BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

330 related articles for article (PubMed ID: 25851436)

  • 1. Deformability in the cleavage site of primary microRNA is not sensed by the double-stranded RNA binding domains in the microprocessor component DGCR8.
    Quarles KA; Chadalavada D; Showalter SA
    Proteins; 2015 Jun; 83(6):1165-79. PubMed ID: 25851436
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The core microprocessor component DiGeorge syndrome critical region 8 (DGCR8) is a nonspecific RNA-binding protein.
    Roth BM; Ishimaru D; Hennig M
    J Biol Chem; 2013 Sep; 288(37):26785-99. PubMed ID: 23893406
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.
    Partin AC; Zhang K; Jeong BC; Herrell E; Li S; Chiu W; Nam Y
    Mol Cell; 2020 May; 78(3):411-422.e4. PubMed ID: 32220646
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Helical defects in microRNA influence protein binding by TAR RNA binding protein.
    Acevedo R; Orench-Rivera N; Quarles KA; Showalter SA
    PLoS One; 2015; 10(1):e0116749. PubMed ID: 25608000
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex.
    Han J; Lee Y; Yeom KH; Nam JW; Heo I; Rhee JK; Sohn SY; Cho Y; Zhang BT; Kim VN
    Cell; 2006 Jun; 125(5):887-901. PubMed ID: 16751099
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional Anatomy of the Human Microprocessor.
    Nguyen TA; Jo MH; Choi YG; Park J; Kwon SC; Hohng S; Kim VN; Woo JS
    Cell; 2015 Jun; 161(6):1374-87. PubMed ID: 26027739
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dynamic origins of differential RNA binding function in two dsRBDs from the miRNA "microprocessor" complex.
    Wostenberg C; Quarles KA; Showalter SA
    Biochemistry; 2010 Dec; 49(50):10728-36. PubMed ID: 21073201
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Engineering double-stranded RNA binding activity into the Drosha double-stranded RNA binding domain results in a loss of microRNA processing function.
    Kranick JC; Chadalavada DM; Sahu D; Showalter SA
    PLoS One; 2017; 12(8):e0182445. PubMed ID: 28792523
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A heterotrimer model of the complete Microprocessor complex revealed by single-molecule subunit counting.
    Herbert KM; Sarkar SK; Mills M; Delgado De la Herran HC; Neuman KC; Steitz JA
    RNA; 2016 Feb; 22(2):175-83. PubMed ID: 26683315
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The DGCR8 RNA-binding heme domain recognizes primary microRNAs by clamping the hairpin.
    Quick-Cleveland J; Jacob JP; Weitz SH; Shoffner G; Senturia R; Guo F
    Cell Rep; 2014 Jun; 7(6):1994-2005. PubMed ID: 24910438
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Elucidating the Role of Microprocessor Protein DGCR8 in Bending RNA Structures.
    Pabit SA; Chen YL; Usher ET; Cook EC; Pollack L; Showalter SA
    Biophys J; 2020 Dec; 119(12):2524-2536. PubMed ID: 33189689
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs.
    Partin AC; Ngo TD; Herrell E; Jeong BC; Hon G; Nam Y
    Nat Commun; 2017 Nov; 8(1):1737. PubMed ID: 29170488
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of human Dicer-dsRBD in processing small regulatory RNAs.
    Wostenberg C; Lary JW; Sahu D; Acevedo R; Quarles KA; Cole JL; Showalter SA
    PLoS One; 2012; 7(12):e51829. PubMed ID: 23272173
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The N-terminal double-stranded RNA binding domains of Arabidopsis HYPONASTIC LEAVES1 are sufficient for pre-microRNA processing.
    Wu F; Yu L; Cao W; Mao Y; Liu Z; He Y
    Plant Cell; 2007 Mar; 19(3):914-25. PubMed ID: 17337628
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Backbone ¹HN, ¹³C, and ¹⁵N resonance assignments of the tandem RNA-binding domains of human DGCR8.
    Roth BM; Hennig M
    Biomol NMR Assign; 2013 Oct; 7(2):183-6. PubMed ID: 22752847
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Basis for pri-miRNA Recognition by Drosha.
    Jin W; Wang J; Liu CP; Wang HW; Xu RM
    Mol Cell; 2020 May; 78(3):423-433.e5. PubMed ID: 32220645
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genome-wide Mapping of DROSHA Cleavage Sites on Primary MicroRNAs and Noncanonical Substrates.
    Kim B; Jeong K; Kim VN
    Mol Cell; 2017 Apr; 66(2):258-269.e5. PubMed ID: 28431232
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular Basis for the Single-Nucleotide Precision of Primary microRNA Processing.
    Kwon SC; Baek SC; Choi YG; Yang J; Lee YS; Woo JS; Kim VN
    Mol Cell; 2019 Feb; 73(3):505-518.e5. PubMed ID: 30554947
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing.
    Yeom KH; Lee Y; Han J; Suh MR; Kim VN
    Nucleic Acids Res; 2006; 34(16):4622-9. PubMed ID: 16963499
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A central role for the primary microRNA stem in guiding the position and efficiency of Drosha processing of a viral pri-miRNA.
    Burke JM; Kelenis DP; Kincaid RP; Sullivan CS
    RNA; 2014 Jul; 20(7):1068-77. PubMed ID: 24854622
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.