These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 25874340)

  • 21. Heme oxygenase inhibition by 2-oxy-substituted 1-azolyl-4-phenylbutanes: effect of variation of the azole moiety. X-ray crystal structure of human heme oxygenase-1 in complex with 4-phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone.
    Roman G; Rahman MN; Vukomanovic D; Jia Z; Nakatsu K; Szarek WA
    Chem Biol Drug Des; 2010 Jan; 75(1):68-90. PubMed ID: 19954435
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents.
    Abdelgawad MA; Bakr RB; Omar HA
    Bioorg Chem; 2017 Oct; 74():82-90. PubMed ID: 28772160
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region.
    Floresta G; Fallica AN; Romeo G; Sorrenti V; Salerno L; Rescifina A; Pittalà V
    Bioorg Chem; 2020 Nov; 104():104310. PubMed ID: 33010625
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structure-Activity Relationships of 1,2-Disubstituted Benzimidazoles: Selective Inhibition of Heme Oxygenase-2 Activity.
    Kong X; Vukomanovic D; Nakatsu K; Szarek WA
    ChemMedChem; 2015 Aug; 10(8):1435-41. PubMed ID: 26083133
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Upregulation of both heme oxygenase-1 and ATPase inhibitory factor 1 renders tumoricidal activity by synthetic flavonoids via depleting cellular ATP.
    Lee PJ; Shin I; Seo SY; Kim H; Kim HP
    Bioorg Med Chem Lett; 2014 Oct; 24(20):4845-9. PubMed ID: 25223958
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibitors of the heme oxygenase - carbon monoxide system: on the doorstep of the clinic?
    Kinobe RT; Dercho RA; Nakatsu K
    Can J Physiol Pharmacol; 2008 Sep; 86(9):577-99. PubMed ID: 18758507
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors.
    Salerno L; Amata E; Romeo G; Marrazzo A; Prezzavento O; Floresta G; Sorrenti V; Barbagallo I; Rescifina A; Pittalà V
    Eur J Med Chem; 2018 Mar; 148():54-62. PubMed ID: 29454190
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Growing the molecular architecture of imidazole-like ligands in HO-1 complexes.
    Floresta G; Fallica AN; Salerno L; Sorrenti V; Pittalà V; Rescifina A
    Bioorg Chem; 2021 Dec; 117():105428. PubMed ID: 34710668
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors.
    Intagliata S; Salerno L; Ciaffaglione V; Leonardi C; Fallica AN; Carota G; Amata E; Marrazzo A; Pittalà V; Romeo G
    Eur J Med Chem; 2019 Dec; 183():111703. PubMed ID: 31550661
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Statin-induced heme oxygenase-1 increases NF-kappaB activation and oxygen radical production in cultured neuronal cells exposed to lipopolysaccharide.
    Hsieh CH; Jeng SF; Hsieh MW; Chen YC; Rau CS; Lu TH; Chen SS
    Toxicol Sci; 2008 Mar; 102(1):150-9. PubMed ID: 18073186
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Interaction of heme with nitroxyl or nitric oxide amplifies heme oxygenase-1 induction: involvement of the transcription factor Nrf2.
    Naughton P; Hoque M; Green CJ; Foresti R; Motterlini R
    Cell Mol Biol (Noisy-le-grand); 2002 Dec; 48(8):885-94. PubMed ID: 12699247
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Evaluation of imidazole-based compounds as heme oxygenase-1 inhibitors.
    Sorrenti V; Guccione S; Di Giacomo C; Modica MN; Pittalà V; Acquaviva R; Basile L; Pappalardo M; Salerno L
    Chem Biol Drug Des; 2012 Dec; 80(6):876-86. PubMed ID: 22882835
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design, synthesis and biological evaluation of novel hybrid compounds of imidazole scaffold-based 2-benzylbenzofuran as potent anticancer agents.
    Wang XQ; Liu LX; Li Y; Sun CJ; Chen W; Li L; Zhang HB; Yang XD
    Eur J Med Chem; 2013 Apr; 62():111-21. PubMed ID: 23353748
    [TBL] [Abstract][Full Text] [Related]  

  • 34. In vitro inhibition of heme oxygenase isoenzymes by metalloporphyrins.
    Wong RJ; Vreman HJ; Schulz S; Kalish FS; Pierce NW; Stevenson DK
    J Perinatol; 2011 Apr; 31 Suppl 1():S35-41. PubMed ID: 21448202
    [TBL] [Abstract][Full Text] [Related]  

  • 35. NHC gold halide complexes derived from 4,5-diarylimidazoles: synthesis, structural analysis, and pharmacological investigations as potential antitumor agents.
    Liu W; Bensdorf K; Proetto M; Abram U; Hagenbach A; Gust R
    J Med Chem; 2011 Dec; 54(24):8605-15. PubMed ID: 22091836
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines.
    Ding Y; Zhang YZ; Furuyama K; Ogawa K; Igarashi K; Shibahara S
    FEBS J; 2006 Dec; 273(23):5333-46. PubMed ID: 17064313
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis and biological evaluation of benzo[d]imidazole derivatives as potential anti-cancer agents.
    Alkahtani HM; Abbas AY; Wang S
    Bioorg Med Chem Lett; 2012 Feb; 22(3):1317-21. PubMed ID: 22225635
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1.
    Zhang W; Contag PR; Hardy J; Zhao H; Vreman HJ; Hajdena-Dawson M; Wong RJ; Stevenson DK; Contag CH
    J Mol Med (Berl); 2002 Oct; 80(10):655-64. PubMed ID: 12395150
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase.
    Hill M; Pereira V; Chauveau C; Zagani R; Remy S; Tesson L; Mazal D; Ubillos L; Brion R; Asghar K; Mashreghi MF; Kotsch K; Moffett J; Doebis C; Seifert M; Boczkowski J; Osinaga E; Anegon I
    FASEB J; 2005 Dec; 19(14):1957-68. PubMed ID: 16319139
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity.
    Romeo G; Ciaffaglione V; Amata E; Dichiara M; Calabrese L; Vanella L; Sorrenti V; Grosso S; D'Amico AG; D'Agata V; Intagliata S; Salerno L
    Molecules; 2021 Jun; 26(13):. PubMed ID: 34202711
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.