BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 25832557)

  • 21. Nanoencapsulation of MDM2 Inhibitor RG7388 and Class-I HDAC Inhibitor Entinostat Enhances their Therapeutic Potential Through Synergistic Antitumor Effects and Reduction of Systemic Toxicity.
    Abed A; Greene MK; Alsa'd AA; Lees A; Hindley A; Longley DB; McDade SS; Scott CJ
    Mol Pharm; 2024 Mar; 21(3):1246-1255. PubMed ID: 38334409
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Antitumour activity of the glycoengineered type II anti-CD20 antibody obinutuzumab (GA101) in combination with the MDM2-selective antagonist idasanutlin (RG7388).
    Herting F; Herter S; Friess T; Muth G; Bacac M; Sulcova J; Umana P; Dangl M; Klein C
    Eur J Haematol; 2016 Nov; 97(5):461-470. PubMed ID: 26993060
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Hyperfractionated radiation in children with rhabdomyosarcoma--results of an Intergroup Rhabdomyosarcoma Pilot Study.
    Donaldson SS; Asmar L; Breneman J; Fryer C; Glicksman AS; Laurie F; Wharam M; Gehan EA
    Int J Radiat Oncol Biol Phys; 1995 Jul; 32(4):903-11. PubMed ID: 7607964
    [TBL] [Abstract][Full Text] [Related]  

  • 24. MDM2 Antagonists Counteract Drug-Induced DNA Damage.
    Vilgelm AE; Cobb P; Malikayil K; Flaherty D; Andrew Johnson C; Raman D; Saleh N; Higgins B; Vara BA; Johnston JN; Johnson DB; Kelley MC; Chen SC; Ayers GD; Richmond A
    EBioMedicine; 2017 Oct; 24():43-55. PubMed ID: 29030058
    [TBL] [Abstract][Full Text] [Related]  

  • 25. BI-907828, a novel potent MDM2 inhibitor, inhibits glioblastoma brain tumor stem cells in vitro and prolongs survival in orthotopic xenograft mouse models.
    Hao X; Bahia RK; Cseh O; Bozek DA; Blake S; Rinnenthal J; Weyer-Czernilofsky U; Rudolph D; Artee Luchman H
    Neuro Oncol; 2023 May; 25(5):913-926. PubMed ID: 36521007
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma.
    Wu CE; Esfandiari A; Ho YH; Wang N; Mahdi AK; Aptullahoglu E; Lovat P; Lunec J
    Br J Cancer; 2018 Feb; 118(4):495-508. PubMed ID: 29235570
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synergistic activity and heterogeneous acquired resistance of combined MDM2 and MEK inhibition in KRAS mutant cancers.
    Hata AN; Rowley S; Archibald HL; Gomez-Caraballo M; Siddiqui FM; Ji F; Jung J; Light M; Lee JS; Debussche L; Sidhu S; Sadreyev RI; Watters J; Engelman JA
    Oncogene; 2017 Nov; 36(47):6581-6591. PubMed ID: 28783173
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Inhibition of MEK confers hypersensitivity to X-radiation in the context of BRAF mutation in a model of childhood astrocytoma.
    Studebaker A; Bondra K; Seum S; Shen C; Phelps DA; Chronowski C; Leasure J; Smith PD; Kurmasheva RT; Mo X; Fouladi M; Houghton PJ
    Pediatr Blood Cancer; 2015 Oct; 62(10):1768-74. PubMed ID: 25981859
    [TBL] [Abstract][Full Text] [Related]  

  • 29. MDM2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Ablation and Radiotherapy in a p53-Dependent Manner.
    Feng FY; Zhang Y; Kothari V; Evans JR; Jackson WC; Chen W; Johnson SB; Luczak C; Wang S; Hamstra DA
    Neoplasia; 2016 Apr; 18(4):213-22. PubMed ID: 27108384
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Reactivation of p53 via MDM2 inhibition.
    Kim ES; Shohet JM
    Cell Death Dis; 2015 Oct; 6(10):e1936. PubMed ID: 26492369
    [No Abstract]   [Full Text] [Related]  

