239 related articles for article (PubMed ID: 25881233)
1. Dynamic modulation of thymidylate synthase gene expression and fluorouracil sensitivity in human colorectal cancer cells.
Wakasa K; Kawabata R; Nakao S; Hattori H; Taguchi K; Uchida J; Yamanaka T; Maehara Y; Fukushima M; Oda S
PLoS One; 2015; 10(4):e0123076. PubMed ID: 25881233
[TBL] [Abstract][Full Text] [Related]
2. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
Nita ME; Tominaga O; Nagawa H; Tsuruo T; Muto T
Hepatogastroenterology; 1998; 45(24):2117-22. PubMed ID: 9951876
[TBL] [Abstract][Full Text] [Related]
3. Combined therapy with a thymidylate synthase-inhibiting vector and S-1 has effective antitumor activity against 5-FU-resistant tumors.
Kadota K; Huang CL; Liu D; Yokomise H; Haba R; Wada H
Int J Oncol; 2011 Feb; 38(2):355-63. PubMed ID: 21174056
[TBL] [Abstract][Full Text] [Related]
4. The transfection of thymidylate synthase antisense suppresses oncogenic properties of a human colon cancer cell line and augments the antitumor effect of fluorouracil.
Matsuoka K; Tsukuda K; Suda M; Kobayashi K; Ota T; Okita A; Watanabe K; Suzuki E; Murakami M; Doihara H; Shimizu N
Int J Oncol; 2004 Jan; 24(1):217-22. PubMed ID: 14654960
[TBL] [Abstract][Full Text] [Related]
5. Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: three-gene expression model predicts clinical response.
Matsuyama R; Togo S; Shimizu D; Momiyama N; Ishikawa T; Ichikawa Y; Endo I; Kunisaki C; Suzuki H; Hayasizaki Y; Shimada H
Int J Cancer; 2006 Jul; 119(2):406-13. PubMed ID: 16477629
[TBL] [Abstract][Full Text] [Related]
6. Thymidylate synthase and microsatellite instability in colorectal cancer: implications for disease free survival, treatment response and survival with metastases.
Bendardaf R; Lamlum H; Ristamäki R; Korkeila E; Syrjänen K; Pyrhönen S
Acta Oncol; 2008; 47(6):1046-53. PubMed ID: 17943475
[TBL] [Abstract][Full Text] [Related]
7. MicroRNA-375-3p enhances chemosensitivity to 5-fluorouracil by targeting thymidylate synthase in colorectal cancer.
Xu F; Ye ML; Zhang YP; Li WJ; Li MT; Wang HZ; Qiu X; Xu Y; Yin JW; Hu Q; Wei WH; Chang Y; Liu L; Zhao Q
Cancer Sci; 2020 May; 111(5):1528-1541. PubMed ID: 32073706
[TBL] [Abstract][Full Text] [Related]
8. Lack of correlation between immunohistochemical expression of E2F-1, thymidylate synthase expression and clinical response to 5-fluorouracil in advanced colorectal cancer.
Belvedere O; Puglisi F; Di Loreto C; Cataldi P; Guglielmi A; Aschele C; Sobrero A
Ann Oncol; 2004 Jan; 15(1):55-8. PubMed ID: 14679120
[TBL] [Abstract][Full Text] [Related]
9. Overexpression of thymidylate synthase mediates desensitization for 5-fluorouracil of tumor cells.
Saga Y; Suzuki M; Mizukami H; Kohno T; Takei Y; Fukushima M; Ozawa K
Int J Cancer; 2003 Sep; 106(3):324-6. PubMed ID: 12845668
[TBL] [Abstract][Full Text] [Related]
10. Correlation between chemosensitivity and mRNA expression level of 5-fluorouracil-related metabolic enzymes during liver metastasis of colorectal cancer.
Okumura K; Shiomi H; Mekata E; Kaizuka M; Endo Y; Kurumi Y; Tani T
Oncol Rep; 2006 Apr; 15(4):875-82. PubMed ID: 16525674
[TBL] [Abstract][Full Text] [Related]
11. CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells.
Takagi K; Sowa Y; Cevik OM; Nakanishi R; Sakai T
Int J Oncol; 2008 May; 32(5):1105-10. PubMed ID: 18425338
[TBL] [Abstract][Full Text] [Related]
12. Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells.
Kawabata R; Oie S; Oka T; Takahashi M; Kanayama H; Itoh K
Int J Oncol; 2011 Mar; 38(3):665-76. PubMed ID: 21243325
[TBL] [Abstract][Full Text] [Related]
13. Thymidylate synthase levels: prognostic, predictive, or both?
Allegra C
J Clin Oncol; 2002 Apr; 20(7):1711-3. PubMed ID: 11919223
[No Abstract] [Full Text] [Related]
14. Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model.
Abu Lila AS; Moriyoshi N; Fukushima M; Huang CL; Wada H; Ishida T
Cancer Lett; 2017 Aug; 400():223-231. PubMed ID: 27838412
[TBL] [Abstract][Full Text] [Related]
15. Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase.
Milczarek M; Rossowska J; Klopotowska D; Stachowicz M; Kutner A; Wietrzyk J
J Steroid Biochem Mol Biol; 2019 Jun; 190():139-151. PubMed ID: 30923017
[TBL] [Abstract][Full Text] [Related]
16. Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents.
Yawata A; Kim SR; Miyajima A; Kubo T; Ishida S; Saito Y; Nakajima Y; Katori N; Matsumoto Y; Fukuoka M; Ohno Y; Ozawa S; Sawada J
Cancer Chemother Pharmacol; 2005 Nov; 56(5):465-72. PubMed ID: 15918040
[TBL] [Abstract][Full Text] [Related]
17. Single nucleotide polymorphism in the 5' tandem repeat sequences of thymidylate synthase gene predicts for response to fluorouracil-based chemotherapy in advanced colorectal cancer patients.
Marcuello E; Altés A; del Rio E; César A; Menoyo A; Baiget M
Int J Cancer; 2004 Dec; 112(5):733-7. PubMed ID: 15386371
[TBL] [Abstract][Full Text] [Related]
18. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.
Salonga D; Danenberg KD; Johnson M; Metzger R; Groshen S; Tsao-Wei DD; Lenz HJ; Leichman CG; Leichman L; Diasio RB; Danenberg PV
Clin Cancer Res; 2000 Apr; 6(4):1322-7. PubMed ID: 10778957
[TBL] [Abstract][Full Text] [Related]
19. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors.
Johnston PG; Lenz HJ; Leichman CG; Danenberg KD; Allegra CJ; Danenberg PV; Leichman L
Cancer Res; 1995 Apr; 55(7):1407-12. PubMed ID: 7882343
[TBL] [Abstract][Full Text] [Related]
20. Intratumoural thymidylate synthase and dihydropyrimidine dehydrogenase activities are good predictors of 5-fluorouracil sensitivity in colorectal cancer.
Ishibiki Y; Kitajima M; Sakamoto K; Tomiki Y; Sakamoto S; Kamano T
J Int Med Res; 2003; 31(3):181-7. PubMed ID: 12870370
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]