These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 25817387)

  • 21. Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase.
    Hewitt SN; Dranow DM; Horst BG; Abendroth JA; Forte B; Hallyburton I; Jansen C; Baragaña B; Choi R; Rivas KL; Hulverson MA; Dumais M; Edwards TE; Lorimer DD; Fairlamb AH; Gray DW; Read KD; Lehane AM; Kirk K; Myler PJ; Wernimont A; Walpole C; Stacy R; Barrett LK; Gilbert IH; Van Voorhis WC
    ACS Infect Dis; 2017 Jan; 3(1):34-44. PubMed ID: 27798837
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study.
    Nyamai DW; Tastan Bishop Ö
    Malar J; 2019 Feb; 18(1):34. PubMed ID: 30728021
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.
    Kim Y; Sundrud MS; Zhou C; Edenius M; Zocco D; Powers K; Zhang M; Mazitschek R; Rao A; Yeo CY; Noss EH; Brenner MB; Whitman M; Keller TL
    Proc Natl Acad Sci U S A; 2020 Apr; 117(16):8900-8911. PubMed ID: 32253314
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.
    Yogavel M; Bougdour A; Mishra S; Malhotra N; Chhibber-Goel J; Bellini V; Harlos K; Laleu B; Hakimi MA; Sharma A
    PLoS Pathog; 2023 Feb; 19(2):e1011124. PubMed ID: 36854028
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Characterization of Plasmodium liver stage inhibition by halofuginone.
    Derbyshire ER; Mazitschek R; Clardy J
    ChemMedChem; 2012 May; 7(5):844-9. PubMed ID: 22438279
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Dimerization of Arginyl-tRNA Synthetase by Free Heme Drives Its Inactivation in Plasmodium falciparum.
    Jain V; Yogavel M; Sharma A
    Structure; 2016 Sep; 24(9):1476-87. PubMed ID: 27502052
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis and comparison of antimalarial activity of febrifugine derivatives including halofuginone.
    Samant BS; Sukhthankar MG
    Med Chem; 2009 May; 5(3):293-300. PubMed ID: 19442220
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Prospects of halofuginone as an antiprotozoal drug scaffold.
    Gill J; Sharma A
    Drug Discov Today; 2022 Sep; 27(9):2586-2592. PubMed ID: 35636724
    [TBL] [Abstract][Full Text] [Related]  

  • 29. New type of febrifugine analogues, bearing a quinolizidine moiety, show potent antimalarial activity against Plasmodium malaria parasite.
    Takaya Y; Tasaka H; Chiba T; Uwai K; Tanitsu M; Kim HS; Wataya Y; Miura M; Takeshita M; Oshima Y
    J Med Chem; 1999 Aug; 42(16):3163-6. PubMed ID: 10447961
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin.
    Khan S; Sharma A; Belrhali H; Yogavel M; Sharma A
    J Struct Funct Genomics; 2014 Jun; 15(2):63-71. PubMed ID: 24935905
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region.
    Gambini L; Rizzi L; Pedretti A; Taglialatela-Scafati O; Carucci M; Pancotti A; Galli C; Read M; Giurisato E; Romeo S; Russo I
    PLoS One; 2015; 10(11):e0142509. PubMed ID: 26566224
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Drug targeting of one or more aminoacyl-tRNA synthetase in the malaria parasite Plasmodium falciparum.
    Manickam Y; Chaturvedi R; Babbar P; Malhotra N; Jain V; Sharma A
    Drug Discov Today; 2018 Jun; 23(6):1233-1240. PubMed ID: 29408369
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Anti-Phytophthora Activity of Halofuginone and the Corresponding Mode of Action.
    Zhang S; Cai J; Xie Y; Zhang X; Yang X; Lin S; Xiang W; Zhang J
    J Agric Food Chem; 2022 Oct; 70(39):12364-12371. PubMed ID: 36126316
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and evaluation of 4-quinazolinone compounds as potential antimalarial agents.
    Zhu S; Wang J; Chandrashekar G; Smith E; Liu X; Zhang Y
    Eur J Med Chem; 2010 Sep; 45(9):3864-9. PubMed ID: 20538379
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as
    Okaniwa M; Shibata A; Ochida A; Akao Y; White KL; Shackleford DM; Duffy S; Lucantoni L; Dey S; Striepen J; Yeo T; Mok S; Aguiar ACC; Sturm A; Crespo B; Sanz LM; Churchyard A; Baum J; Pereira DB; Guido RVC; Dechering KJ; Wittlin S; Uhlemann AC; Fidock DA; Niles JC; Avery VM; Charman SA; Laleu B
    ACS Infect Dis; 2021 Jun; 7(6):1680-1689. PubMed ID: 33929818
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor.
    Fang P; Han H; Wang J; Chen K; Chen X; Guo M
    Chem Biol; 2015 Jun; 22(6):734-44. PubMed ID: 26074468
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
    AhYoung AP; Koehl A; Cascio D; Egea PF
    Protein Sci; 2015 Sep; 24(9):1508-20. PubMed ID: 26130467
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Metabolites of febrifugine and its synthetic analogue by mouse liver S9 and their antimalarial activity against Plasmodium malaria parasite.
    Hirai S; Kikuchi H; Kim HS; Begum K; Wataya Y; Tasaka H; Miyazawa Y; Yamamoto K; Oshima Y
    J Med Chem; 2003 Sep; 46(20):4351-9. PubMed ID: 13678413
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials.
    Laleu B; Akao Y; Ochida A; Duffy S; Lucantoni L; Shackleford DM; Chen G; Katneni K; Chiu FCK; White KL; Chen X; Sturm A; Dechering KJ; Crespo B; Sanz LM; Wang B; Wittlin S; Charman SA; Avery VM; Cho N; Kamaura M
    J Med Chem; 2021 Sep; 64(17):12582-12602. PubMed ID: 34437804
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Exploration of a new type of antimalarial compounds based on febrifugine.
    Kikuchi H; Yamamoto K; Horoiwa S; Hirai S; Kasahara R; Hariguchi N; Matsumoto M; Oshima Y
    J Med Chem; 2006 Jul; 49(15):4698-706. PubMed ID: 16854076
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.