  • 31. Characterisation of the p53 pathway in cell lines established from TH-MYCN transgenic mouse tumours.
    Chen L; Esfandiari A; Reaves W; Vu A; Hogarty MD; Lunec J; Tweddle DA
    Int J Oncol; 2018 Mar; 52(3):967-977. PubMed ID: 29393340
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Highly Potent Clickable Probe for Cellular Imaging of MDM2 and Assessing Dynamic Responses to MDM2-p53 Inhibition.
    Lebraud H; Noble RA; Phillips N; Heam K; Castro J; Zhao Y; Newell DR; Lunec J; Wedge SR; Heightman TD
    Bioconjug Chem; 2018 Jun; 29(6):2100-2106. PubMed ID: 29851469
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Resveratrol enhances radiation sensitivity in prostate cancer by inhibiting cell proliferation and promoting cell senescence and apoptosis.
    Fang Y; DeMarco VG; Nicholl MB
    Cancer Sci; 2012 Jun; 103(6):1090-8. PubMed ID: 22417066
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Radiosensitization of Adenoid Cystic Carcinoma with MDM2 Inhibition.
    Prabakaran PJ; Javaid AM; Swick AD; Werner LR; Nickel KP; Sampene E; Hu R; Ong IM; Bruce JY; Hartig GK; Wieland AM; Canon J; Harari PM; Kimple RJ
    Clin Cancer Res; 2017 Oct; 23(20):6044-6053. PubMed ID: 28659312
    [No Abstract]   [Full Text] [Related]  

  • 35. Splicing Modulation Results in Aberrant Isoforms and Protein Products of p53 Pathway Genes and the Sensitization of B Cells to Non-Genotoxic MDM2 Inhibition.
    Aptullahoglu E; Ciardullo C; Wallis JP; Marr H; Marshall S; Bown N; Willmore E; Lunec J
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768733
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The effects of combining ionizing radiation and adenoviral p53 therapy in nasopharyngeal carcinoma.
    Li JH; Lax SA; Kim J; Klamut H; Liu FF
    Int J Radiat Oncol Biol Phys; 1999 Feb; 43(3):607-16. PubMed ID: 10078646
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Phase I study of daily and weekly regimens of the orally administered MDM2 antagonist idasanutlin in patients with advanced tumors.
    Italiano A; Miller WH; Blay JY; Gietema JA; Bang YJ; Mileshkin LR; Hirte HW; Higgins B; Blotner S; Nichols GL; Chen LC; Petry C; Yang QJ; Schmitt C; Jamois C; Siu LL
    Invest New Drugs; 2021 Dec; 39(6):1587-1597. PubMed ID: 34180037
    [TBL] [Abstract][Full Text] [Related]  

  • 38. In vivo efficacy of the histone deacetylase inhibitor suberoylanilide hydroxamic acid in combination with radiotherapy in a malignant rhabdoid tumor mouse model.
    Thiemann M; Oertel S; Ehemann V; Weichert W; Stenzinger A; Bischof M; Weber KJ; Perez RL; Haberkorn U; Kulozik AE; Debus J; Huber PE; Battmann C
    Radiat Oncol; 2012 Mar; 7():52. PubMed ID: 22458853
    [TBL] [Abstract][Full Text] [Related]  

  • 39. MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.
    Tisato V; Voltan R; Gonelli A; Secchiero P; Zauli G
    J Hematol Oncol; 2017 Jul; 10(1):133. PubMed ID: 28673313
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Anti-tumor activity of the MDM2-TP53 inhibitor BI-907828 in dedifferentiated liposarcoma patient-derived xenograft models harboring MDM2 amplification.
    Cornillie J; Wozniak A; Li H; Gebreyohannes YK; Wellens J; Hompes D; Debiec-Rychter M; Sciot R; Schöffski P
    Clin Transl Oncol; 2020 Apr; 22(4):546-554. PubMed ID: 31201607
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.