These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

351 related articles for article (PubMed ID: 25855750)

  • 1. Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity.
    Smith EC; Case JB; Blanc H; Isakov O; Shomron N; Vignuzzi M; Denison MR
    J Virol; 2015 Jun; 89(12):6418-26. PubMed ID: 25855750
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Homology-Based Identification of a Mutation in the Coronavirus RNA-Dependent RNA Polymerase That Confers Resistance to Multiple Mutagens.
    Sexton NR; Smith EC; Blanc H; Vignuzzi M; Peersen OB; Denison MR
    J Virol; 2016 Aug; 90(16):7415-7428. PubMed ID: 27279608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations.
    Graepel KW; Lu X; Case JB; Sexton NR; Smith EC; Denison MR
    mBio; 2017 Nov; 8(6):. PubMed ID: 29114026
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.
    Eckerle LD; Lu X; Sperry SM; Choi L; Denison MR
    J Virol; 2007 Nov; 81(22):12135-44. PubMed ID: 17804504
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Murine Hepatitis Virus nsp14 Exoribonuclease Activity Is Required for Resistance to Innate Immunity.
    Case JB; Li Y; Elliott R; Lu X; Graepel KW; Sexton NR; Smith EC; Weiss SR; Denison MR
    J Virol; 2018 Jan; 92(1):. PubMed ID: 29046453
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteolytic Processing of the Coronavirus Replicase Nonstructural Protein 14 Exonuclease Is Not Required for Virus Replication but Alters RNA Synthesis and Viral Fitness.
    Anderson-Daniels J; Gribble J; Denison M
    J Virol; 2022 Aug; 96(16):e0084122. PubMed ID: 35924922
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The coronavirus nsp14 exoribonuclease interface with the cofactor nsp10 is essential for efficient virus replication and enzymatic activity.
    Grimes SL; Heaton BE; Anderson ML; Burke K; Stevens L; Lu X; Heaton NS; Denison MR; Anderson-Daniels J
    bioRxiv; 2024 Sep; ():. PubMed ID: 39386528
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2.
    Ogando NS; Zevenhoven-Dobbe JC; van der Meer Y; Bredenbeek PJ; Posthuma CC; Snijder EJ
    J Virol; 2020 Nov; 94(23):. PubMed ID: 32938769
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics.
    Smith EC; Blanc H; Surdel MC; Vignuzzi M; Denison MR
    PLoS Pathog; 2013 Aug; 9(8):e1003565. PubMed ID: 23966862
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.
    Case JB; Ashbrook AW; Dermody TS; Denison MR
    J Virol; 2016 Aug; 90(16):7248-7256. PubMed ID: 27252528
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
    Ferron F; Subissi L; Silveira De Morais AT; Le NTT; Sevajol M; Gluais L; Decroly E; Vonrhein C; Bricogne G; Canard B; Imbert I
    Proc Natl Acad Sci U S A; 2018 Jan; 115(2):E162-E171. PubMed ID: 29279395
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.
    Becares M; Pascual-Iglesias A; Nogales A; Sola I; Enjuanes L; Zuñiga S
    J Virol; 2016 Jun; 90(11):5399-5414. PubMed ID: 27009949
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Computational Study on the Interaction of NSP10 and NSP14: Unraveling the RNA Synthesis Proofreading Mechanism in SARS-CoV-2, SARS-CoV, and MERS-CoV.
    Sarma H; Sastry GN
    ACS Omega; 2022 Aug; 7(34):30003-30022. PubMed ID: 36035077
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Small-Molecule Antiviral β-d-
    Agostini ML; Pruijssers AJ; Chappell JD; Gribble J; Lu X; Andres EL; Bluemling GR; Lockwood MA; Sheahan TP; Sims AC; Natchus MG; Saindane M; Kolykhalov AA; Painter GR; Baric RS; Denison MR
    J Virol; 2019 Dec; 93(24):. PubMed ID: 31578288
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
    Baddock HT; Brolih S; Yosaatmadja Y; Ratnaweera M; Bielinski M; Swift LP; Cruz-Migoni A; Fan H; Keown JR; Walker AP; Morris GM; Grimes JM; Fodor E; Schofield CJ; Gileadi O; McHugh PJ
    Nucleic Acids Res; 2022 Feb; 50(3):1484-1500. PubMed ID: 35037045
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.
    Agostini ML; Andres EL; Sims AC; Graham RL; Sheahan TP; Lu X; Smith EC; Case JB; Feng JY; Jordan R; Ray AS; Cihlar T; Siegel D; Mackman RL; Clarke MO; Baric RS; Denison MR
    mBio; 2018 Mar; 9(2):. PubMed ID: 29511076
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of the SARS-CoV-2 NSP14 3'-5' exoribonuclease by NSP10 and response to antiviral inhibitors.
    Riccio AA; Sullivan ED; Copeland WC
    J Biol Chem; 2022 Jan; 298(1):101518. PubMed ID: 34942146
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New targets for drug design: importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2.
    Saramago M; Bárria C; Costa VG; Souza CS; Viegas SC; Domingues S; Lousa D; Soares CM; Arraiano CM; Matos RG
    FEBS J; 2021 Sep; 288(17):5130-5147. PubMed ID: 33705595
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN.
    Moeller NH; Shi K; Demir Ö; Belica C; Banerjee S; Yin L; Durfee C; Amaro RE; Aihara H
    Proc Natl Acad Sci U S A; 2022 Mar; 119(9):. PubMed ID: 35165203
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Processing of open reading frame 1a replicase proteins nsp7 to nsp10 in murine hepatitis virus strain A59 replication.
    Deming DJ; Graham RL; Denison MR; Baric RS
    J Virol; 2007 Oct; 81(19):10280-91. PubMed ID: 17634238
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.