These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

86 related articles for article (PubMed ID: 25862201)

  • 1. Structure-activity relationships of IKM-159: Diverted synthesis and biological evaluation of a series of C5-oxy analogs.
    Chiba M; Fujimoto C; Sakai R; Oikawa M
    Bioorg Med Chem Lett; 2015 May; 25(9):1869-71. PubMed ID: 25862201
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization.
    Juknaitė L; Sugamata Y; Tokiwa K; Ishikawa Y; Takamizawa S; Eng A; Sakai R; Pickering DS; Frydenvang K; Swanson GT; Kastrup JS; Oikawa M
    J Med Chem; 2013 Mar; 56(6):2283-93. PubMed ID: 23432124
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lewis Acid Catalyzed Annulation of Donor-Acceptor Cyclopropane and N-Tosylaziridinedicarboxylate: One-Step Synthesis of Functionalized 2H-Furo[2,3-c]pyrroles.
    Ghosh A; Pandey AK; Banerjee P
    J Org Chem; 2015 Jul; 80(14):7235-42. PubMed ID: 26090694
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of conformationally constrained analogs of the antitumor agents XK469 and SH80. Part 5.
    Hazeldine ST; Polin L; Kushner J; White K; Corbett TH; Horwitz JP
    Bioorg Med Chem; 2006 Apr; 14(7):2462-7. PubMed ID: 16337128
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stereostructure-activity studies on agonists at the AMPA and kainate subtypes of ionotropic glutamate receptors.
    Johansen TN; Greenwood JR; Frydenvang K; Madsen U; Krogsgaard-Larsen P
    Chirality; 2003 Feb; 15(2):167-79. PubMed ID: 12520509
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological activity of n-butylphthalide derivatives.
    Wang W; Cha XX; Reiner J; Gao Y; Qiao HL; Shen JX; Chang JB
    Eur J Med Chem; 2010 May; 45(5):1941-6. PubMed ID: 20133025
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pyrrolidinones as potent functional antagonists of the human melanocortin-4 receptor.
    Jiang W; Tucci FC; Tran JA; Fleck BA; Wen J; Markison S; Marinkovic D; Chen CW; Arellano M; Hoare SR; Johns M; Foster AC; Saunders J; Chen C
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5610-3. PubMed ID: 17822895
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rapid and efficient synthesis of dysiherbaine and analogues to explore structure-activity relationships.
    Sasaki M; Tsubone K; Aoki K; Akiyama N; Shoji M; Oikawa M; Sakai R; Shimamoto K
    J Org Chem; 2008 Jan; 73(1):264-73. PubMed ID: 18052390
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tricyclic pyrazoles. Part 6. Benzofuro[3,2-c]pyrazole: a versatile architecture for CB2 selective ligands.
    Pinna G; Loriga G; Lazzari P; Ruiu S; Falzoi M; Frau S; Pau A; Murineddu G; Asproni B; Pinna GA
    Eur J Med Chem; 2014 Jul; 82():281-92. PubMed ID: 24922543
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships.
    Falch E; Brehm L; Mikkelsen I; Johansen TN; Skjaerbaek N; Nielsen B; Stensbøl TB; Ebert B; Krogsgaard-Larsen P
    J Med Chem; 1998 Jul; 41(14):2513-23. PubMed ID: 9651156
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1,2,4-Benzothiadiazine-1,1-dioxide derivatives as ionotropic glutamate receptor ligands: synthesis and structure-activity relationships.
    Varano F; Catarzi D; Colotta V; Squarcialupi L; Matucci R
    Arch Pharm (Weinheim); 2014 Nov; 347(11):777-85. PubMed ID: 25204434
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of novel metalloproteinase inhibitors.
    Nakatani S; Ikura M; Yamamoto S; Nishita Y; Itadani S; Habashita H; Sugiura T; Ogawa K; Ohno H; Takahashi K; Nakai H; Toda M
    Bioorg Med Chem; 2006 Aug; 14(15):5402-22. PubMed ID: 16621578
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyrrolidinones as orally bioavailable antagonists of the human melanocortin-4 receptor with anti-cachectic activity.
    Tran JA; Tucci FC; Jiang W; Marinkovic D; Chen CW; Arellano M; Markison S; Fleck BA; Wen J; White NS; Pontillo J; Saunders J; Marks D; Hoare SR; Madan A; Foster AC; Chen C
    Bioorg Med Chem; 2007 Aug; 15(15):5166-76. PubMed ID: 17544282
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacological characterization of (4R)-alkyl glutamate analogues at the ionotropic glutamate receptors--focus on subtypes iGlu(5-7).
    Bunch L; Gefflaut T; Alaux S; Sagot E; Nielsen B; Pickering DS
    Eur J Pharmacol; 2009 May; 609(1-3):1-4. PubMed ID: 19285062
    [TBL] [Abstract][Full Text] [Related]  

  • 15. (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.
    Brehm L; Greenwood JR; Hansen KB; Nielsen B; Egebjerg J; Stensbøl TB; Bräuner-Osborne H; Sløk FA; Kronborg TT; Krogsgaard-Larsen P
    J Med Chem; 2003 Apr; 46(8):1350-8. PubMed ID: 12672235
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antiproliferative activity of benzofuran-based analogs of cercosporamide against non-small cell lung cancer cell lines.
    Bazin MA; Bodero L; Tomasoni C; Rousseau B; Roussakis C; Marchand P
    Eur J Med Chem; 2013 Nov; 69():823-32. PubMed ID: 24121233
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthetic studies on selective adenosine A2A receptor antagonists. Part II: synthesis and structure-activity relationships of novel benzofuran derivatives.
    Saku O; Saki M; Kurokawa M; Ikeda K; Uchida S; Takizawa T; Uesaka N
    Bioorg Med Chem Lett; 2010 Jun; 20(12):3768-71. PubMed ID: 20483600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptors.
    Poulsen MH; Lucas S; Bach TB; Barslund AF; Wenzler C; Jensen CB; Kristensen AS; Strømgaard K
    J Med Chem; 2013 Feb; 56(3):1171-81. PubMed ID: 23320429
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationships of precursors and analogs of natural 3-enoyl-tetramic acids.
    Barnickel B; Bayliffe F; Diestel R; Kempf K; Laschat S; Pachali S; Sasse F; Schlenk A; Schobert R
    Chem Biodivers; 2010 Dec; 7(12):2830-45. PubMed ID: 21161996
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and pharmacology of highly selective carboxy and phosphono isoxazole amino acid AMPA receptor antagonists.
    Madsen U; Bang-Andersen B; Brehm L; Christensen IT; Ebert B; Kristoffersen IT; Lang Y; Krogsgaard-Larsen P
    J Med Chem; 1996 Apr; 39(8):1682-91. PubMed ID: 8648608
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.