BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 25817588)

  • 1. Novel hybrid nocodazole analogues as tubulin polymerization inhibitors and their antiproliferative activity.
    Kale SS; Jedhe GS; Meshram SN; Santra MK; Hamel E; Sanjayan GJ
    Bioorg Med Chem Lett; 2015 May; 25(9):1982-5. PubMed ID: 25817588
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
    Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of 4-morpholino-6-(1,2,3,6-tetrahydropyridin-4-yl)-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazin-2-amine analogues as tubulin polymerization inhibitors.
    Narva S; Chitti S; Amaroju S; Bhattacharjee D; Rao BB; Jain N; Alvala M; Sekhar KVGC
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3794-3801. PubMed ID: 28684120
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
    Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, Synthesis and Evaluation of 2,4-Diaminoquinazoline Derivatives as Potential Tubulin Polymerization Inhibitors.
    Herrera-Vázquez FS; Matadamas-Martínez F; Aguayo-Ortiz R; Dominguez L; Ramírez-Apan T; Yépez-Mulia L; Hernández-Luis F
    ChemMedChem; 2020 Oct; 15(19):1802-1812. PubMed ID: 32686342
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological evaluation of 1-substituted -2-aryl imidazoles targeting tubulin polymerization as potential anticancer agents.
    Li L; Quan D; Chen J; Ding J; Zhao J; Lv L; Chen J
    Eur J Med Chem; 2019 Dec; 184():111732. PubMed ID: 31610372
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of arylcinnamide linked combretastatin-A4 hybrids as tubulin polymerization inhibitors and apoptosis inducing agents.
    Kamal A; Bajee S; Lakshma Nayak V; Venkata Subba Rao A; Nagaraju B; Ratna Reddy C; Jeevak Sopanrao K; Alarifi A
    Bioorg Med Chem Lett; 2016 Jun; 26(12):2957-2964. PubMed ID: 27161282
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor.
    Ameri A; Khodarahmi G; Forootanfar H; Hassanzadeh F; Hakimelahi GH
    Chem Biodivers; 2018 Mar; 15(3):e1700518. PubMed ID: 29292595
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
    Romagnoli R; Oliva P; Salvador MK; Manfredini S; Padroni C; Brancale A; Ferla S; Hamel E; Ronca R; Maccarinelli F; Rruga F; Mariotto E; Viola G; Bortolozzi R
    Eur J Med Chem; 2021 Mar; 214():113229. PubMed ID: 33550186
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
    Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues.
    Mustafa M; Abdelhamid D; Abdelhafez EMN; Ibrahim MAA; Gamal-Eldeen AM; Aly OM
    Eur J Med Chem; 2017 Dec; 141():293-305. PubMed ID: 29031074
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors.
    Kamal A; Ashraf M; Basha ST; Ali Hussaini SM; Singh S; Vishnuvardhan MV; Kiran B; Sridhar B
    Org Biomol Chem; 2016 Jan; 14(4):1382-94. PubMed ID: 26676480
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation.
    Naret T; Bignon J; Bernadat G; Benchekroun M; Levaique H; Lenoir C; Dubois J; Pruvost A; Saller F; Borgel D; Manoury B; Leblais V; Darrigrand R; Apcher S; Brion JD; Schmitt E; Leroux FR; Alami M; Hamze A
    Eur J Med Chem; 2018 Jan; 143():473-490. PubMed ID: 29202409
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G; Li C; He L; Lei K; Wang F; Pu Y; Yang Z; Cao D; Ma L; Chen J; Sang Y; Liang X; Xiang M; Peng A; Wei Y; Chen L
    Bioorg Med Chem; 2014 Apr; 22(7):2060-79. PubMed ID: 24629450
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of N-substituted 3-oxo-1,2,3,4-tetrahydro-quinoxaline-6-carboxylic acid derivatives as tubulin polymerization inhibitors.
    Qi J; Dong H; Huang J; Zhang S; Niu L; Zhang Y; Wang J
    Eur J Med Chem; 2018 Jan; 143():8-20. PubMed ID: 29172084
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and bio-evaluation of novel 2-aryl-4-(3,4,5-trimethoxy-benzoyl)-5-substituted-1,2,3-triazoles as the tubulin polymerization inhibitors.
    Huang L; Liu M; Man S; Ma D; Feng D; Sun Z; Guan Q; Zuo D; Wu Y; Zhang W; Bao K
    Eur J Med Chem; 2020 Jan; 186():111846. PubMed ID: 31740055
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, molecular modeling, and biological evaluation of pyrazole-naphthalene derivatives as potential anticancer agents on MCF-7 breast cancer cells by inhibiting tubulin polymerization.
    Wang G; Liu W; Peng Z; Huang Y; Gong Z; Li Y
    Bioorg Chem; 2020 Oct; 103():104141. PubMed ID: 32750611
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F; He CP; Diao PC; Hong KH; Rao JJ; Zhao PL
    Bioorg Med Chem Lett; 2019 Jan; 29(1):22-27. PubMed ID: 30448234
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers.
    Subba Rao AV; Swapna K; Shaik SP; Lakshma Nayak V; Srinivasa Reddy T; Sunkari S; Shaik TB; Bagul C; Kamal A
    Bioorg Med Chem; 2017 Feb; 25(3):977-999. PubMed ID: 28034647
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Correlation of hydrogen-bonding propensity and anticancer profile of tetrazole-tethered combretastatin analogues.
    Jedhe GS; Paul D; Gonnade RG; Santra MK; Hamel E; Nguyen TL; Sanjayan GJ
    Bioorg Med Chem Lett; 2013 Aug; 23(16):4680-4. PubMed ID: 23809851
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.