BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 25840825)

  • 1. Moderate DNA damage promotes metabolic flux into PPP via PKM2 Y-105 phosphorylation: a feature that favours cancer cells.
    Kumar B; Bamezai RN
    Mol Biol Rep; 2015 Aug; 42(8):1317-21. PubMed ID: 25840825
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyruvate Kinase M2 Modulates Esophageal Squamous Cell Carcinoma Chemotherapy Response by Regulating the Pentose Phosphate Pathway.
    Fukuda S; Miyata H; Miyazaki Y; Makino T; Takahashi T; Kurokawa Y; Yamasaki M; Nakajima K; Takiguchi S; Mori M; Doki Y
    Ann Surg Oncol; 2015 Dec; 22 Suppl 3():S1461-8. PubMed ID: 25808097
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lack of Evidence for PKM2 Protein Kinase Activity.
    Hosios AM; Fiske BP; Gui DY; Vander Heiden MG
    Mol Cell; 2015 Sep; 59(5):850-7. PubMed ID: 26300261
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of pyruvate kinase M2 and lactate dehydrogenase A by fibroblast growth factor receptor 1 in benign and malignant thyroid tissue.
    Kachel P; Trojanowicz B; Sekulla C; Prenzel H; Dralle H; Hoang-Vu C
    BMC Cancer; 2015 Mar; 15():140. PubMed ID: 25880801
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PKM2 contributes to cancer metabolism.
    Wong N; Ojo D; Yan J; Tang D
    Cancer Lett; 2015 Jan; 356(2 Pt A):184-91. PubMed ID: 24508027
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural insight into mechanisms for dynamic regulation of PKM2.
    Wang P; Sun C; Zhu T; Xu Y
    Protein Cell; 2015 Apr; 6(4):275-287. PubMed ID: 25645022
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glycolytic reprogramming in cancer cells: PKM2 dimer predominance induced by pulsatile PFK-1 activity.
    Shi X; You L; Luo RY
    Phys Biol; 2019 Sep; 16(6):066007. PubMed ID: 31469100
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic Kinase-Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem-like Cells.
    Zhou Z; Li M; Zhang L; Zhao H; Şahin Ö; Chen J; Zhao JJ; Songyang Z; Yu D
    Cancer Res; 2018 May; 78(9):2248-2261. PubMed ID: 29440169
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Role of PKM2 in Metabolic Reprogramming: Insights into the Regulatory Roles of Non-Coding RNAs.
    Puckett DL; Alquraishi M; Chowanadisai W; Bettaieb A
    Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33503959
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species.
    Yokoyama M; Tanuma N; Shibuya R; Shiroki T; Abue M; Yamamoto K; Miura K; Yamaguchi K; Sato I; Tamai K; Satoh K
    Int J Oncol; 2018 Mar; 52(3):881-891. PubMed ID: 29393401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PKM2 Thr454 phosphorylation increases its nuclear translocation and promotes xenograft tumor growth in A549 human lung cancer cells.
    Yu Z; Huang L; Qiao P; Jiang A; Wang L; Yang T; Tang S; Zhang W; Ren C
    Biochem Biophys Res Commun; 2016 May; 473(4):953-958. PubMed ID: 27045080
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma.
    Li C; Zhao Z; Zhou Z; Liu R
    Dig Dis Sci; 2016 Mar; 61(3):767-73. PubMed ID: 26500118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural Investigation of a Dimeric Variant of Pyruvate Kinase Muscle Isoform 2.
    Srivastava D; Razzaghi M; Henzl MT; Dey M
    Biochemistry; 2017 Dec; 56(50):6517-6520. PubMed ID: 29182273
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activators of PKM2 in cancer metabolism.
    Warner SL; Carpenter KJ; Bearss DJ
    Future Med Chem; 2014 Jun; 6(10):1167-78. PubMed ID: 25078136
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer.
    Chaneton B; Gottlieb E
    Trends Biochem Sci; 2012 Aug; 37(8):309-16. PubMed ID: 22626471
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The responsively decreased PKM2 facilitates the survival of pancreatic cancer cells in hypoglucose.
    Li X; Deng S; Liu M; Jin Y; Zhu S; Deng S; Chen J; He C; Qin Q; Wang C; Zhao G
    Cell Death Dis; 2018 Jan; 9(2):133. PubMed ID: 29374159
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The cysteine residue at 424th of pyruvate kinase M2 is crucial for tetramerization and responsiveness to oxidative stress.
    Masaki S; Hashimoto K; Kihara D; Tsuzuki C; Kataoka N; Suzuki K
    Biochem Biophys Res Commun; 2020 Jun; 526(4):973-977. PubMed ID: 32295714
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PKM2 depletion induces the compensation of glutaminolysis through β-catenin/c-Myc pathway in tumor cells.
    Wu H; Li Z; Yang P; Zhang L; Fan Y; Li Z
    Cell Signal; 2014 Nov; 26(11):2397-405. PubMed ID: 25041845
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23.
    Wei Y; Wang D; Jin F; Bian Z; Li L; Liang H; Li M; Shi L; Pan C; Zhu D; Chen X; Hu G; Liu Y; Zhang CY; Zen K
    Nat Commun; 2017 Jan; 8():14041. PubMed ID: 28067230
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyruvate kinase M2 interacts with DNA damage-binding protein 2 and reduces cell survival upon UV irradiation.
    Xie X; Wang M; Mei J; Hu F; Ding F; Lv L
    Biochem Biophys Res Commun; 2015 Nov; 467(2):427-33. PubMed ID: 26410533
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.