BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

584 related articles for article (PubMed ID: 25835148)

  • 1. Expression of hepatic cytochrome P450s and UDP-glucuronosyltransferases in PXR and CAR double humanized mice treated with rifampicin.
    Lee SY; Lee JY; Kim YM; Kim SK; Oh SJ
    Toxicol Lett; 2015 Jun; 235(2):107-15. PubMed ID: 25835148
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
    Fisher CD; Jackson JP; Lickteig AJ; Augustine LM; Cherrington NJ
    Arch Toxicol; 2008 Dec; 82(12):959-64. PubMed ID: 18488193
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice.
    Scheer N; Ross J; Kapelyukh Y; Rode A; Wolf CR
    Drug Metab Dispos; 2010 Jul; 38(7):1046-53. PubMed ID: 20354104
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
    Cheng X; Klaassen CD
    Toxicol Sci; 2008 Nov; 106(1):29-36. PubMed ID: 18648086
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vivo induction of CYP in mice by carbamazepine is independent on PXR.
    Liu A; Wang C; Hehir M; Zhou T; Yang J
    Pharmacol Rep; 2015 Apr; 67(2):299-304. PubMed ID: 25712654
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
    Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
    Park YJ; Lee EK; Lee YK; Park DJ; Jang HC; Moore DD
    Toxicol Appl Pharmacol; 2012 Sep; 263(2):131-7. PubMed ID: 22503787
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P; Zhang J; Dowhan DH; Han Y; Moore DD
    Pharmacogenomics J; 2002; 2(2):117-26. PubMed ID: 12049174
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
    Roques BB; Leghait J; Lacroix MZ; Lasserre F; Pineau T; ViguiƩ C; Martin PG
    Biochem Pharmacol; 2013 Oct; 86(7):997-1039. PubMed ID: 23962444
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Octachlorostyrene induces cytochrome P450, UDP-glucuronosyltransferase, and sulfotransferase via the aryl hydrocarbon receptor and constitutive androstane receptor.
    Yanagiba Y; Ito Y; Kamijima M; Gonzalez FJ; Nakajima T
    Toxicol Sci; 2009 Sep; 111(1):19-26. PubMed ID: 19525444
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.
    Ross J; Plummer SM; Rode A; Scheer N; Bower CC; Vogel O; Henderson CJ; Wolf CR; Elcombe CR
    Toxicol Sci; 2010 Aug; 116(2):452-66. PubMed ID: 20403969
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Decreased PXR and CAR inhibit transporter and CYP mRNA Levels in the liver and intestine of mice with collagen-induced arthritis.
    Kawase A; Yoshida I; Tsunokuni Y; Iwaki M
    Xenobiotica; 2007 Apr; 37(4):366-74. PubMed ID: 17455111
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators.
    Pacyniak EK; Cheng X; Cunningham ML; Crofton K; Klaassen CD; Guo GL
    Toxicol Sci; 2007 May; 97(1):94-102. PubMed ID: 17324954
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CAR and PXR expression and inducibility of CYP2B and CYP3A activities in rat and rabbit lungs.
    Chirulli V; Longo V; Marini S; Mazzaccaro A; Fiorio R; Gervasi PG
    Life Sci; 2005 Apr; 76(22):2535-46. PubMed ID: 15769478
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.
    Buckley DB; Klaassen CD
    Drug Metab Dispos; 2009 Apr; 37(4):847-56. PubMed ID: 19144771
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacokinetic-pharmacodynamic modeling of rifampicin-mediated Cyp3a11 induction in steroid and xenobiotic X receptor humanized mice.
    Raybon JJ; Pray D; Morgan DG; Zoeckler M; Zheng M; Sinz M; Kim S
    J Pharmacol Exp Ther; 2011 Apr; 337(1):75-82. PubMed ID: 21205914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
    Kanno Y; Tanuma N; Yazawa S; Zhao S; Inaba M; Nakamura S; Nemoto K; Inouye Y
    Drug Metab Dispos; 2016 Aug; 44(8):1158-63. PubMed ID: 27197997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of lipopolysaccharide on the xenobiotic-induced expression and activity of hepatic cytochrome P450 in mice.
    Moriya N; Kataoka H; Fujino H; Nishikawa J; Kugawa F
    Biol Pharm Bull; 2012; 35(4):473-80. PubMed ID: 22466549
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Indirect activation of pregnane X receptor in the induction of hepatic CYP3A11 by high-dose rifampicin in mice.
    Yamasaki Y; Kobayashi K; Inaba A; Uehara D; Tojima H; Kakizaki S; Chiba K
    Xenobiotica; 2018 Nov; 48(11):1098-1105. PubMed ID: 29095659
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex.
    Ishii Y; Iwanaga M; Nishimura Y; Takeda S; Ikushiro S; Nagata K; Yamazoe Y; Mackenzie PI; Yamada H
    Drug Metab Pharmacokinet; 2007 Oct; 22(5):367-76. PubMed ID: 17965520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.