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2. ALS-Linked P56S-VAPB Mutation Impairs the Formation of Multinuclear Myotube in C2C12 Cells. Tokutake Y; Yamada K; Ohata M; Obayashi Y; Tsuchiya M; Yonekura S Int J Mol Sci; 2015 Aug; 16(8):18628-41. PubMed ID: 26266407 [TBL] [Abstract][Full Text] [Related]
3. Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons. Aliaga L; Lai C; Yu J; Chub N; Shim H; Sun L; Xie C; Yang WJ; Lin X; O'Donovan MJ; Cai H Hum Mol Genet; 2013 Nov; 22(21):4293-305. PubMed ID: 23771029 [TBL] [Abstract][Full Text] [Related]
4. Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8). Kanekura K; Nishimoto I; Aiso S; Matsuoka M J Biol Chem; 2006 Oct; 281(40):30223-33. PubMed ID: 16891305 [TBL] [Abstract][Full Text] [Related]
5. Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response. Larroquette F; Seto L; Gaub PL; Kamal B; Wallis D; Larivière R; Vallée J; Robitaille R; Tsuda H Hum Mol Genet; 2015 Nov; 24(22):6515-29. PubMed ID: 26362257 [TBL] [Abstract][Full Text] [Related]
6. ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB. Suzuki H; Kanekura K; Levine TP; Kohno K; Olkkonen VM; Aiso S; Matsuoka M J Neurochem; 2009 Feb; 108(4):973-985. PubMed ID: 19183264 [TBL] [Abstract][Full Text] [Related]
7. Restructured endoplasmic reticulum generated by mutant amyotrophic lateral sclerosis-linked VAPB is cleared by the proteasome. Papiani G; Ruggiano A; Fossati M; Raimondi A; Bertoni G; Francolini M; Benfante R; Navone F; Borgese N J Cell Sci; 2012 Aug; 125(Pt 15):3601-11. PubMed ID: 22611258 [TBL] [Abstract][Full Text] [Related]
8. Atypical familial amyotrophic lateral sclerosis with initial symptoms of pain or tremor in a Chinese family harboring VAPB-P56S mutation. Di L; Chen H; Da Y; Wang S; Shen XM J Neurol; 2016 Feb; 263(2):263-268. PubMed ID: 26566915 [TBL] [Abstract][Full Text] [Related]
10. Amyotrophic lateral sclerosis-linked mutant VAPB inclusions do not interfere with protein degradation pathways or intracellular transport in a cultured cell model. Genevini P; Papiani G; Ruggiano A; Cantoni L; Navone F; Borgese N PLoS One; 2014; 9(11):e113416. PubMed ID: 25409455 [TBL] [Abstract][Full Text] [Related]
11. Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice. Qiu L; Qiao T; Beers M; Tan W; Wang H; Yang B; Xu Z Mol Neurodegener; 2013 Jan; 8():1. PubMed ID: 23281774 [TBL] [Abstract][Full Text] [Related]
12. Investigating the contribution of VAPB/ALS8 loss of function in amyotrophic lateral sclerosis. Kabashi E; El Oussini H; Bercier V; Gros-Louis F; Valdmanis PN; McDearmid J; Mejier IA; Dion PA; Dupre N; Hollinger D; Sinniger J; Dirrig-Grosch S; Camu W; Meininger V; Loeffler JP; René F; Drapeau P; Rouleau GA; Dupuis L Hum Mol Genet; 2013 Jun; 22(12):2350-60. PubMed ID: 23446633 [TBL] [Abstract][Full Text] [Related]
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15. Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation. Tripathi P; Guo H; Dreser A; Yamoah A; Sechi A; Jesse CM; Katona I; Doukas P; Nikolin S; Ernst S; Aronica E; Glaß H; Hermann A; Steinbusch H; Feller AC; Bergmann M; Jaarsma D; Weis J; Goswami A Cell Death Dis; 2021 May; 12(5):466. PubMed ID: 33972508 [TBL] [Abstract][Full Text] [Related]
16. Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis. Landry C; Costanzo J; Mitne-Neto M; Zatz M; Schaffer A; Hatzoglou M; Muotri A; Miranda HC bioRxiv; 2024 May; ():. PubMed ID: 38798645 [TBL] [Abstract][Full Text] [Related]
17. New VAPB deletion variant and exclusion of VAPB mutations in familial ALS. Landers JE; Leclerc AL; Shi L; Virkud A; Cho T; Maxwell MM; Henry AF; Polak M; Glass JD; Kwiatkowski TJ; Al-Chalabi A; Shaw CE; Leigh PN; Rodriguez-Leyza I; McKenna-Yasek D; Sapp PC; Brown RH Neurology; 2008 Apr; 70(14):1179-85. PubMed ID: 18322265 [TBL] [Abstract][Full Text] [Related]
18. Amyotrophic lateral sclerosis (ALS)-associated VAPB-P56S inclusions represent an ER quality control compartment. Kuijpers M; van Dis V; Haasdijk ED; Harterink M; Vocking K; Post JA; Scheper W; Hoogenraad CC; Jaarsma D Acta Neuropathol Commun; 2013 Jun; 1():24. PubMed ID: 24252306 [TBL] [Abstract][Full Text] [Related]
19. Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates. Teuling E; Ahmed S; Haasdijk E; Demmers J; Steinmetz MO; Akhmanova A; Jaarsma D; Hoogenraad CC J Neurosci; 2007 Sep; 27(36):9801-15. PubMed ID: 17804640 [TBL] [Abstract][Full Text] [Related]
20. Protein aggregation due to nsSNP resulting in P56S VABP protein is associated with amyotrophic lateral sclerosis. Vinay Kumar C; Kumar KM; Swetha R; Ramaiah S; Anbarasu A J Theor Biol; 2014 Aug; 354():72-80. PubMed ID: 24681403 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]