These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Pathogenic mechanism of a catecholaminergic polymorphic ventricular tachycardia causing-mutation in cardiac calcium release channel RyR2. Xiong J; Liu X; Gong Y; Zhang P; Qiang S; Zhao Q; Guo R; Qian Y; Wang L; Zhu L; Wang R; Hao Z; Wen H; Zhang J; Tang K; Zang WF; Yuchi Z; Chen H; Chen SRW; Zheng W; Wang SQ; Xu YW; Liu Z J Mol Cell Cardiol; 2018 Apr; 117():26-35. PubMed ID: 29477366 [TBL] [Abstract][Full Text] [Related]
6. Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance. Dixit SS; Wang T; Manzano EJ; Yoo S; Lee J; Chiang DY; Ryan N; Respress JL; Yechoor VK; Wehrens XH PLoS One; 2013; 8(3):e58655. PubMed ID: 23516528 [TBL] [Abstract][Full Text] [Related]
7. Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. Lehnart SE; Mongillo M; Bellinger A; Lindegger N; Chen BX; Hsueh W; Reiken S; Wronska A; Drew LJ; Ward CW; Lederer WJ; Kass RS; Morley G; Marks AR J Clin Invest; 2008 Jun; 118(6):2230-45. PubMed ID: 18483626 [TBL] [Abstract][Full Text] [Related]
8. Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor. Uchinoumi H; Yano M; Suetomi T; Ono M; Xu X; Tateishi H; Oda T; Okuda S; Doi M; Kobayashi S; Yamamoto T; Ikeda Y; Ohkusa T; Ikemoto N; Matsuzaki M Circ Res; 2010 Apr; 106(8):1413-24. PubMed ID: 20224043 [TBL] [Abstract][Full Text] [Related]
9. Glucose-Dependent Insulin Secretion in Pancreatic β-Cell Islets from Male Rats Requires Ca2+ Release via ROS-Stimulated Ryanodine Receptors. Llanos P; Contreras-Ferrat A; Barrientos G; Valencia M; Mears D; Hidalgo C PLoS One; 2015; 10(6):e0129238. PubMed ID: 26046640 [TBL] [Abstract][Full Text] [Related]
10. CPVT-associated cardiac ryanodine receptor mutation G357S with reduced penetrance impairs Ca2+ release termination and diminishes protein expression. Liu Y; Wei J; Wong King Yuen SM; Sun B; Tang Y; Wang R; Van Petegem F; Chen SRW PLoS One; 2017; 12(9):e0184177. PubMed ID: 28961276 [TBL] [Abstract][Full Text] [Related]
11. Cytosolic Ca2+-dependent Ca2+ release activity primarily determines the ER Ca2+ level in cells expressing the CPVT-linked mutant RYR2. Kurebayashi N; Murayama T; Ota R; Suzuki J; Kanemaru K; Kobayashi T; Ohno S; Horie M; Iino M; Yamashita F; Sakurai T J Gen Physiol; 2022 Sep; 154(9):. PubMed ID: 35446340 [TBL] [Abstract][Full Text] [Related]
12. Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes. George CH; Higgs GV; Lai FA Circ Res; 2003 Sep; 93(6):531-40. PubMed ID: 12919952 [TBL] [Abstract][Full Text] [Related]
13. Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death. Jiang D; Wang R; Xiao B; Kong H; Hunt DJ; Choi P; Zhang L; Chen SR Circ Res; 2005 Nov; 97(11):1173-81. PubMed ID: 16239587 [TBL] [Abstract][Full Text] [Related]
14. A novel ryanodine receptor mutation linked to sudden death increases sensitivity to cytosolic calcium. Meli AC; Refaat MM; Dura M; Reiken S; Wronska A; Wojciak J; Carroll J; Scheinman MM; Marks AR Circ Res; 2011 Jul; 109(3):281-90. PubMed ID: 21659649 [TBL] [Abstract][Full Text] [Related]
15. Involvement of the cardiac ryanodine receptor/calcium release channel in catecholaminergic polymorphic ventricular tachycardia. Marks AR; Priori S; Memmi M; Kontula K; Laitinen PJ J Cell Physiol; 2002 Jan; 190(1):1-6. PubMed ID: 11807805 [TBL] [Abstract][Full Text] [Related]
16. Role of ryanodine receptor mutations in cardiac pathology: more questions than answers? Thomas NL; George CH; Lai FA Biochem Soc Trans; 2006 Nov; 34(Pt 5):913-8. PubMed ID: 17052226 [TBL] [Abstract][Full Text] [Related]
17. Mechanisms of abnormal calcium homeostasis in mutations responsible for catecholaminergic polymorphic ventricular tachycardia. Iyer V; Hajjar RJ; Armoundas AA Circ Res; 2007 Feb; 100(2):e22-31. PubMed ID: 17234962 [TBL] [Abstract][Full Text] [Related]
18. Arrhythmogenesis in a catecholaminergic polymorphic ventricular tachycardia mutation that depresses ryanodine receptor function. Zhao YT; Valdivia CR; Gurrola GB; Powers PP; Willis BC; Moss RL; Jalife J; Valdivia HH Proc Natl Acad Sci U S A; 2015 Mar; 112(13):E1669-77. PubMed ID: 25775566 [TBL] [Abstract][Full Text] [Related]
19. Whole-exome sequencing in familial type 2 diabetes identifies an atypical missense variant in the RyR2 gene. Bansal V; Winkelmann BR; Dietrich JW; Boehm BO Front Endocrinol (Lausanne); 2024; 15():1258982. PubMed ID: 38444585 [TBL] [Abstract][Full Text] [Related]
20. Extensive Ca2+ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+ hypersensitivity. Uehara A; Murayama T; Yasukochi M; Fill M; Horie M; Okamoto T; Matsuura Y; Uehara K; Fujimoto T; Sakurai T; Kurebayashi N J Gen Physiol; 2017 Feb; 149(2):199-218. PubMed ID: 28082361 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]