These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 25881233)

  • 1. Dynamic modulation of thymidylate synthase gene expression and fluorouracil sensitivity in human colorectal cancer cells.
    Wakasa K; Kawabata R; Nakao S; Hattori H; Taguchi K; Uchida J; Yamanaka T; Maehara Y; Fukushima M; Oda S
    PLoS One; 2015; 10(4):e0123076. PubMed ID: 25881233
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
    Nita ME; Tominaga O; Nagawa H; Tsuruo T; Muto T
    Hepatogastroenterology; 1998; 45(24):2117-22. PubMed ID: 9951876
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combined therapy with a thymidylate synthase-inhibiting vector and S-1 has effective antitumor activity against 5-FU-resistant tumors.
    Kadota K; Huang CL; Liu D; Yokomise H; Haba R; Wada H
    Int J Oncol; 2011 Feb; 38(2):355-63. PubMed ID: 21174056
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The transfection of thymidylate synthase antisense suppresses oncogenic properties of a human colon cancer cell line and augments the antitumor effect of fluorouracil.
    Matsuoka K; Tsukuda K; Suda M; Kobayashi K; Ota T; Okita A; Watanabe K; Suzuki E; Murakami M; Doihara H; Shimizu N
    Int J Oncol; 2004 Jan; 24(1):217-22. PubMed ID: 14654960
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: three-gene expression model predicts clinical response.
    Matsuyama R; Togo S; Shimizu D; Momiyama N; Ishikawa T; Ichikawa Y; Endo I; Kunisaki C; Suzuki H; Hayasizaki Y; Shimada H
    Int J Cancer; 2006 Jul; 119(2):406-13. PubMed ID: 16477629
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thymidylate synthase and microsatellite instability in colorectal cancer: implications for disease free survival, treatment response and survival with metastases.
    Bendardaf R; Lamlum H; Ristamäki R; Korkeila E; Syrjänen K; Pyrhönen S
    Acta Oncol; 2008; 47(6):1046-53. PubMed ID: 17943475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MicroRNA-375-3p enhances chemosensitivity to 5-fluorouracil by targeting thymidylate synthase in colorectal cancer.
    Xu F; Ye ML; Zhang YP; Li WJ; Li MT; Wang HZ; Qiu X; Xu Y; Yin JW; Hu Q; Wei WH; Chang Y; Liu L; Zhao Q
    Cancer Sci; 2020 May; 111(5):1528-1541. PubMed ID: 32073706
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lack of correlation between immunohistochemical expression of E2F-1, thymidylate synthase expression and clinical response to 5-fluorouracil in advanced colorectal cancer.
    Belvedere O; Puglisi F; Di Loreto C; Cataldi P; Guglielmi A; Aschele C; Sobrero A
    Ann Oncol; 2004 Jan; 15(1):55-8. PubMed ID: 14679120
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of thymidylate synthase mediates desensitization for 5-fluorouracil of tumor cells.
    Saga Y; Suzuki M; Mizukami H; Kohno T; Takei Y; Fukushima M; Ozawa K
    Int J Cancer; 2003 Sep; 106(3):324-6. PubMed ID: 12845668
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Correlation between chemosensitivity and mRNA expression level of 5-fluorouracil-related metabolic enzymes during liver metastasis of colorectal cancer.
    Okumura K; Shiomi H; Mekata E; Kaizuka M; Endo Y; Kurumi Y; Tani T
    Oncol Rep; 2006 Apr; 15(4):875-82. PubMed ID: 16525674
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells.
    Takagi K; Sowa Y; Cevik OM; Nakanishi R; Sakai T
    Int J Oncol; 2008 May; 32(5):1105-10. PubMed ID: 18425338
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells.
    Kawabata R; Oie S; Oka T; Takahashi M; Kanayama H; Itoh K
    Int J Oncol; 2011 Mar; 38(3):665-76. PubMed ID: 21243325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thymidylate synthase levels: prognostic, predictive, or both?
    Allegra C
    J Clin Oncol; 2002 Apr; 20(7):1711-3. PubMed ID: 11919223
    [No Abstract]   [Full Text] [Related]  

  • 14. Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model.
    Abu Lila AS; Moriyoshi N; Fukushima M; Huang CL; Wada H; Ishida T
    Cancer Lett; 2017 Aug; 400():223-231. PubMed ID: 27838412
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase.
    Milczarek M; Rossowska J; Klopotowska D; Stachowicz M; Kutner A; Wietrzyk J
    J Steroid Biochem Mol Biol; 2019 Jun; 190():139-151. PubMed ID: 30923017
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents.
    Yawata A; Kim SR; Miyajima A; Kubo T; Ishida S; Saito Y; Nakajima Y; Katori N; Matsumoto Y; Fukuoka M; Ohno Y; Ozawa S; Sawada J
    Cancer Chemother Pharmacol; 2005 Nov; 56(5):465-72. PubMed ID: 15918040
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Single nucleotide polymorphism in the 5' tandem repeat sequences of thymidylate synthase gene predicts for response to fluorouracil-based chemotherapy in advanced colorectal cancer patients.
    Marcuello E; Altés A; del Rio E; César A; Menoyo A; Baiget M
    Int J Cancer; 2004 Dec; 112(5):733-7. PubMed ID: 15386371
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.
    Salonga D; Danenberg KD; Johnson M; Metzger R; Groshen S; Tsao-Wei DD; Lenz HJ; Leichman CG; Leichman L; Diasio RB; Danenberg PV
    Clin Cancer Res; 2000 Apr; 6(4):1322-7. PubMed ID: 10778957
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors.
    Johnston PG; Lenz HJ; Leichman CG; Danenberg KD; Allegra CJ; Danenberg PV; Leichman L
    Cancer Res; 1995 Apr; 55(7):1407-12. PubMed ID: 7882343
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intratumoural thymidylate synthase and dihydropyrimidine dehydrogenase activities are good predictors of 5-fluorouracil sensitivity in colorectal cancer.
    Ishibiki Y; Kitajima M; Sakamoto K; Tomiki Y; Sakamoto S; Kamano T
    J Int Med Res; 2003; 31(3):181-7. PubMed ID: 12870370
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.