378 related articles for article (PubMed ID: 25837248)
1. Bordetella pertussis Lipid A Recognition by Toll-like Receptor 4 and MD-2 Is Dependent on Distinct Charged and Uncharged Interfaces.
Maeshima N; Evans-Atkinson T; Hajjar AM; Fernandez RC
J Biol Chem; 2015 May; 290(21):13440-53. PubMed ID: 25837248
[TBL] [Abstract][Full Text] [Related]
2. Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepacia.
Di Lorenzo F; Kubik Ł; Oblak A; Lorè NI; Cigana C; Lanzetta R; Parrilli M; Hamad MA; De Soyza A; Silipo A; Jerala R; Bragonzi A; Valvano MA; Martín-Santamaría S; Molinaro A
J Biol Chem; 2015 Aug; 290(35):21305-19. PubMed ID: 26160169
[TBL] [Abstract][Full Text] [Related]
3. Substitution of the Bordetella pertussis lipid A phosphate groups with glucosamine is required for robust NF-kappaB activation and release of proinflammatory cytokines in cells expressing human but not murine Toll-like receptor 4-MD-2-CD14.
Marr N; Hajjar AM; Shah NR; Novikov A; Yam CS; Caroff M; Fernandez RC
Infect Immun; 2010 May; 78(5):2060-9. PubMed ID: 20176798
[TBL] [Abstract][Full Text] [Related]
4. Recognition of lipid A variants by the TLR4-MD-2 receptor complex.
Maeshima N; Fernandez RC
Front Cell Infect Microbiol; 2013; 3():3. PubMed ID: 23408095
[TBL] [Abstract][Full Text] [Related]
5. Activation of Toll-like receptors by Burkholderia pseudomallei.
West TE; Ernst RK; Jansson-Hutson MJ; Skerrett SJ
BMC Immunol; 2008 Aug; 9():46. PubMed ID: 18691413
[TBL] [Abstract][Full Text] [Related]
6. Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica.
Hajjar AM; Ernst RK; Fortuno ES; Brasfield AS; Yam CS; Newlon LA; Kollmann TR; Miller SI; Wilson CB
PLoS Pathog; 2012; 8(10):e1002963. PubMed ID: 23071439
[TBL] [Abstract][Full Text] [Related]
7. Elucidation of the MD-2/TLR4 interface required for signaling by lipid IVa.
Walsh C; Gangloff M; Monie T; Smyth T; Wei B; McKinley TJ; Maskell D; Gay N; Bryant C
J Immunol; 2008 Jul; 181(2):1245-54. PubMed ID: 18606678
[TBL] [Abstract][Full Text] [Related]
8. MD-2 residues tyrosine 42, arginine 69, aspartic acid 122, and leucine 125 provide species specificity for lipid IVA.
Meng J; Drolet JR; Monks BG; Golenbock DT
J Biol Chem; 2010 Sep; 285(36):27935-43. PubMed ID: 20592019
[TBL] [Abstract][Full Text] [Related]
9. Minor modifications to the phosphate groups and the C3' acyl chain length of lipid A in two Bordetella pertussis strains, BP338 and 18-323, independently affect Toll-like receptor 4 protein activation.
Shah NR; Albitar-Nehme S; Kim E; Marr N; Novikov A; Caroff M; Fernandez RC
J Biol Chem; 2013 Apr; 288(17):11751-60. PubMed ID: 23467413
[TBL] [Abstract][Full Text] [Related]
10. From agonist to antagonist: structure and dynamics of innate immune glycoprotein MD-2 upon recognition of variably acylated bacterial endotoxins.
DeMarco ML; Woods RJ
Mol Immunol; 2011 Oct; 49(1-2):124-33. PubMed ID: 21924775
[TBL] [Abstract][Full Text] [Related]
11. MD-2-mediated ionic interactions between lipid A and TLR4 are essential for receptor activation.
Meng J; Lien E; Golenbock DT
J Biol Chem; 2010 Mar; 285(12):8695-702. PubMed ID: 20018893
[TBL] [Abstract][Full Text] [Related]
12. Structural regions of MD-2 that determine the agonist-antagonist activity of lipid IVa.
Muroi M; Tanamoto K
J Biol Chem; 2006 Mar; 281(9):5484-91. PubMed ID: 16407172
[TBL] [Abstract][Full Text] [Related]
13. Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2.
Ohto U; Fukase K; Miyake K; Shimizu T
Proc Natl Acad Sci U S A; 2012 May; 109(19):7421-6. PubMed ID: 22532668
[TBL] [Abstract][Full Text] [Related]
14. Tailored Modulation of Cellular Pro-inflammatory Responses With Disaccharide Lipid A Mimetics.
Heine H; Adanitsch F; Peternelj TT; Haegman M; Kasper C; Ittig S; Beyaert R; Jerala R; Zamyatina A
Front Immunol; 2021; 12():631797. PubMed ID: 33815382
[TBL] [Abstract][Full Text] [Related]
15. Antagonistic lipopolysaccharides block E. coli lipopolysaccharide function at human TLR4 via interaction with the human MD-2 lipopolysaccharide binding site.
Coats SR; Do CT; Karimi-Naser LM; Braham PH; Darveau RP
Cell Microbiol; 2007 May; 9(5):1191-202. PubMed ID: 17217428
[TBL] [Abstract][Full Text] [Related]
16. Identification of key residues that confer Rhodobacter sphaeroides LPS activity at horse TLR4/MD-2.
Irvine KL; Gangloff M; Walsh CM; Spring DR; Gay NJ; Bryant CE
PLoS One; 2014; 9(5):e98776. PubMed ID: 24879320
[TBL] [Abstract][Full Text] [Related]
17. Species-specific activation of TLR4 by hypoacylated endotoxins governed by residues 82 and 122 of MD-2.
Oblak A; Jerala R
PLoS One; 2014; 9(9):e107520. PubMed ID: 25203747
[TBL] [Abstract][Full Text] [Related]
18. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex.
Okamoto N; Mizote K; Honda H; Saeki A; Watanabe Y; Yamaguchi-Miyamoto T; Fukui R; Tanimura N; Motoi Y; Akashi-Takamura S; Kato T; Fujishita S; Kimura T; Ohto U; Shimizu T; Hirokawa T; Miyake K; Fukase K; Fujimoto Y; Nagai Y; Takatsu K
J Biol Chem; 2017 Sep; 292(37):15378-15394. PubMed ID: 28754693
[TBL] [Abstract][Full Text] [Related]
19. Human MD-2 discrimination of meningococcal lipid A structures and activation of TLR4.
Zimmer SM; Zughaier SM; Tzeng YL; Stephens DS
Glycobiology; 2007 Aug; 17(8):847-56. PubMed ID: 17545685
[TBL] [Abstract][Full Text] [Related]
20. Stable transduction of bovine TLR4 and bovine MD-2 into LPS-nonresponsive cells and soluble CD14 promote the ability to respond to LPS.
Sauter KS; Brcic M; Franchini M; Jungi TW
Vet Immunol Immunopathol; 2007 Jul; 118(1-2):92-104. PubMed ID: 17559944
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]