BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

482 related articles for article (PubMed ID: 25866135)

  • 1. Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain.
    Pearce MMP; Spartz EJ; Hong W; Luo L; Kopito RR
    Nat Commun; 2015 Apr; 6():6768. PubMed ID: 25866135
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses.
    Donnelly KM; DeLorenzo OR; Zaya AD; Pisano GE; Thu WM; Luo L; Kopito RR; Panning Pearce MM
    Elife; 2020 May; 9():. PubMed ID: 32463364
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
    Onur TS; Laitman A; Zhao H; Keyho R; Kim H; Wang J; Mair M; Wang H; Li L; Perez A; de Haro M; Wan YW; Allen G; Lu B; Al-Ramahi I; Liu Z; Botas J
    Elife; 2021 Apr; 10():. PubMed ID: 33871358
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Visualization of prion-like transfer in Huntington's disease models.
    Jansen AH; Batenburg KL; Pecho-Vrieseling E; Reits EA
    Biochim Biophys Acta Mol Basis Dis; 2017 Mar; 1863(3):793-800. PubMed ID: 28040507
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insulin-like Signaling Promotes Glial Phagocytic Clearance of Degenerating Axons through Regulation of Draper.
    Musashe DT; Purice MD; Speese SD; Doherty J; Logan MA
    Cell Rep; 2016 Aug; 16(7):1838-50. PubMed ID: 27498858
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased energy metabolism rescues glia-induced pathology in a Drosophila model of Huntington's disease.
    Besson MT; Dupont P; Fridell YW; Liévens JC
    Hum Mol Genet; 2010 Sep; 19(17):3372-82. PubMed ID: 20566711
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model.
    Zhang S; Feany MB; Saraswati S; Littleton JT; Perrimon N
    Dis Model Mech; 2009; 2(5-6):247-66. PubMed ID: 19380309
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glial Phagocytic Receptors Promote Neuronal Loss in Adult Drosophila Brain.
    Hakim-Mishnaevski K; Flint-Brodsly N; Shklyar B; Levy-Adam F; Kurant E
    Cell Rep; 2019 Nov; 29(6):1438-1448.e3. PubMed ID: 31693886
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors.
    Banerjee M; Datta M; Bhattacharyya NP
    Int J Biochem Cell Biol; 2017 Jan; 82():1-9. PubMed ID: 27840155
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impairment of the glial phagolysosomal system drives prion-like propagation in a
    Davis GH; Zaya A; Pearce MMP
    bioRxiv; 2024 Feb; ():. PubMed ID: 38370619
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reducing canonical Wingless/Wnt signaling pathway confers protection against mutant Huntingtin toxicity in Drosophila.
    Dupont P; Besson MT; Devaux J; Liévens JC
    Neurobiol Dis; 2012 Aug; 47(2):237-47. PubMed ID: 22531500
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modeling Huntington disease in Drosophila: Insights into axonal transport defects and modifiers of toxicity.
    Krench M; Littleton JT
    Fly (Austin); 2013; 7(4):229-36. PubMed ID: 24022020
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila.
    Zhang S; Binari R; Zhou R; Perrimon N
    Genetics; 2010 Apr; 184(4):1165-79. PubMed ID: 20100940
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity.
    Zhu Y; Li C; Tao X; Brazill JM; Park J; Diaz-Perez Z; Zhai RG
    Proc Natl Acad Sci U S A; 2019 Sep; 116(38):19165-19175. PubMed ID: 31484760
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Negative regulation of glial engulfment activity by Draper terminates glial responses to axon injury.
    Logan MA; Hackett R; Doherty J; Sheehan A; Speese SD; Freeman MR
    Nat Neurosci; 2012 Mar; 15(5):722-30. PubMed ID: 22426252
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Draper-mediated JNK signaling is required for glial phagocytosis of apoptotic neurons during Drosophila metamorphosis.
    Hilu-Dadia R; Hakim-Mishnaevski K; Levy-Adam F; Kurant E
    Glia; 2018 Jul; 66(7):1520-1532. PubMed ID: 29520845
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Defective Phagocytic Corpse Processing Results in Neurodegeneration and Can Be Rescued by TORC1 Activation.
    Etchegaray JI; Elguero EJ; Tran JA; Sinatra V; Feany MB; McCall K
    J Neurosci; 2016 Mar; 36(11):3170-83. PubMed ID: 26985028
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Delayed glial clearance of degenerating axons in aged Drosophila is due to reduced PI3K/Draper activity.
    Purice MD; Speese SD; Logan MA
    Nat Commun; 2016 Sep; 7():12871. PubMed ID: 27647497
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The c-Jun kinase signaling cascade promotes glial engulfment activity through activation of draper and phagocytic function.
    Macdonald JM; Doherty J; Hackett R; Freeman MR
    Cell Death Differ; 2013 Sep; 20(9):1140-8. PubMed ID: 23618811
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart.
    Melkani GC; Trujillo AS; Ramos R; Bodmer R; Bernstein SI; Ocorr K
    PLoS Genet; 2013; 9(12):e1004024. PubMed ID: 24367279
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.