These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

366 related articles for article (PubMed ID: 25825523)

  • 1. Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling.
    Tsukiyama T; Fukui A; Terai S; Fujioka Y; Shinada K; Takahashi H; Yamaguchi TP; Ohba Y; Hatakeyama S
    Mol Cell Biol; 2015 Jun; 35(11):2007-23. PubMed ID: 25825523
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma.
    Jiang X; Hao HX; Growney JD; Woolfenden S; Bottiglio C; Ng N; Lu B; Hsieh MH; Bagdasarian L; Meyer R; Smith TR; Avello M; Charlat O; Xie Y; Porter JA; Pan S; Liu J; McLaughlin ME; Cong F
    Proc Natl Acad Sci U S A; 2013 Jul; 110(31):12649-54. PubMed ID: 23847203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.
    Loregger A; Grandl M; Mejías-Luque R; Allgäuer M; Degenhart K; Haselmann V; Oikonomou C; Hatzis P; Janssen KP; Nitsche U; Gradl D; van den Broek O; Destree O; Ulm K; Neumaier M; Kalali B; Jung A; Varela I; Schmid RM; Rad R; Busch DH; Gerhard M
    Sci Signal; 2015 Sep; 8(393):ra90. PubMed ID: 26350900
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RNF43 R117fs mutant positively regulates Wnt/β-catenin signaling by failing to internalize FZD expressed on the cell surface.
    Cho AR; Sul HJ; Kim YJ; Kim B; Zang DY
    Sci Rep; 2022 Apr; 12(1):7013. PubMed ID: 35487932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rnf43.
    Serra S; Chetty R
    J Clin Pathol; 2018 Jan; 71(1):1-6. PubMed ID: 29018044
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.
    Jiang X; Charlat O; Zamponi R; Yang Y; Cong F
    Mol Cell; 2015 May; 58(3):522-33. PubMed ID: 25891077
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells.
    Radaszkiewicz T; Bryja V
    Cell Commun Signal; 2020 Jun; 18(1):91. PubMed ID: 32527265
    [TBL] [Abstract][Full Text] [Related]  

  • 8. USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.
    Madan B; Walker MP; Young R; Quick L; Orgel KA; Ryan M; Gupta P; Henrich IC; Ferrer M; Marine S; Roberts BS; Arthur WT; Berndt JD; Oliveira AM; Moon RT; Virshup DM; Chou MM; Major MB
    Proc Natl Acad Sci U S A; 2016 May; 113(21):E2945-54. PubMed ID: 27162353
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition.
    Yu J; Yusoff PAM; Woutersen DTJ; Goh P; Harmston N; Smits R; Epstein DM; Virshup DM; Madan B
    Cancer Res; 2020 Dec; 80(24):5619-5632. PubMed ID: 33067269
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene.
    Takahashi N; Yamaguchi K; Ikenoue T; Fujii T; Furukawa Y
    PLoS One; 2014; 9(1):e86582. PubMed ID: 24466159
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells.
    Lyons JP; Mueller UW; Ji H; Everett C; Fang X; Hsieh JC; Barth AM; McCrea PD
    Exp Cell Res; 2004 Aug; 298(2):369-87. PubMed ID: 15265686
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.
    Li S; Lavrijsen M; Bakker A; Magierowski M; Magierowska K; Liu P; Wang W; Peppelenbosch MP; Smits R
    Oncogene; 2020 Apr; 39(17):3458-3472. PubMed ID: 32103169
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways.
    Qi J; Lee HJ; Saquet A; Cheng XN; Shao M; Zheng JJ; Shi DL
    J Biol Chem; 2017 Apr; 292(14):5898-5908. PubMed ID: 28223363
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors.
    Schweizer L; Varmus H
    BMC Cell Biol; 2003 May; 4():4. PubMed ID: 12729465
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
    Koo BK; Spit M; Jordens I; Low TY; Stange DE; van de Wetering M; van Es JH; Mohammed S; Heck AJ; Maurice MM; Clevers H
    Nature; 2012 Aug; 488(7413):665-9. PubMed ID: 22895187
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ring finger protein 43 associates with gastric cancer progression and attenuates the stemness of gastric cancer stem-like cells via the Wnt-β/catenin signaling pathway.
    Gao Y; Cai A; Xi H; Li J; Xu W; Zhang Y; Zhang K; Cui J; Wu X; Wei B; Chen L
    Stem Cell Res Ther; 2017 Apr; 8(1):98. PubMed ID: 28446252
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ubiquitin ligase RNF43 downregulation increases membrane expression of frizzled receptor in pancreatic ductal adenocarcinoma.
    Wang D; Tan J; Xu Y; Han M; Tu Y; Zhu Z; Dou C; Xin J; Tan X; Zeng JP; Zhao G; Liu Z
    Tumour Biol; 2016 Jan; 37(1):627-31. PubMed ID: 26240024
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Daple-Akt feed-forward loop enhances noncanonical Wnt signals by compartmentalizing β-catenin.
    Aznar N; Sun N; Dunkel Y; Ear J; Buschman MD; Ghosh P
    Mol Biol Cell; 2017 Dec; 28(25):3709-3723. PubMed ID: 29021338
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling.
    Umbhauer M; Djiane A; Goisset C; Penzo-Méndez A; Riou JF; Boucaut JC; Shi DL
    EMBO J; 2000 Sep; 19(18):4944-54. PubMed ID: 10990458
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.
    Cong F; Schweizer L; Varmus H
    Development; 2004 Oct; 131(20):5103-15. PubMed ID: 15459103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.