268 related articles for article (PubMed ID: 25874336)
1. Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation.
Varano F; Catarzi D; Squarcialupi L; Betti M; Vincenzi F; Ravani A; Varani K; Dal Ben D; Thomas A; Volpini R; Colotta V
Eur J Med Chem; 2015; 96():105-21. PubMed ID: 25874336
[TBL] [Abstract][Full Text] [Related]
2. Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor.
Squarcialupi L; Catarzi D; Varano F; Betti M; Falsini M; Vincenzi F; Ravani A; Ciancetta A; Varani K; Moro S; Colotta V
Eur J Med Chem; 2016 Jan; 108():117-133. PubMed ID: 26638043
[TBL] [Abstract][Full Text] [Related]
3. A facile and novel synthesis of N(2)-, C(6)-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists.
Venkatesan G; Paira P; Cheong SL; Federico S; Klotz KN; Spalluto G; Pastorin G
Eur J Med Chem; 2015 Mar; 92():784-98. PubMed ID: 25633494
[TBL] [Abstract][Full Text] [Related]
4. 2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives as new potent and selective human A3 adenosine receptor antagonists. Molecular modeling studies and pharmacological evaluation.
Squarcialupi L; Colotta V; Catarzi D; Varano F; Filacchioni G; Varani K; Corciulo C; Vincenzi F; Borea PA; Ghelardini C; Di Cesare Mannelli L; Ciancetta A; Moro S
J Med Chem; 2013 Mar; 56(6):2256-69. PubMed ID: 23427825
[TBL] [Abstract][Full Text] [Related]
5. New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Baraldi PG; Preti D; Zaid AN; Saponaro G; Tabrizi MA; Baraldi S; Romagnoli R; Moorman AR; Varani K; Cosconati S; Di Maro S; Marinelli L; Novellino E; Borea PA
J Med Chem; 2011 Jul; 54(14):5205-20. PubMed ID: 21675777
[TBL] [Abstract][Full Text] [Related]
6. Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity.
Varano F; Catarzi D; Falsini M; Dal Ben D; Buccioni M; Marucci G; Volpini R; Colotta V
Bioorg Med Chem Lett; 2019 Feb; 29(4):563-569. PubMed ID: 30638876
[TBL] [Abstract][Full Text] [Related]
7. 1,2,4-triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A₃ receptor antagonists. Synthesis, structure-affinity relationships and molecular modeling studies.
Catarzi D; Varano F; Poli D; Squarcialupi L; Betti M; Trincavelli L; Martini C; Dal Ben D; Thomas A; Volpini R; Colotta V
Bioorg Med Chem; 2015 Jan; 23(1):9-21. PubMed ID: 25497490
[TBL] [Abstract][Full Text] [Related]
8. Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A
Poli D; Falsini M; Varano F; Betti M; Varani K; Vincenzi F; Pugliese AM; Pedata F; Dal Ben D; Thomas A; Palchetti I; Bettazzi F; Catarzi D; Colotta V
Eur J Med Chem; 2017 Jan; 125():611-628. PubMed ID: 27721147
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of novel pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives: potent and selective adenosine A3 receptor antagonists.
Banda V; Chandrasekaran B; Köse M; Vielmuth C; Müller CE; Chavva K; Gautham SK; Pillalamarri S; Mylavaram R; Akkinepally R; Pamulaparthy S; Banda N
Arch Pharm (Weinheim); 2013 Oct; 346(10):699-707. PubMed ID: 23996524
[TBL] [Abstract][Full Text] [Related]
10. Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists.
Yaziji V; Rodríguez D; Gutiérrez-de-Terán H; Coelho A; Caamaño O; García-Mera X; Brea J; Loza MI; Cadavid MI; Sotelo E
J Med Chem; 2011 Jan; 54(2):457-71. PubMed ID: 21186795
[TBL] [Abstract][Full Text] [Related]
11. 7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: structural investigations at the 5-position to target human A₁ and A(2A) adenosine receptors. Molecular modeling and pharmacological studies.
