These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

424 related articles for article (PubMed ID: 25880554)

  • 21. Mechanistic Target of Rapamycin Complex 1 (mTORC1) and mTORC2 as Key Signaling Intermediates in Mesenchymal Cell Activation.
    Walker NM; Belloli EA; Stuckey L; Chan KM; Lin J; Lynch W; Chang A; Mazzoni SM; Fingar DC; Lama VN
    J Biol Chem; 2016 Mar; 291(12):6262-71. PubMed ID: 26755732
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
    Feldman ME; Apsel B; Uotila A; Loewith R; Knight ZA; Ruggero D; Shokat KM
    PLoS Biol; 2009 Feb; 7(2):e38. PubMed ID: 19209957
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
    Wang S; Amato KR; Song W; Youngblood V; Lee K; Boothby M; Brantley-Sieders DM; Chen J
    Mol Cell Biol; 2015 Apr; 35(7):1299-313. PubMed ID: 25582201
    [TBL] [Abstract][Full Text] [Related]  

  • 24. IKK interacts with rictor and regulates mTORC2.
    Xu Y; Lai E; Liu J; Lin J; Yang C; Jia C; Li Y; Bai X; Li M
    Cell Signal; 2013 Nov; 25(11):2239-45. PubMed ID: 23872070
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Compensation of the AKT signaling by ERK signaling in transgenic mice hearts overexpressing TRIM72.
    Ham YM; Mahoney SJ
    Exp Cell Res; 2013 Jun; 319(10):1451-62. PubMed ID: 23567182
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W.
    Jeon YH; Park YH; Kwon JH; Lee JH; Kim IY
    Biochim Biophys Acta; 2013 Oct; 1833(10):2135-42. PubMed ID: 23680186
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.
    Shende P; Xu L; Morandi C; Pentassuglia L; Heim P; Lebboukh S; Berthonneche C; Pedrazzini T; Kaufmann BA; Hall MN; Rüegg MA; Brink M
    Cardiovasc Res; 2016 Jan; 109(1):103-14. PubMed ID: 26598511
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Rapamycin regulates Akt and ERK phosphorylation through mTORC1 and mTORC2 signaling pathways.
    Chen XG; Liu F; Song XF; Wang ZH; Dong ZQ; Hu ZQ; Lan RZ; Guan W; Zhou TG; Xu XM; Lei H; Ye ZQ; Peng EJ; Du LH; Zhuang QY
    Mol Carcinog; 2010 Jun; 49(6):603-10. PubMed ID: 20512842
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.
    Lamming DW; Mihaylova MM; Katajisto P; Baar EL; Yilmaz OH; Hutchins A; Gultekin Y; Gaither R; Sabatini DM
    Aging Cell; 2014 Oct; 13(5):911-7. PubMed ID: 25059582
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.
    Shu L; Houghton PJ
    Mol Cell Biol; 2009 Sep; 29(17):4691-700. PubMed ID: 19564418
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Reduced menin expression impairs rapamycin effects as evidenced by an increase in mTORC2 signaling and cell migration.
    Razmara M; Monazzam A; Skogseid B
    Cell Commun Signal; 2018 Oct; 16(1):64. PubMed ID: 30285764
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Rapamycin regulates the balance between cardiomyocyte apoptosis and autophagy in chronic heart failure by inhibiting mTOR signaling.
    Gao G; Chen W; Yan M; Liu J; Luo H; Wang C; Yang P
    Int J Mol Med; 2020 Jan; 45(1):195-209. PubMed ID: 31746373
    [TBL] [Abstract][Full Text] [Related]  

  • 33. mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
    Fan W; Cheng K; Qin X; Narsinh KH; Wang S; Hu S; Wang Y; Chen Y; Wu JC; Xiong L; Cao F
    Stem Cells; 2013 Jan; 31(1):203-14. PubMed ID: 23081858
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers.
    Morrison Joly M; Hicks DJ; Jones B; Sanchez V; Estrada MV; Young C; Williams M; Rexer BN; Sarbassov dos D; Muller WJ; Brantley-Sieders D; Cook RS
    Cancer Res; 2016 Aug; 76(16):4752-64. PubMed ID: 27197158
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation.
    Dalle Pezze P; Sonntag AG; Thien A; Prentzell MT; Gödel M; Fischer S; Neumann-Haefelin E; Huber TB; Baumeister R; Shanley DP; Thedieck K
    Sci Signal; 2012 Mar; 5(217):ra25. PubMed ID: 22457331
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Gβγ interacts with mTOR and promotes its activation.
    Robles-Molina E; Dionisio-Vicuña M; Guzmán-Hernández ML; Reyes-Cruz G; Vázquez-Prado J
    Biochem Biophys Res Commun; 2014 Feb; 444(2):218-23. PubMed ID: 24462769
    [TBL] [Abstract][Full Text] [Related]  

  • 37. High prevalence of mTOR complex activity can be targeted using Torin2 in papillary thyroid carcinoma.
    Ahmed M; Hussain AR; Bavi P; Ahmed SO; Al Sobhi SS; Al-Dayel F; Uddin S; Al-Kuraya KS
    Carcinogenesis; 2014 Jul; 35(7):1564-72. PubMed ID: 24583924
    [TBL] [Abstract][Full Text] [Related]  

  • 38. mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.
    Kim SJ; DeStefano MA; Oh WJ; Wu CC; Vega-Cotto NM; Finlan M; Liu D; Su B; Jacinto E
    Mol Cell; 2012 Dec; 48(6):875-87. PubMed ID: 23142081
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Pharmacological Inhibition of mTOR Kinase Reverses Right Ventricle Remodeling and Improves Right Ventricle Structure and Function in Rats.
    Pena A; Kobir A; Goncharov D; Goda A; Kudryashova TV; Ray A; Vanderpool R; Baust J; Chang B; Mora AL; Gorcsan J; Goncharova EA
    Am J Respir Cell Mol Biol; 2017 Nov; 57(5):615-625. PubMed ID: 28679058
    [TBL] [Abstract][Full Text] [Related]  

  • 40. mTOR has a developmental stage-specific role in mitochondrial fitness independent of conventional mTORC1 and mTORC2 and the kinase activity.
    Kalim KW; Zhang S; Chen X; Li Y; Yang JQ; Zheng Y; Guo F
    PLoS One; 2017; 12(8):e0183266. PubMed ID: 28813526
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.