BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 25865359)

  • 1. Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties.
    Poletto M; Malfatti MC; Dorjsuren D; Scognamiglio PL; Marasco D; Vascotto C; Jadhav A; Maloney DJ; Wilson DM; Simeonov A; Tell G
    Mol Carcinog; 2016 May; 55(5):688-704. PubMed ID: 25865359
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC.
    Malfatti MC; Gerratana L; Dalla E; Isola M; Damante G; Di Loreto C; Puglisi F; Tell G
    J Exp Clin Cancer Res; 2019 Jul; 38(1):309. PubMed ID: 31307523
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.
    Vascotto C; Lirussi L; Poletto M; Tiribelli M; Damiani D; Fabbro D; Damante G; Demple B; Colombo E; Tell G
    Oncogene; 2014 May; 33(22):2876-87. PubMed ID: 23831574
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nucleophosmin interaction with APE1: Insights into DNA repair regulation.
    López DJ; de Blas A; Hurtado M; García-Alija M; Mentxaka J; de la Arada I; Urbaneja MA; Alonso-Mariño M; Bañuelos S
    DNA Repair (Amst); 2020 Apr; 88():102809. PubMed ID: 32092641
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression and prognostic significance of APE1/Ref-1 and NPM1 proteins in high-grade ovarian serous cancer.
    Londero AP; Orsaria M; Tell G; Marzinotto S; Capodicasa V; Poletto M; Vascotto C; Sacco C; Mariuzzi L
    Am J Clin Pathol; 2014 Mar; 141(3):404-14. PubMed ID: 24515769
    [TBL] [Abstract][Full Text] [Related]  

  • 6. APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.
    Vascotto C; Fantini D; Romanello M; Cesaratto L; Deganuto M; Leonardi A; Radicella JP; Kelley MR; D'Ambrosio C; Scaloni A; Quadrifoglio F; Tell G
    Mol Cell Biol; 2009 Apr; 29(7):1834-54. PubMed ID: 19188445
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1).
    Laev SS; Salakhutdinov NF; Lavrik OI
    Bioorg Med Chem; 2017 May; 25(9):2531-2544. PubMed ID: 28161249
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Diverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collection.
    Dorjsuren D; Kim D; Vyjayanti VN; Maloney DJ; Jadhav A; Wilson DM; Simeonov A
    PLoS One; 2012; 7(10):e47974. PubMed ID: 23110144
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway.
    Codrich M; Comelli M; Malfatti MC; Mio C; Ayyildiz D; Zhang C; Kelley MR; Terrosu G; Pucillo CEM; Tell G
    DNA Repair (Amst); 2019 Oct; 82():102675. PubMed ID: 31450087
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Receptor-based virtual screening and biological characterization of human apurinic/apyrimidinic endonuclease (Ape1) inhibitors.
    Ruiz FM; Francis SM; Tintoré M; Ferreira R; Gil-Redondo R; Morreale A; Ortiz ÁR; Eritja R; Fàbrega C
    ChemMedChem; 2012 Dec; 7(12):2168-78. PubMed ID: 23109358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins.
    Poletto M; Lirussi L; Wilson DM; Tell G
    Mol Biol Cell; 2014 May; 25(10):1641-52. PubMed ID: 24648491
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.
    Bapat A; Glass LS; Luo M; Fishel ML; Long EC; Georgiadis MM; Kelley MR
    J Pharmacol Exp Ther; 2010 Sep; 334(3):988-98. PubMed ID: 20504914
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The expression profile and prognostic value of APE/Ref-1 and NPM1 in high-grade serous ovarian adenocarcinoma.
    Fan X; Wen L; Li Y; Lou L; Liu W; Zhang J
    APMIS; 2017 Oct; 125(10):857-862. PubMed ID: 28766835
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair.
    Sengupta S; Mantha AK; Song H; Roychoudhury S; Nath S; Ray S; Bhakat KK
    Oncotarget; 2016 Nov; 7(46):75197-75209. PubMed ID: 27655688
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
    Trilles R; Beglov D; Chen Q; He H; Wireman R; Reed A; Chennamadhavuni S; Panek JS; Brown LE; Vajda S; Porco JA; Kelley MR; Georgiadis MM
    J Med Chem; 2019 Feb; 62(4):1971-1988. PubMed ID: 30653918
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone.
    Luo M; Kelley MR
    Anticancer Res; 2004; 24(4):2127-34. PubMed ID: 15330152
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition.
    Wang D; Luo M; Kelley MR
    Mol Cancer Ther; 2004 Jun; 3(6):679-86. PubMed ID: 15210853
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformational Rearrangements Regulating the DNA Repair Protein APE1.
    Komaniecka N; Porras M; Cairn L; Santas JA; Ferreiro N; Penedo JC; Bañuelos S
    Int J Mol Sci; 2022 Jul; 23(14):. PubMed ID: 35887361
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of 3-carbamoylbenzoic acid derivatives as inhibitors of human apurinic/apyrimidinic endonuclease 1 (APE1).
    Aiello F; Shabaik Y; Esqueda A; Sanchez TW; Grande F; Garofalo A; Neamati N
    ChemMedChem; 2012 Oct; 7(10):1825-39. PubMed ID: 22952012
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors.
    Zawahir Z; Dayam R; Deng J; Pereira C; Neamati N
    J Med Chem; 2009 Jan; 52(1):20-32. PubMed ID: 19072053
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.