BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

529 related articles for article (PubMed ID: 25860930)

  • 1. The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1.
    Liu W; Yue F; Zheng M; Merlot A; Bae DH; Huang M; Lane D; Jansson P; Lui GY; Richardson V; Sahni S; Kalinowski D; Kovacevic Z; Richardson DR
    Oncotarget; 2015 Apr; 6(11):8851-74. PubMed ID: 25860930
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
    Wangpu X; Lu J; Xi R; Yue F; Sahni S; Park KC; Menezes S; Huang ML; Zheng M; Kovacevic Z; Richardson DR
    Mol Pharmacol; 2016 May; 89(5):521-40. PubMed ID: 26895766
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Src activation regulates anoikis in human colon tumor cell lines.
    Windham TC; Parikh NU; Siwak DR; Summy JM; McConkey DJ; Kraker AJ; Gallick GE
    Oncogene; 2002 Nov; 21(51):7797-807. PubMed ID: 12420216
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Src regulates phorbol 12-myristate 13-acetate-activated PKC-induced migration via Cas/Crk/Rac1 signaling pathway in glioblastoma cells.
    Nomura N; Nomura M; Sugiyama K; Hamada J
    Int J Mol Med; 2007 Oct; 20(4):511-9. PubMed ID: 17786281
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
    Kovacevic Z; Menezes SV; Sahni S; Kalinowski DS; Bae DH; Lane DJ; Richardson DR
    J Biol Chem; 2016 Jan; 291(3):1029-52. PubMed ID: 26534963
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Requirement of the p130CAS-Crk coupling for metastasis suppressor KAI1/CD82-mediated inhibition of cell migration.
    Zhang XA; He B; Zhou B; Liu L
    J Biol Chem; 2003 Jul; 278(29):27319-28. PubMed ID: 12738793
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways.
    Kovacevic Z; Chikhani S; Lui GY; Sivagurunathan S; Richardson DR
    Antioxid Redox Signal; 2013 Mar; 18(8):874-87. PubMed ID: 22462691
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway.
    Sun J; Zhang D; Zheng Y; Zhao Q; Zheng M; Kovacevic Z; Richardson DR
    Mol Pharmacol; 2013 Feb; 83(2):454-69. PubMed ID: 23188716
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms.
    Kovacevic Z; Sivagurunathan S; Mangs H; Chikhani S; Zhang D; Richardson DR
    Carcinogenesis; 2011 May; 32(5):732-40. PubMed ID: 21398495
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of β-catenin through mechanisms involving FRAT1 and PAK4.
    Jin R; Liu W; Menezes S; Yue F; Zheng M; Kovacevic Z; Richardson DR
    J Cell Sci; 2014 Jul; 127(Pt 14):3116-30. PubMed ID: 24829151
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NDRG1 and CRK-I/II are regulators of endothelial cell migration under Intermittent Hypoxia.
    Toffoli S; Delaive E; Dieu M; Feron O; Raes M; Michiels C
    Angiogenesis; 2009; 12(4):339-54. PubMed ID: 19760510
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oncogenic MNK signalling regulates the metastasis suppressor NDRG1.
    Tian S; Wang X; Proud CG
    Oncotarget; 2017 Jul; 8(28):46121-46135. PubMed ID: 28545025
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells.
    Dixon KM; Lui GY; Kovacevic Z; Zhang D; Yao M; Chen Z; Dong Q; Assinder SJ; Richardson DR
    Br J Cancer; 2013 Feb; 108(2):409-19. PubMed ID: 23287991
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective involvement of p130Cas/Crk/Pyk2/c-Src in endothelin-1-induced JNK activation.
    Kodama H; Fukuda K; Takahashi E; Tahara S; Tomita Y; Ieda M; Kimura K; Owada KM; Vuori K; Ogawa S
    Hypertension; 2003 Jun; 41(6):1372-9. PubMed ID: 12719447
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.
    Servitja JM; Marinissen MJ; Sodhi A; Bustelo XR; Gutkind JS
    J Biol Chem; 2003 Sep; 278(36):34339-46. PubMed ID: 12810717
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.
    Fang BA; Kovačević Ž; Park KC; Kalinowski DS; Jansson PJ; Lane DJ; Sahni S; Richardson DR
    Biochim Biophys Acta; 2014 Jan; 1845(1):1-19. PubMed ID: 24269900
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity.
    Cardoso AP; Pinto ML; Pinto AT; Oliveira MI; Pinto MT; Gonçalves R; Relvas JB; Figueiredo C; Seruca R; Mantovani A; Mareel M; Barbosa MA; Oliveira MJ
    Oncogene; 2014 Apr; 33(16):2123-33. PubMed ID: 23644655
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation.
    Watanabe T; Tsuda M; Tanaka S; Ohba Y; Kawaguchi H; Majima T; Sawa H; Minami A
    Mol Cancer Res; 2009 Sep; 7(9):1582-92. PubMed ID: 19737974
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.
    Feng H; Hu B; Liu KW; Li Y; Lu X; Cheng T; Yiin JJ; Lu S; Keezer S; Fenton T; Furnari FB; Hamilton RL; Vuori K; Sarkaria JN; Nagane M; Nishikawa R; Cavenee WK; Cheng SY
    J Clin Invest; 2011 Dec; 121(12):4670-84. PubMed ID: 22080864
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion.
    Sharma A; Mendonca J; Ying J; Kim HS; Verdone JE; Zarif JC; Carducci M; Hammers H; Pienta KJ; Kachhap S
    Mol Oncol; 2017 Jun; 11(6):655-669. PubMed ID: 28371345
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.