 2020 Oct; 10(1):18367. PubMed ID: 33110171
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase.
    McAndrew RP; Wang Y; Mohsen AW; He M; Vockley J; Kim JJ
    J Biol Chem; 2008 Apr; 283(14):9435-43. PubMed ID: 18227065
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.