These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 25811761)

  • 1. Variations in the binding pocket of an inhibitor of the bacterial division protein FtsZ across genotypes and species.
    Miguel A; Hsin J; Liu T; Tang G; Altman RB; Huang KC
    PLoS Comput Biol; 2015 Mar; 11(3):e1004117. PubMed ID: 25811761
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity.
    Elsen NL; Lu J; Parthasarathy G; Reid JC; Sharma S; Soisson SM; Lumb KJ
    J Am Chem Soc; 2012 Aug; 134(30):12342-5. PubMed ID: 22793495
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An inhibitor of FtsZ with potent and selective anti-staphylococcal activity.
    Haydon DJ; Stokes NR; Ure R; Galbraith G; Bennett JM; Brown DR; Baker PJ; Barynin VV; Rice DW; Sedelnikova SE; Heal JR; Sheridan JM; Aiwale ST; Chauhan PK; Srivastava A; Taneja A; Collins I; Errington J; Czaplewski LG
    Science; 2008 Sep; 321(5896):1673-5. PubMed ID: 18801997
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FtsZ-Independent Mechanism of Division Inhibition by the Small Molecule PC190723 in Escherichia coli.
    Khare S; Hsin J; Sorto NA; Nepomuceno GM; Shaw JT; Shi H; Huang KC
    Adv Biosyst; 2019 Nov; 3(11):e1900021. PubMed ID: 32648693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics.
    Tan CM; Therien AG; Lu J; Lee SH; Caron A; Gill CJ; Lebeau-Jacob C; Benton-Perdomo L; Monteiro JM; Pereira PM; Elsen NL; Wu J; Deschamps K; Petcu M; Wong S; Daigneault E; Kramer S; Liang L; Maxwell E; Claveau D; Vaillancourt J; Skorey K; Tam J; Wang H; Meredith TC; Sillaots S; Wang-Jarantow L; Ramtohul Y; Langlois E; Landry F; Reid JC; Parthasarathy G; Sharma S; Baryshnikova A; Lumb KJ; Pinho MG; Soisson SM; Roemer T
    Sci Transl Med; 2012 Mar; 4(126):126ra35. PubMed ID: 22440737
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A benzamide-dependent ftsZ mutant reveals residues crucial for Z-ring assembly.
    Adams DW; Wu LJ; Errington J
    Mol Microbiol; 2016 Mar; 99(6):1028-42. PubMed ID: 26601800
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The antibacterial cell division inhibitor PC190723 is an FtsZ polymer-stabilizing agent that induces filament assembly and condensation.
    Andreu JM; Schaffner-Barbero C; Huecas S; Alonso D; Lopez-Rodriguez ML; Ruiz-Avila LB; Núñez-Ramírez R; Llorca O; Martín-Galiano AJ
    J Biol Chem; 2010 May; 285(19):14239-46. PubMed ID: 20212044
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RfiA, a novel PAP2 domain-containing polytopic membrane protein that confers resistance to the FtsZ inhibitor PC190723.
    Chen X; Zhang B; Xiao J; Ju F; Li S; Ren C; An L; Chen T; Liu G; Facey P; Mullins JG; Dyson P
    Future Microbiol; 2015; 10(3):325-35. PubMed ID: 25812456
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enterococcal and streptococcal resistance to PC190723 and related compounds: molecular insights from a FtsZ mutational analysis.
    Kaul M; Zhang Y; Parhi AK; Lavoie EJ; Tuske S; Arnold E; Kerrigan JE; Pilch DS
    Biochimie; 2013 Oct; 95(10):1880-7. PubMed ID: 23806423
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exploration of the inhibitory mechanism of PC190723 on FtsZ protein by molecular dynamics simulation.
    Ma Y; Zhang S; Zhou L; Zhang L; Zhang P; Ma S
    J Mol Graph Model; 2022 Jul; 114():108189. PubMed ID: 35453046
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Practical synthesis of PC190723, an inhibitor of the bacterial cell division protein FtsZ.
    Sorto NA; Olmstead MM; Shaw JT
    J Org Chem; 2010 Nov; 75(22):7946-9. PubMed ID: 21033691
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An FtsZ-targeting prodrug with oral antistaphylococcal efficacy in vivo.
    Kaul M; Mark L; Zhang Y; Parhi AK; Lavoie EJ; Pilch DS
    Antimicrob Agents Chemother; 2013 Dec; 57(12):5860-9. PubMed ID: 24041882
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of small molecule inhibitors of the bacterial cell division protein FtsZ and identification of a reliable cross-species inhibitor.
    Anderson DE; Kim MB; Moore JT; O'Brien TE; Sorto NA; Grove CI; Lackner LL; Ames JB; Shaw JT
    ACS Chem Biol; 2012 Nov; 7(11):1918-28. PubMed ID: 22958099
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
    Huecas S; Canosa-Valls AJ; Araújo-Bazán L; Ruiz FM; Laurents DV; Fernández-Tornero C; Andreu JM
    FEBS J; 2020 Sep; 287(18):4048-4067. PubMed ID: 31997533
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural reorganization of the bacterial cell-division protein FtsZ from Staphylococcus aureus.
    Matsui T; Yamane J; Mogi N; Yamaguchi H; Takemoto H; Yao M; Tanaka I
    Acta Crystallogr D Biol Crystallogr; 2012 Sep; 68(Pt 9):1175-88. PubMed ID: 22948918
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insights into nucleotide recognition by cell division protein FtsZ from a mant-GTP competition assay and molecular dynamics.
    Schaffner-Barbero C; Gil-Redondo R; Ruiz-Avila LB; Huecas S; Läppchen T; den Blaauwen T; Diaz JF; Morreale A; Andreu JM
    Biochemistry; 2010 Dec; 49(49):10458-72. PubMed ID: 21058659
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural insights of Staphylococcus aureus FtsZ inhibitors through molecular docking, 3D-QSAR and molecular dynamics simulations.
    Ballu S; Itteboina R; Sivan SK; Manga V
    J Recept Signal Transduct Res; 2018 Feb; 38(1):61-70. PubMed ID: 29369011
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.
    Huecas S; Araújo-Bazán L; Ruiz FM; Ruiz-Ávila LB; Martínez RF; Escobar-Peña A; Artola M; Vázquez-Villa H; Martín-Fontecha M; Fernández-Tornero C; López-Rodríguez ML; Andreu JM
    J Med Chem; 2021 May; 64(9):5730-5745. PubMed ID: 33908781
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ.
    Ruiz-Avila LB; Huecas S; Artola M; Vergoñós A; Ramírez-Aportela E; Cercenado E; Barasoain I; Vázquez-Villa H; Martín-Fontecha M; Chacón P; López-Rodríguez ML; Andreu JM
    ACS Chem Biol; 2013 Sep; 8(9):2072-83. PubMed ID: 23855511
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of RND-type efflux pumps confers the FtsZ-directed prodrug TXY436 with activity against Gram-negative bacteria.
    Kaul M; Zhang Y; Parhi AK; Lavoie EJ; Pilch DS
    Biochem Pharmacol; 2014 Jun; 89(3):321-8. PubMed ID: 24637241
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.