BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 25873482)

  • 1. Quantitative Proteomics of Human Fibroblasts with I1061T Mutation in Niemann-Pick C1 (NPC1) Protein Provides Insights into the Disease Pathogenesis.
    Rauniyar N; Subramanian K; Lavallée-Adam M; Martínez-Bartolomé S; Balch WE; Yates JR
    Mol Cell Proteomics; 2015 Jul; 14(7):1734-49. PubMed ID: 25873482
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease.
    Subramanian K; Rauniyar N; Lavalleé-Adam M; Yates JR; Balch WE
    Mol Cell Proteomics; 2017 Nov; 16(11):1938-1957. PubMed ID: 28860124
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding.
    Gelsthorpe ME; Baumann N; Millard E; Gale SE; Langmade SJ; Schaffer JE; Ory DS
    J Biol Chem; 2008 Mar; 283(13):8229-36. PubMed ID: 18216017
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts.
    Pipalia NH; Cosner CC; Huang A; Chatterjee A; Bourbon P; Farley N; Helquist P; Wiest O; Maxfield FR
    Proc Natl Acad Sci U S A; 2011 Apr; 108(14):5620-5. PubMed ID: 21436030
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele.
    Praggastis M; Tortelli B; Zhang J; Fujiwara H; Sidhu R; Chacko A; Chen Z; Chung C; Lieberman AP; Sikora J; Davidson C; Walkley SU; Pipalia NH; Maxfield FR; Schaffer JE; Ory DS
    J Neurosci; 2015 May; 35(21):8091-106. PubMed ID: 26019327
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells.
    Pipalia NH; Subramanian K; Mao S; Ralph H; Hutt DM; Scott SM; Balch WE; Maxfield FR
    J Lipid Res; 2017 Apr; 58(4):695-708. PubMed ID: 28193631
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Primary cilium alterations and expression changes of Patched1 proteins in niemann-pick type C disease.
    Formichi P; Battisti C; De Santi MM; Guazzo R; Tripodi SA; Radi E; Rossi B; Tarquini E; Federico A
    J Cell Physiol; 2018 Jan; 233(1):663-672. PubMed ID: 28332184
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ryanodine receptor antagonists adapt NPC1 proteostasis to ameliorate lipid storage in Niemann-Pick type C disease fibroblasts.
    Yu T; Chung C; Shen D; Xu H; Lieberman AP
    Hum Mol Genet; 2012 Jul; 21(14):3205-14. PubMed ID: 22505584
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The proteasome inhibitor bortezomib reduced cholesterol accumulation in fibroblasts from Niemann-Pick type C patients carrying missense mutations.
    Macías-Vidal J; Girós M; Guerrero M; Gascón P; Serratosa J; Bachs O; Coll MJ
    FEBS J; 2014 Oct; 281(19):4450-66. PubMed ID: 25131710
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationships of oxysterol-derived pharmacological chaperones for Niemann-Pick type C1 protein.
    Ohgane K; Karaki F; Noguchi-Yachide T; Dodo K; Hashimoto Y
    Bioorg Med Chem Lett; 2014 Aug; 24(15):3480-5. PubMed ID: 24928400
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1.
    Sun X; Marks DL; Park WD; Wheatley CL; Puri V; O'Brien JF; Kraft DL; Lundquist PA; Patterson MC; Pagano RE; Snow K
    Am J Hum Genet; 2001 Jun; 68(6):1361-72. PubMed ID: 11349231
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rescue of an in vitro neuron phenotype identified in Niemann-Pick disease, type C1 induced pluripotent stem cell-derived neurons by modulating the WNT pathway and calcium signaling.
    Efthymiou AG; Steiner J; Pavan WJ; Wincovitch S; Larson DM; Porter FD; Rao MS; Malik N
    Stem Cells Transl Med; 2015 Mar; 4(3):230-8. PubMed ID: 25637190
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High-content screen for modifiers of Niemann-Pick type C disease in patient cells.
    Pugach EK; Feltes M; Kaufman RJ; Ory DS; Bang AG
    Hum Mol Genet; 2018 Jun; 27(12):2101-2112. PubMed ID: 29659804
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling.
    Reddy JV; Ganley IG; Pfeffer SR
    PLoS One; 2006 Dec; 1(1):e19. PubMed ID: 17183645
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different Trafficking Phenotypes of Niemann-Pick C1 Gene Mutations Correlate with Various Alterations in Lipid Storage, Membrane Composition and Miglustat Amenability.
    Brogden G; Shammas H; Walters F; Maalouf K; Das AM; Naim HY; Rizk S
    Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32204338
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Altered vitamin E status in Niemann-Pick type C disease.
    Ulatowski L; Parker R; Davidson C; Yanjanin N; Kelley TJ; Corey D; Atkinson J; Porter F; Arai H; Walkley SU; Manor D
    J Lipid Res; 2011 Jul; 52(7):1400-10. PubMed ID: 21550990
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
    Boadu E; Nelson RC; Francis GA
    Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of mammalian terget of rapamycin kinase and glycogen synthase kinase-3β accompanies abnormal accumulation of cholesterol in fibroblasts from Niemann-Pick type C patients.
    Wos M; Komiażyk M; Pikula S; Tylki-Szymanska A; Bandorowicz-Pikula J
    J Cell Biochem; 2019 Apr; 120(4):6580-6588. PubMed ID: 30390318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quantitative, Label-Free Proteomics in the Symptomatic Niemann-Pick, Type C1 Mouse Model Using Standard Flow Liquid Chromatography and Thermal Focusing Electrospray Ionization.
    Pergande MR; Nguyen TTA; Haney-Ball C; Davidson CD; Cologna SM
    Proteomics; 2019 May; 19(9):e1800432. PubMed ID: 30888112
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial dysfunction in fibroblasts derived from patients with Niemann-Pick type C disease.
    Woś M; Szczepanowska J; Pikuła S; Tylki-Szymańska A; Zabłocki K; Bandorowicz-Pikuła J
    Arch Biochem Biophys; 2016 Mar; 593():50-9. PubMed ID: 26869201
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.