These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
159 related articles for article (PubMed ID: 25883088)
1. Novel Scaffolds of Cell-Active Histone Demethylase Inhibitors Identified from High-Throughput Screening. Wang W; Marholz LJ; Wang X J Biomol Screen; 2015 Jul; 20(6):821-7. PubMed ID: 25883088 [TBL] [Abstract][Full Text] [Related]
2. Substrate- and cofactor-independent inhibition of histone demethylase KDM4C. Leurs U; Lohse B; Rand KD; Ming S; Riise ES; Cole PA; Kristensen JL; Clausen RP ACS Chem Biol; 2014 Sep; 9(9):2131-8. PubMed ID: 25014588 [TBL] [Abstract][Full Text] [Related]
3. Quantitative analysis of histone demethylase probes using fluorescence polarization. Xu W; Podoll JD; Dong X; Tumber A; Oppermann U; Wang X J Med Chem; 2013 Jun; 56(12):5198-202. PubMed ID: 23725560 [TBL] [Abstract][Full Text] [Related]
4. Enabling lead discovery for histone lysine demethylases by high-throughput RapidFire mass spectrometry. Hutchinson SE; Leveridge MV; Heathcote ML; Francis P; Williams L; Gee M; Munoz-Muriedas J; Leavens B; Shillings A; Jones E; Homes P; Baddeley S; Chung CW; Bridges A; Argyrou A J Biomol Screen; 2012 Jan; 17(1):39-48. PubMed ID: 21859681 [TBL] [Abstract][Full Text] [Related]
5. Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7. Gerken PA; Wolstenhulme JR; Tumber A; Hatch SB; Zhang Y; Müller S; Chandler SA; Mair B; Li F; Nijman SMB; Konietzny R; Szommer T; Yapp C; Fedorov O; Benesch JLP; Vedadi M; Kessler BM; Kawamura A; Brennan PE; Smith MD Angew Chem Int Ed Engl; 2017 Dec; 56(49):15555-15559. PubMed ID: 28976073 [TBL] [Abstract][Full Text] [Related]
6. Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors. Korczynska M; Le DD; Younger N; Gregori-Puigjané E; Tumber A; Krojer T; Velupillai S; Gileadi C; Nowak RP; Iwasa E; Pollock SB; Ortiz Torres I; Oppermann U; Shoichet BK; Fujimori DG J Med Chem; 2016 Feb; 59(4):1580-98. PubMed ID: 26699912 [TBL] [Abstract][Full Text] [Related]
7. Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C). Leurs U; Clausen RP; Kristensen JL; Lohse B Bioorg Med Chem Lett; 2012 Sep; 22(18):5811-3. PubMed ID: 22917519 [TBL] [Abstract][Full Text] [Related]
8. A miniaturized screen for inhibitors of Jumonji histone demethylases. Sakurai M; Rose NR; Schultz L; Quinn AM; Jadhav A; Ng SS; Oppermann U; Schofield CJ; Simeonov A Mol Biosyst; 2010 Feb; 6(2):357-64. PubMed ID: 20094655 [TBL] [Abstract][Full Text] [Related]
9. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Wang L; Chang J; Varghese D; Dellinger M; Kumar S; Best AM; Ruiz J; Bruick R; Peña-Llopis S; Xu J; Babinski DJ; Frantz DE; Brekken RA; Quinn AM; Simeonov A; Easmon J; Martinez ED Nat Commun; 2013; 4():2035. PubMed ID: 23792809 [TBL] [Abstract][Full Text] [Related]
10. Tetrazolylhydrazides as Selective Fragment-Like Inhibitors of the JumonjiC-Domain-Containing Histone Demethylase KDM4A. Rüger N; Roatsch M; Emmrich T; Franz H; Schüle R; Jung M; Link A ChemMedChem; 2015 Nov; 10(11):1875-83. PubMed ID: 26337137 [TBL] [Abstract][Full Text] [Related]
11. Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. King ON; Li XS; Sakurai M; Kawamura A; Rose NR; Ng SS; Quinn AM; Rai G; Mott BT; Beswick P; Klose RJ; Oppermann U; Jadhav A; Heightman TD; Maloney DJ; Schofield CJ; Simeonov A PLoS One; 2010 Nov; 5(11):e15535. PubMed ID: 21124847 [TBL] [Abstract][Full Text] [Related]
12. Hypoxia causes epigenetic gene regulation in macrophages by attenuating Jumonji histone demethylase activity. Tausendschön M; Dehne N; Brüne B Cytokine; 2011 Feb; 53(2):256-62. PubMed ID: 21131212 [TBL] [Abstract][Full Text] [Related]
13. Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor. Kristensen LH; Nielsen AL; Helgstrand C; Lees M; Cloos P; Kastrup JS; Helin K; Olsen L; Gajhede M FEBS J; 2012 Jun; 279(11):1905-14. PubMed ID: 22420752 [TBL] [Abstract][Full Text] [Related]
14. A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases. Luo X; Liu Y; Kubicek S; Myllyharju J; Tumber A; Ng S; Che KH; Podoll J; Heightman TD; Oppermann U; Schreiber SL; Wang X J Am Chem Soc; 2011 Jun; 133(24):9451-6. PubMed ID: 21585201 [TBL] [Abstract][Full Text] [Related]
15. A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening. Wigle TJ; Swinger KK; Campbell JE; Scholle MD; Sherrill J; Admirand EA; Boriack-Sjodin PA; Kuntz KW; Chesworth R; Moyer MP; Scott MP; Copeland RA J Biomol Screen; 2015 Jul; 20(6):810-20. PubMed ID: 25755264 [TBL] [Abstract][Full Text] [Related]
16. Configuration of a high-content imaging platform for hit identification and pharmacological assessment of JMJD3 demethylase enzyme inhibitors. Mulji A; Haslam C; Brown F; Randle R; Karamshi B; Smith J; Eagle R; Munoz-Muriedas J; Taylor J; Sheikh A; Bridges A; Gill K; Jepras R; Smee P; Barker M; Woodrow M; Liddle J; Thomas P; Jones E; Gordon L; Tanner R; Leveridge M; Hutchinson S; Martin M; Brown M; Kruidenier L; Katso R J Biomol Screen; 2012 Jan; 17(1):108-20. PubMed ID: 22223398 [TBL] [Abstract][Full Text] [Related]
17. Identification of a Novel Benzimidazole Pyrazolone Scaffold That Inhibits KDM4 Lysine Demethylases and Reduces Proliferation of Prostate Cancer Cells. Carter DM; Specker E; Przygodda J; Neuenschwander M; von Kries JP; Heinemann U; Nazaré M; Gohlke U SLAS Discov; 2017 Aug; 22(7):801-812. PubMed ID: 28346812 [TBL] [Abstract][Full Text] [Related]
18. A protocol for high-throughput screening of histone lysine demethylase 4 inhibitors using TR-FRET assay. Wu Q; Lin W; Li ZM; Rankovic Z; White SW; Chen T; Yang J STAR Protoc; 2021 Sep; 2(3):100702. PubMed ID: 34485934 [TBL] [Abstract][Full Text] [Related]
19. An high-throughput in vivo screening system to select H3K4-specific histone demethylase inhibitors. Mannironi C; Proietto M; Bufalieri F; Cundari E; Alagia A; Danovska S; Rinaldi T; Famiglini V; Coluccia A; La Regina G; Silvestri R; Negri R PLoS One; 2014; 9(1):e86002. PubMed ID: 24489688 [TBL] [Abstract][Full Text] [Related]
20. High-throughput TR-FRET assays for identifying inhibitors of LSD1 and JMJD2C histone lysine demethylases. Yu V; Fisch T; Long AM; Tang J; Lee JH; Hierl M; Chen H; Yakowec P; Schwandner R; Emkey R J Biomol Screen; 2012 Jan; 17(1):27-38. PubMed ID: 21859682 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]