BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 25854144)

  • 1. In silico analyses of missense mutations in coagulation factor VIII: identification of severity determinants of haemophilia A.
    Sengupta M; Sarkar D; Ganguly K; Sengupta D; Bhaskar S; Ray K
    Haemophilia; 2015 Sep; 21(5):662-9. PubMed ID: 25854144
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Haemophilia A mutations in patients with non-severe phenotype associated with a discrepancy between one-stage and chromogenic factor VIII activity assays.
    Pavlova A; Delev D; Pezeshkpoor B; Müller J; Oldenburg J
    Thromb Haemost; 2014 May; 111(5):851-61. PubMed ID: 24452774
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of factor VIII gene mutations in 101 patients with haemophilia A: mutation analysis by inversion screening and multiplex PCR and CSGE and molecular modelling of 10 novel missense substitutions.
    Jayandharan G; Shaji RV; Baidya S; Nair SC; Chandy M; Srivastava A
    Haemophilia; 2005 Sep; 11(5):481-91. PubMed ID: 16128892
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combined homology modelling and evolutionary significance evaluation of missense mutations in blood clotting factor VIII to highlight aspects of structure and function.
    Markoff A; Gerke V; Bogdanova N
    Haemophilia; 2009 Jul; 15(4):932-41. PubMed ID: 19473423
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of five associations of F8 missense mutations containing FVIII B domain mutations.
    Jourdy Y; Nougier C; Roualdes O; Fretigny M; Durand B; Negrier C; Vinciguerra C
    Haemophilia; 2016 Jul; 22(4):583-9. PubMed ID: 26915717
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In silico calculated affinity of FVIII-derived peptides for HLA class II alleles predicts inhibitor development in haemophilia A patients with missense mutations in the F8 gene.
    Pashov AD; Calvez T; Gilardin L; Maillère B; Repessé Y; Oldenburg J; Pavlova A; Kaveri SV; Lacroix-Desmazes S
    Haemophilia; 2014 Mar; 20(2):176-84. PubMed ID: 24118514
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In silico and in vitro evaluation of the impact of mutations in non-severe haemophilia A patients on assay discrepancies.
    Pezeshkpoor B; Gazorpak M; Berkemeier AC; Singer H; Pavlova A; Biswas A; Oldenburg J
    Ann Hematol; 2019 Aug; 98(8):1855-1865. PubMed ID: 30997536
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Study of mutations in Jordanian patients with haemophilia A: identification of five novel mutations.
    Awidi A; Ramahi M; Alhattab D; Mefleh R; Dweiri M; Bsoul N; Magablah A; Arafat E; Barqawi M; Bishtawi M; Haddadeen E; Falah M; Tarawneh B; Swaidan S; Fauori S
    Haemophilia; 2010 Jan; 16(1):136-42. PubMed ID: 19817879
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thirteen novel mutations in the factor VIII gene in the Nijmegen haemophilia A patient population.
    Boekhorst J; Verbruggen B; Lavergne JM; Costa JM; Schoormans SC; Brons PP; van Kraaij MG; Nováková IR; van Heerde WL
    Br J Haematol; 2005 Oct; 131(1):109-17. PubMed ID: 16173970
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Unveiling the influence of factor VIII physicochemical properties on hemophilia A phenotype through an in silico methodology.
    Meireles MR; Stelmach LH; Bandinelli E; Vieira GF
    Comput Methods Programs Biomed; 2022 Jun; 219():106768. PubMed ID: 35367915
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for hemophilia A caused by mutations in the C domains of blood coagulation factor VIII.
    Gale AJ; Pellequer JL; Getzoff ED; Griffin JH
    Thromb Haemost; 2000 Jan; 83(1):78-85. PubMed ID: 10669159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Detection of 95 novel mutations in coagulation factor VIII gene F8 responsible for hemophilia A: results from a single institution.
    Guillet B; Lambert T; d'Oiron R; Proulle V; Plantier JL; Rafowicz A; Peynet J; Costa JM; Bendelac L; Laurian Y; Lavergne JM
    Hum Mutat; 2006 Jul; 27(7):676-85. PubMed ID: 16786531
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Factor VIII (FVIII) gene mutations in 120 patients with hemophilia A: detection of 26 novel mutations and correlation with FVIII inhibitor development.
    Repessé Y; Slaoui M; Ferrandiz D; Gautier P; Costa C; Costa JM; Lavergne JM; Borel-Derlon A
    J Thromb Haemost; 2007 Jul; 5(7):1469-76. PubMed ID: 17445092
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutation analysis in 51 patients with haemophilia A: report of 10 novel mutations and correlations between genotype and clinical phenotype.
    Hill M; Deam S; Gordon B; Dolan G
    Haemophilia; 2005 Mar; 11(2):133-41. PubMed ID: 15810915
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of F8 B domain gene variants on synthesis, secretion, activity and stability of factor VIII protein.
    Pahl S; Pavlova A; Driesen J; Oldenburg J
    Thromb Haemost; 2014 Jan; 111(1):58-66. PubMed ID: 24108539
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A large-scale computational study of inhibitor risk in non-severe haemophilia A.
    Shepherd AJ; Skelton S; Sansom CE; Gomez K; Moss DS; Hart DP
    Br J Haematol; 2015 Feb; 168(3):413-20. PubMed ID: 25244644
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular diagnosis of haemophilia A at Centro Hospitalar de Coimbra in Portugal: study of 103 families--15 new mutations.
    Silva Pinto C; Fidalgo T; Salvado R; Marques D; Gonçalves E; Martinho P; Markoff A; Martins N; Letícia Ribeiro M
    Haemophilia; 2012 Jan; 18(1):129-38. PubMed ID: 21645180
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Significance of F8 missense mutations with respect to inhibitor formation.
    Schwaab R; Pavlova A; Albert T; Caspers M; Oldenburg J
    Thromb Haemost; 2013 Mar; 109(3):464-70. PubMed ID: 23306409
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Factor VIII inhibitors in two families with mild haemophilia A: structural analysis of the mutations.
    Knobe KE; Villoutreix BO; Tengborn LI; Petrini P; Ljung RC
    Haemostasis; 2000; 30(5):268-79. PubMed ID: 11251334
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Seven novel and four recurrent point mutations in the factor VIII (F8C) gene.
    Bogdanova N; Lemcke B; Markoff A; Pollmann H; Dworniczak B; Eigel A; Horst J
    Hum Mutat; 2001 Dec; 18(6):546. PubMed ID: 11748850
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.