BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

488 related articles for article (PubMed ID: 25881142)

  • 1. Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies.
    Chiasserini D; Paciotti S; Eusebi P; Persichetti E; Tasegian A; Kurzawa-Akanbi M; Chinnery PF; Morris CM; Calabresi P; Parnetti L; Beccari T
    Mol Neurodegener; 2015 Mar; 10():15. PubMed ID: 25881142
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson's Disease and Dementia with Lewy Bodies.
    Moors TE; Paciotti S; Ingrassia A; Quadri M; Breedveld G; Tasegian A; Chiasserini D; Eusebi P; Duran-Pacheco G; Kremer T; Calabresi P; Bonifati V; Parnetti L; Beccari T; van de Berg WDJ
    Mol Neurobiol; 2019 Feb; 56(2):1344-1355. PubMed ID: 29948939
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains.
    Gegg ME; Burke D; Heales SJ; Cooper JM; Hardy J; Wood NW; Schapira AH
    Ann Neurol; 2012 Sep; 72(3):455-63. PubMed ID: 23034917
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Path mediation analysis reveals GBA impacts Lewy body disease status by increasing α-synuclein levels.
    Gündner AL; Duran-Pacheco G; Zimmermann S; Ruf I; Moors T; Baumann K; Jagasia R; van de Berg WDJ; Kremer T
    Neurobiol Dis; 2019 Jan; 121():205-213. PubMed ID: 30236861
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease.
    Huebecker M; Moloney EB; van der Spoel AC; Priestman DA; Isacson O; Hallett PJ; Platt FM
    Mol Neurodegener; 2019 Nov; 14(1):40. PubMed ID: 31703585
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.
    Mazzulli JR; Zunke F; Tsunemi T; Toker NJ; Jeon S; Burbulla LF; Patnaik S; Sidransky E; Marugan JJ; Sue CM; Krainc D
    J Neurosci; 2016 Jul; 36(29):7693-706. PubMed ID: 27445146
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells.
    Deen MC; Zhu Y; Gros C; Na N; Gilormini PA; Shen DL; Bhosale S; Anastasi N; Wang R; Shan X; Harde E; Jagasia R; Lynn FC; Vocadlo DJ
    Proc Natl Acad Sci U S A; 2022 Jul; 119(29):e2200553119. PubMed ID: 35858317
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucocerebrosidase and Parkinson disease: Recent advances.
    Schapira AH
    Mol Cell Neurosci; 2015 May; 66(Pt A):37-42. PubMed ID: 25802027
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [GBA mutations and Parkinson's disease].
    Wang DX; Xie JX; Song N
    Sheng Li Xue Bao; 2018 Jun; 70(3):294-300. PubMed ID: 29926071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons.
    Rocha EM; Smith GA; Park E; Cao H; Brown E; Hayes MA; Beagan J; McLean JR; Izen SC; Perez-Torres E; Hallett PJ; Isacson O
    Neurobiol Dis; 2015 Oct; 82():495-503. PubMed ID: 26392287
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucocerebrosidase dysfunction in neurodegenerative disease.
    Brooker SM; Krainc D
    Essays Biochem; 2021 Dec; 65(7):873-883. PubMed ID: 34528667
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export.
    Martin S; Smolders S; Van den Haute C; Heeman B; van Veen S; Crosiers D; Beletchi I; Verstraeten A; Gossye H; Gelders G; Pals P; Hamouda NN; Engelborghs S; Martin JJ; Eggermont J; De Deyn PP; Cras P; Baekelandt V; Vangheluwe P; Van Broeckhoven C;
    Acta Neuropathol; 2020 Jun; 139(6):1001-1024. PubMed ID: 32172343
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice.
    Rocha EM; Smith GA; Park E; Cao H; Graham AR; Brown E; McLean JR; Hayes MA; Beagan J; Izen SC; Perez-Torres E; Hallett PJ; Isacson O
    Antioxid Redox Signal; 2015 Aug; 23(6):550-64. PubMed ID: 26094487
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of Strategies for Measuring Lysosomal Glucocerebrosidase Activity.
    Ysselstein D; Young TJ; Nguyen M; Padmanabhan S; Hirst WD; Dzamko N; Krainc D
    Mov Disord; 2021 Dec; 36(12):2719-2730. PubMed ID: 34613624
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of β-glucocerebrosidase increases α-synuclein secretion and exosome release in mouse models of Parkinson's disease.
    Papadopoulos VE; Nikolopoulou G; Antoniadou I; Karachaliou A; Arianoglou G; Emmanouilidou E; Sardi SP; Stefanis L; Vekrellis K
    Hum Mol Genet; 2018 May; 27(10):1696-1710. PubMed ID: 29547959
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Parkinson's disease: acid-glucocerebrosidase activity and alpha-synuclein clearance.
    Blanz J; Saftig P
    J Neurochem; 2016 Oct; 139 Suppl 1():198-215. PubMed ID: 26860955
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lysosomal enzyme activities as possible CSF biomarkers of synucleinopathies.
    Paciotti S; Gatticchi L; Beccari T; Parnetti L
    Clin Chim Acta; 2019 Aug; 495():13-24. PubMed ID: 30922855
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lysosomal functions and dysfunctions: Molecular and cellular mechanisms underlying Gaucher disease and its association with Parkinson disease.
    Horowitz M; Braunstein H; Zimran A; Revel-Vilk S; Goker-Alpan O
    Adv Drug Deliv Rev; 2022 Aug; 187():114402. PubMed ID: 35764179
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Measurement of GCase Activity in Cultured Cells.
    Shojima Y; Ogata J; Tsunemi T; Imai Y; Hattori N
    Methods Mol Biol; 2021; 2322():47-52. PubMed ID: 34043191
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fibroblasts from idiopathic Parkinson's disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2.
    Thomas R; Moloney EB; Macbain ZK; Hallett PJ; Isacson O
    Mol Brain; 2021 Jan; 14(1):16. PubMed ID: 33468204
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.