178 related articles for article (PubMed ID: 25849925)
21. In Search of Small Molecules That Selectively Inhibit MBOAT4.
Murzinski ES; Saha I; Ding H; Strugatsky D; Hollibaugh RA; Liu H; Tontonoz P; Harran PG
Molecules; 2021 Dec; 26(24):. PubMed ID: 34946685
[TBL] [Abstract][Full Text] [Related]
22. Functional group and stereochemical requirements for substrate binding by ghrelin O-acyltransferase revealed by unnatural amino acid incorporation.
Cleverdon ER; Davis TR; Hougland JL
Bioorg Chem; 2018 Sep; 79():98-106. PubMed ID: 29738973
[TBL] [Abstract][Full Text] [Related]
23. The development of highly potent inhibitors for porcupine.
Wang X; Moon J; Dodge ME; Pan X; Zhang L; Hanson JM; Tuladhar R; Ma Z; Shi H; Williams NS; Amatruda JF; Carroll TJ; Lum L; Chen C
J Med Chem; 2013 Mar; 56(6):2700-4. PubMed ID: 23477365
[TBL] [Abstract][Full Text] [Related]
24. Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling.
Callier P; Calvel P; Matevossian A; Makrythanasis P; Bernard P; Kurosaka H; Vannier A; Thauvin-Robinet C; Borel C; Mazaud-Guittot S; Rolland A; Desdoits-Lethimonier C; Guipponi M; Zimmermann C; Stévant I; Kuhne F; Conne B; Santoni F; Lambert S; Huet F; Mugneret F; Jaruzelska J; Faivre L; Wilhelm D; Jégou B; Trainor PA; Resh MD; Antonarakis SE; Nef S
PLoS Genet; 2014 May; 10(5):e1004340. PubMed ID: 24784881
[TBL] [Abstract][Full Text] [Related]
25. Membrane topology of hedgehog acyltransferase.
Matevossian A; Resh MD
J Biol Chem; 2015 Jan; 290(4):2235-43. PubMed ID: 25488661
[TBL] [Abstract][Full Text] [Related]
26. Topological analysis of Hedgehog acyltransferase, a multipalmitoylated transmembrane protein.
Konitsiotis AD; Jovanović B; Ciepla P; Spitaler M; Lanyon-Hogg T; Tate EW; Magee AI
J Biol Chem; 2015 Feb; 290(6):3293-307. PubMed ID: 25505265
[TBL] [Abstract][Full Text] [Related]
27. Discovery of ghrelin o-acyltransferase.
Mohan H; Unniappan S
Endocr Dev; 2013; 25():16-24. PubMed ID: 23652388
[TBL] [Abstract][Full Text] [Related]
28. Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine
Rao DM; Shackleford MT; Bordeaux EK; Sottnik JL; Ferguson RL; Yamamoto TM; Wellberg EA; Bitler BG; Sikora MJ
J Biol Chem; 2019 Dec; 294(52):19950-19966. PubMed ID: 31740580
[TBL] [Abstract][Full Text] [Related]
29. Crystal structure of a membrane-bound O-acyltransferase.
Ma D; Wang Z; Merrikh CN; Lang KS; Lu P; Li X; Merrikh H; Rao Z; Xu W
Nature; 2018 Oct; 562(7726):286-290. PubMed ID: 30283133
[TBL] [Abstract][Full Text] [Related]
30. In Vitro Analysis of Hedgehog Acyltransferase and Porcupine Fatty Acyltransferase Activities.
Asciolla JJ; Rajanala K; Resh MD
Methods Mol Biol; 2019; 2009():243-255. PubMed ID: 31152409
[TBL] [Abstract][Full Text] [Related]
31. Palmitoylation of Hedgehog proteins by Hedgehog acyltransferase: roles in signalling and disease.
Resh MD
Open Biol; 2021 Mar; 11(3):200414. PubMed ID: 33653085
[TBL] [Abstract][Full Text] [Related]
32. Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides.
Yang J; Zhao TJ; Goldstein JL; Brown MS
Proc Natl Acad Sci U S A; 2008 Aug; 105(31):10750-5. PubMed ID: 18669668
[TBL] [Abstract][Full Text] [Related]
33. GOAT: the master switch for the ghrelin system?
Romero A; Kirchner H; Heppner K; Pfluger PT; Tschöp MH; Nogueiras R
Eur J Endocrinol; 2010 Jul; 163(1):1-8. PubMed ID: 20421334
[TBL] [Abstract][Full Text] [Related]
34. Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor.
Barnett BP; Hwang Y; Taylor MS; Kirchner H; Pfluger PT; Bernard V; Lin YY; Bowers EM; Mukherjee C; Song WJ; Longo PA; Leahy DJ; Hussain MA; Tschöp MH; Boeke JD; Cole PA
Science; 2010 Dec; 330(6011):1689-92. PubMed ID: 21097901
[TBL] [Abstract][Full Text] [Related]
35. Ghrelin octanoylation by ghrelin
Hougland JL
Biochem Soc Trans; 2019 Feb; 47(1):169-178. PubMed ID: 30626708
[TBL] [Abstract][Full Text] [Related]
36. Ghrelin O-acyltransferase (GOAT), a specific enzyme that modifies ghrelin with a medium-chain fatty acid.
Kojima M; Hamamoto A; Sato T
J Biochem; 2016 Oct; 160(4):189-194. PubMed ID: 27489223
[TBL] [Abstract][Full Text] [Related]
37. Ghrelin-O-acyltransferase (GOAT) acylates ghrelin in the hippocampus.
Isokawa M
Vitam Horm; 2022; 118():369-392. PubMed ID: 35180934
[TBL] [Abstract][Full Text] [Related]
38. An overview of ghrelin
Moose JE; Leets KA; Mate NA; Chisholm JD; Hougland JL
Expert Opin Ther Pat; 2020 Aug; 30(8):581-593. PubMed ID: 32564644
[TBL] [Abstract][Full Text] [Related]
39. Ghrelin O-acyltransferase assays and inhibition.
Taylor MS; Hwang Y; Hsiao PY; Boeke JD; Cole PA
Methods Enzymol; 2012; 514():205-28. PubMed ID: 22975055
[TBL] [Abstract][Full Text] [Related]
40. Attenuation of hedgehog acyltransferase-catalyzed sonic Hedgehog palmitoylation causes reduced signaling, proliferation and invasiveness of human carcinoma cells.
Konitsiotis AD; Chang SC; Jovanović B; Ciepla P; Masumoto N; Palmer CP; Tate EW; Couchman JR; Magee AI
PLoS One; 2014; 9(3):e89899. PubMed ID: 24608521
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
