100 related articles for article (PubMed ID: 25855483)
1. Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer.
Kümler I; Balslev E; Poulsen TS; Nielsen SL; Nygård SB; Rømer MU; Christensen IJ; Høgdall E; Moreira J; Nielsen DL; Brünner N; Stenvang J
Int J Cancer; 2015 Oct; 137(8):2000-6. PubMed ID: 25855483
[TBL] [Abstract][Full Text] [Related]
2. TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas.
Grunnet M; Calatayud D; Schultz NA; Hasselby JP; Mau-Sørensen M; Brünner N; Stenvang J
Scand J Gastroenterol; 2015 Apr; 50(4):485-94. PubMed ID: 25615400
[TBL] [Abstract][Full Text] [Related]
3. Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort.
Smith DH; Christensen IJ; Jensen NF; Markussen B; Rømer MU; Nygård SB; Müller S; Nielsen HJ; Brünner N; Nielsen KV
PLoS One; 2013; 8(4):e60613. PubMed ID: 23577133
[TBL] [Abstract][Full Text] [Related]
4. Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer.
Palshof JA; Høgdall EV; Poulsen TS; Linnemann D; Jensen BV; Pfeiffer P; Tarpgaard LS; Brünner N; Stenvang J; Yilmaz M; Nielsen DL
BMC Cancer; 2017 Jan; 17(1):48. PubMed ID: 28077117
[TBL] [Abstract][Full Text] [Related]
5. Assessment of the topoisomerase I gene copy number as a predictive biomarker of objective response to irinotecan in metastatic colorectal cancer.
Nygård SB; Christensen IJ; Nielsen SL; Nielsen HJ; Brünner N; Spindler KL
Scand J Gastroenterol; 2014 Jan; 49(1):84-91. PubMed ID: 24256029
[TBL] [Abstract][Full Text] [Related]
6. Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers.
Sønderstrup IM; Nygård SB; Poulsen TS; Linnemann D; Stenvang J; Nielsen HJ; Bartek J; Brünner N; Nørgaard P; Riis L
Mol Oncol; 2015 Jun; 9(6):1207-17. PubMed ID: 25777966
[TBL] [Abstract][Full Text] [Related]
7. TOP1 gene copy numbers in colorectal cancer samples and cell lines and their association to in vitro drug sensitivity.
Rømer MU; Jensen NF; Nielsen SL; Müller S; Nielsen KV; Nielsen HJ; Brünner N
Scand J Gastroenterol; 2012 Jan; 47(1):68-79. PubMed ID: 22171973
[TBL] [Abstract][Full Text] [Related]
8. Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis.
Rømer MU; Nygård SB; Christensen IJ; Nielsen SL; Nielsen KV; Müller S; Smith DH; Vainer B; Nielsen HJ; Brünner N
Mol Oncol; 2013 Feb; 7(1):101-11. PubMed ID: 23110915
[TBL] [Abstract][Full Text] [Related]
9. Lack of topoisomerase copy number changes in patients with de novo and relapsed diffuse large B-cell lymphoma.
Pedersen MØ; Poulsen TS; Gang AO; Knudsen H; Lauritzen AF; Pedersen M; Nielsen SL; Brown P; Høgdall E; Nørgaard P
Exp Hematol; 2015 Jul; 43(7):534-6. PubMed ID: 25931012
[TBL] [Abstract][Full Text] [Related]
10. Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study.
Tesauro C; Simonsen AK; Andersen MB; Petersen KW; Kristoffersen EL; Algreen L; Hansen NY; Andersen AB; Jakobsen AK; Stougaard M; Gromov P; Knudsen BR; Gromova I
BMC Cancer; 2019 Nov; 19(1):1158. PubMed ID: 31783818
[TBL] [Abstract][Full Text] [Related]
11. DNA Topoisomerase I Gene Copy Number and mRNA Expression Assessed as Predictive Biomarkers for Adjuvant Irinotecan in Stage II/III Colon Cancer.
Nygård SB; Vainer B; Nielsen SL; Bosman F; Tejpar S; Roth A; Delorenzi M; Brünner N; Budinska E
Clin Cancer Res; 2016 Apr; 22(7):1621-31. PubMed ID: 26542057
[TBL] [Abstract][Full Text] [Related]
12. A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol.
Kümler I; Balslev E; Stenvang J; Brünner N; Nielsen D
BMC Cancer; 2015 Feb; 15():78. PubMed ID: 25885574
[TBL] [Abstract][Full Text] [Related]
13. Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations.
Jensen NF; Agama K; Roy A; Smith DH; Pfister TD; Rømer MU; Zhang HL; Doroshow JH; Knudsen BR; Stenvang J; Brünner N; Pommier Y
J Exp Clin Cancer Res; 2016 Mar; 35():56. PubMed ID: 27029323
[TBL] [Abstract][Full Text] [Related]
14. Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase I gene.
Kümler I; Balslev E; Stenvang J; Brünner N; Ejlertsen B; Jakobsen EH; Nielsen DL
BMC Cancer; 2019 Jun; 19(1):573. PubMed ID: 31196001
[TBL] [Abstract][Full Text] [Related]
15. Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein in human breast tumor samples.
Mueller RE; Parkes RK; Andrulis I; O'Malley FP
Genes Chromosomes Cancer; 2004 Apr; 39(4):288-97. PubMed ID: 14978790
[TBL] [Abstract][Full Text] [Related]
16. Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis.
Ryan D; Rafferty M; Hegarty S; O'Leary P; Faller W; Gremel G; Bergqvist M; Agnarsdottir M; Strömberg S; Kampf C; Pontén F; Millikan RC; Dervan PA; Gallagher WM
Pigment Cell Melanoma Res; 2010 Aug; 23(4):542-53. PubMed ID: 20465595
[TBL] [Abstract][Full Text] [Related]
17. Absence of chromosome 17 polysomy in breast cancer: analysis by CEP17 chromogenic in situ hybridization and multiplex ligation-dependent probe amplification.
Moelans CB; de Weger RA; van Diest PJ
Breast Cancer Res Treat; 2010 Feb; 120(1):1-7. PubMed ID: 19760503
[TBL] [Abstract][Full Text] [Related]
18. Characterization of the topoisomerase I locus in human colorectal cancer.
Boonsong A; Marsh S; Rooney PH; Stevenson DA; Cassidy J; McLeod HL
Cancer Genet Cytogenet; 2000 Aug; 121(1):56-60. PubMed ID: 10958942
[TBL] [Abstract][Full Text] [Related]
19. Underpinning the repurposing of anthracyclines towards colorectal cancer: assessment of topoisomerase II alpha gene copy number alterations in colorectal cancer.
Nygård SB; Christensen IJ; Smith DH; Nielsen SL; Jensen NF; Nielsen HJ; Vainer B; Brünner N
Scand J Gastroenterol; 2013 Dec; 48(12):1436-43. PubMed ID: 24138107
[TBL] [Abstract][Full Text] [Related]
20. Characterization of topoisomerase II alpha gene amplification and deletion in breast cancer.
Järvinen TA; Tanner M; Bärlund M; Borg A; Isola J
Genes Chromosomes Cancer; 1999 Oct; 26(2):142-50. PubMed ID: 10469452
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]