363 related articles for article (PubMed ID: 25885284)
1. Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101).
Mani J; Vallo S; Rakel S; Antonietti P; Gessler F; Blaheta R; Bartsch G; Michaelis M; Cinatl J; Haferkamp A; Kögel D
BMC Cancer; 2015 Apr; 15():224. PubMed ID: 25885284
[TBL] [Abstract][Full Text] [Related]
2. Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737.
Mani J; Antonietti P; Rakel S; Blaheta R; Bartsch G; Haferkamp A; Kögel D
World J Urol; 2016 Feb; 34(2):197-205. PubMed ID: 26100943
[TBL] [Abstract][Full Text] [Related]
3. A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum.
Lian J; Wu X; He F; Karnak D; Tang W; Meng Y; Xiang D; Ji M; Lawrence TS; Xu L
Cell Death Differ; 2011 Jan; 18(1):60-71. PubMed ID: 20577262
[TBL] [Abstract][Full Text] [Related]
4. The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells.
Gao P; Bauvy C; Souquère S; Tonelli G; Liu L; Zhu Y; Qiao Z; Bakula D; Proikas-Cezanne T; Pierron G; Codogno P; Chen Q; Mehrpour M
J Biol Chem; 2010 Aug; 285(33):25570-81. PubMed ID: 20529838
[TBL] [Abstract][Full Text] [Related]
5. Hypoxia-induced autophagy promotes gemcitabine resistance in human bladder cancer cells through hypoxia-inducible factor 1α activation.
Yang X; Yin H; Zhang Y; Li X; Tong H; Zeng Y; Wang Q; He W
Int J Oncol; 2018 Jul; 53(1):215-224. PubMed ID: 29693166
[TBL] [Abstract][Full Text] [Related]
6. -(-)Gossypol promotes the apoptosis of bladder cancer cells in vitro.
Macoska JA; Adsule S; Tantivejkul K; Wang S; Pienta KJ; Lee CT
Pharmacol Res; 2008; 58(5-6):323-31. PubMed ID: 18840529
[TBL] [Abstract][Full Text] [Related]
7. AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy irrespective of expression levels and the subcellular localization of Bcl-xL and Bcl-2 in MCF7 cells.
Antonietti P; Gessler F; Düssmann H; Reimertz C; Mittelbronn M; Prehn JH; Kögel D
Biochim Biophys Acta; 2016 Apr; 1863(4):499-509. PubMed ID: 26721623
[TBL] [Abstract][Full Text] [Related]
8. The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma.
Voss V; Senft C; Lang V; Ronellenfitsch MW; Steinbach JP; Seifert V; Kögel D
Mol Cancer Res; 2010 Jul; 8(7):1002-16. PubMed ID: 20587533
[TBL] [Abstract][Full Text] [Related]
9. Gemcitabine-Induced Autophagy Protects Human Lung Cancer Cells from Apoptotic Death.
Wu HM; Shao LJ; Jiang ZF; Liu RY
Lung; 2016 Dec; 194(6):959-966. PubMed ID: 27604425
[TBL] [Abstract][Full Text] [Related]
10. BH3-mimetic gossypol-induced autophagic cell death in mutant BRAF melanoma cells with high expression of p21Cip¹.).
Jang GH; Lee M
Life Sci; 2014 Apr; 102(1):41-8. PubMed ID: 24625733
[TBL] [Abstract][Full Text] [Related]
11. The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells.
Lian J; Karnak D; Xu L
Autophagy; 2010 Nov; 6(8):1201-3. PubMed ID: 20930561
[TBL] [Abstract][Full Text] [Related]
12. Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells.
Mazumder S; Choudhary GS; Al-Harbi S; Almasan A
Cancer Res; 2012 Jun; 72(12):3069-79. PubMed ID: 22525702
[TBL] [Abstract][Full Text] [Related]
13. Autophagy inhibition enhances pan-Bcl-2 inhibitor AT-101-induced apoptosis in non-small cell lung cancer.
Mei H; Lin Z; Wang Y; Wu G; Song Y
Neoplasma; 2014; 61(2):186-92. PubMed ID: 24299314
[TBL] [Abstract][Full Text] [Related]
14. Combination therapy with gossypol reveals synergism against gemcitabine resistance in cancer cells with high BCL-2 expression.
Wong FY; Liem N; Xie C; Yan FL; Wong WC; Wang L; Yong WP
PLoS One; 2012; 7(12):e50786. PubMed ID: 23226540
[TBL] [Abstract][Full Text] [Related]
15. Preclinical studies of apogossypolone, a novel pan inhibitor of bcl-2 and mcl-1, synergistically potentiates cytotoxic effect of gemcitabine in pancreatic cancer cells.
Banerjee S; Choi M; Aboukameel A; Wang Z; Mohammad M; Chen J; Yang D; Sarkar FH; Mohammad RM
Pancreas; 2010 Apr; 39(3):323-31. PubMed ID: 19823097
[TBL] [Abstract][Full Text] [Related]
16. BAG3 Overexpression and Cytoprotective Autophagy Mediate Apoptosis Resistance in Chemoresistant Breast Cancer Cells.
Das CK; Linder B; Bonn F; Rothweiler F; Dikic I; Michaelis M; Cinatl J; Mandal M; Kögel D
Neoplasia; 2018 Mar; 20(3):263-279. PubMed ID: 29462756
[TBL] [Abstract][Full Text] [Related]
17. BECN1 and BIM interactions with MCL-1 determine fludarabine resistance in leukemic B cells.
Sharma A; Singh K; Mazumder S; Hill BT; Kalaycio M; Almasan A
Cell Death Dis; 2013 May; 4(5):e628. PubMed ID: 23681223
[TBL] [Abstract][Full Text] [Related]
18. Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL.
Bauer JA; Trask DK; Kumar B; Los G; Castro J; Lee JS; Chen J; Wang S; Bradford CR; Carey TE
Mol Cancer Ther; 2005 Jul; 4(7):1096-104. PubMed ID: 16020667
[TBL] [Abstract][Full Text] [Related]
19. Proapoptotic protein Smac mediates apoptosis in cisplatin-resistant ovarian cancer cells when treated with the anti-tumor agent AT101.
Hu W; Wang F; Tang J; Liu X; Yuan Z; Nie C; Wei Y
J Biol Chem; 2012 Jan; 287(1):68-80. PubMed ID: 22052903
[TBL] [Abstract][Full Text] [Related]
20. Hsp90 inhibitor 17-AAG sensitizes Bcl-2 inhibitor (-)-gossypol by suppressing ERK-mediated protective autophagy and Mcl-1 accumulation in hepatocellular carcinoma cells.
Wang B; Chen L; Ni Z; Dai X; Qin L; Wu Y; Li X; Xu L; Lian J; He F
Exp Cell Res; 2014 Nov; 328(2):379-87. PubMed ID: 25196280
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