Squarcialupi L; Colotta V; Catarzi D; Varano F; Betti M; Varani K; Vincenzi F; Borea PA; Porta N; Ciancetta A; Moro S
Eur J Med Chem; 2014 Sep; 84():614-27. PubMed ID: 25063944
[TBL] [Abstract][Full Text] [Related]
12. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
Pastorin G; Da Ros T; Spalluto G; Deflorian F; Moro S; Cacciari B; Baraldi PG; Gessi S; Varani K; Borea PA
J Med Chem; 2003 Sep; 46(20):4287-96. PubMed ID: 13678407
[TBL] [Abstract][Full Text] [Related]
13. Structure-activity relationship studies and pharmacological characterization of N
Varano F; Catarzi D; Vincenzi F; Falsini M; Pasquini S; Borea PA; Colotta V; Varani K
Eur J Med Chem; 2018 Jul; 155():552-561. PubMed ID: 29909340
[TBL] [Abstract][Full Text] [Related]
14. Scaffold decoration at positions 5 and 8 of 1,2,4-triazolo[1,5-c]pyrimidines to explore the antagonist profiling on adenosine receptors: a preliminary structure-activity relationship study.
Federico S; Ciancetta A; Porta N; Redenti S; Pastorin G; Cacciari B; Klotz KN; Moro S; Spalluto G
J Med Chem; 2014 Jul; 57(14):6210-25. PubMed ID: 24972108
[TBL] [Abstract][Full Text] [Related]
15. QSAR of adenosine receptor antagonists: Exploring physicochemical requirements for binding of pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives with human adenosine A(3) receptor subtype.
Pran Kishore D; Balakumar C; Raghuram Rao A; Roy PP; Roy K
Bioorg Med Chem Lett; 2011 Jan; 21(2):818-23. PubMed ID: 21163647
[TBL] [Abstract][Full Text] [Related]
16. [1,2,4]Triazolo[1,5-c]pyrimidines as adenosine receptor antagonists: Modifications at the 8 position to reach selectivity towards A
Federico S; Margiotta E; Salmaso V; Pastorin G; Kachler S; Klotz KN; Moro S; Spalluto G
Eur J Med Chem; 2018 Sep; 157():837-851. PubMed ID: 30144700
[TBL] [Abstract][Full Text] [Related]
17. The identification of the 2-phenylphthalazin-1(2H)-one scaffold as a new decorable core skeleton for the design of potent and selective human A3 adenosine receptor antagonists.
Poli D; Catarzi D; Colotta V; Varano F; Filacchioni G; Daniele S; Trincavelli L; Martini C; Paoletta S; Moro S
J Med Chem; 2011 Apr; 54(7):2102-13. PubMed ID: 21401121
[TBL] [Abstract][Full Text] [Related]
18. The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A
Squarcialupi L; Betti M; Catarzi D; Varano F; Falsini M; Ravani A; Pasquini S; Vincenzi F; Salmaso V; Sturlese M; Varani K; Moro S; Colotta V
J Enzyme Inhib Med Chem; 2017 Dec; 32(1):248-263. PubMed ID: 28114825
[TBL] [Abstract][Full Text] [Related]
19. Substituted 4-phenylthiazoles: Development of potent and selective A
Abdelrahman A; Yerande SG; Namasivayam V; Klapschinski TA; Alnouri MW; El-Tayeb A; Müller CE
Eur J Med Chem; 2020 Jan; 186():111879. PubMed ID: 31780082
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological studies of a new series of 5-heteroarylcarbamoylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as human A3 adenosine receptor antagonists. Influence of the heteroaryl substituent on binding affinity and molecular modeling investigations.
Pastorin G; Da Ros T; Bolcato C; Montopoli C; Moro S; Cacciari B; Baraldi PG; Varani K; Borea PA; Spalluto G
J Med Chem; 2006 Mar; 49(5):1720-9. PubMed ID: 16509587
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]