287 related articles for article (PubMed ID: 25888396)
1. Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis.
Kukharsky MS; Quintiero A; Matsumoto T; Matsukawa K; An H; Hashimoto T; Iwatsubo T; Buchman VL; Shelkovnikova TA
Mol Neurodegener; 2015 Apr; 10():20. PubMed ID: 25888396
[TBL] [Abstract][Full Text] [Related]
2. ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles.
An H; Skelt L; Notaro A; Highley JR; Fox AH; La Bella V; Buchman VL; Shelkovnikova TA
Acta Neuropathol Commun; 2019 Jan; 7(1):7. PubMed ID: 30642400
[TBL] [Abstract][Full Text] [Related]
3. Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis.
Couthouis J; Hart MP; Erion R; King OD; Diaz Z; Nakaya T; Ibrahim F; Kim HJ; Mojsilovic-Petrovic J; Panossian S; Kim CE; Frackelton EC; Solski JA; Williams KL; Clay-Falcone D; Elman L; McCluskey L; Greene R; Hakonarson H; Kalb RG; Lee VM; Trojanowski JQ; Nicholson GA; Blair IP; Bonini NM; Van Deerlin VM; Mourelatos Z; Shorter J; Gitler AD
Hum Mol Genet; 2012 Jul; 21(13):2899-911. PubMed ID: 22454397
[TBL] [Abstract][Full Text] [Related]
4. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis.
Nishimoto Y; Nakagawa S; Hirose T; Okano HJ; Takao M; Shibata S; Suyama S; Kuwako K; Imai T; Murayama S; Suzuki N; Okano H
Mol Brain; 2013 Jul; 6():31. PubMed ID: 23835137
[TBL] [Abstract][Full Text] [Related]
5. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.
Verbeeck C; Deng Q; Dejesus-Hernandez M; Taylor G; Ceballos-Diaz C; Kocerha J; Golde T; Das P; Rademakers R; Dickson DW; Kukar T
Mol Neurodegener; 2012 Oct; 7():53. PubMed ID: 23046583
[TBL] [Abstract][Full Text] [Related]
6. Compromised paraspeckle formation as a pathogenic factor in FUSopathies.
Shelkovnikova TA; Robinson HK; Troakes C; Ninkina N; Buchman VL
Hum Mol Genet; 2014 May; 23(9):2298-312. PubMed ID: 24334610
[TBL] [Abstract][Full Text] [Related]
7. Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.
Finelli MJ; Liu KX; Wu Y; Oliver PL; Davies KE
Hum Mol Genet; 2015 Jun; 24(12):3529-44. PubMed ID: 25792726
[TBL] [Abstract][Full Text] [Related]
8. Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways.
Blokhuis AM; Koppers M; Groen EJN; van den Heuvel DMA; Dini Modigliani S; Anink JJ; Fumoto K; van Diggelen F; Snelting A; Sodaar P; Verheijen BM; Demmers JAA; Veldink JH; Aronica E; Bozzoni I; den Hertog J; van den Berg LH; Pasterkamp RJ
Acta Neuropathol; 2016 Aug; 132(2):175-196. PubMed ID: 27164932
[TBL] [Abstract][Full Text] [Related]
9. Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.
Wächter N; Storch A; Hermann A
Amyotroph Lateral Scler Frontotemporal Degener; 2015; 16(7-8):431-41. PubMed ID: 26174443
[TBL] [Abstract][Full Text] [Related]
10. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
[TBL] [Abstract][Full Text] [Related]
11. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
[TBL] [Abstract][Full Text] [Related]
12. RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
Daigle JG; Lanson NA; Smith RB; Casci I; Maltare A; Monaghan J; Nichols CD; Kryndushkin D; Shewmaker F; Pandey UB
Hum Mol Genet; 2013 Mar; 22(6):1193-205. PubMed ID: 23257289
[TBL] [Abstract][Full Text] [Related]
13. Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations.
Tradewell ML; Yu Z; Tibshirani M; Boulanger MC; Durham HD; Richard S
Hum Mol Genet; 2012 Jan; 21(1):136-49. PubMed ID: 21965298
[TBL] [Abstract][Full Text] [Related]
14. Rapid in vitro quantification of TDP-43 and FUS mislocalisation for screening of gene variants implicated in frontotemporal dementia and amyotrophic lateral sclerosis.
Oyston LJ; Ubiparipovic S; Fitzpatrick L; Hallupp M; Boccanfuso LM; Kwok JB; Dobson-Stone C
Sci Rep; 2021 Jul; 11(1):14881. PubMed ID: 34290285
[TBL] [Abstract][Full Text] [Related]
15. Aggregation of ALS-linked FUS mutant sequesters RNA binding proteins and impairs RNA granules formation.
Takanashi K; Yamaguchi A
Biochem Biophys Res Commun; 2014 Sep; 452(3):600-7. PubMed ID: 25173930
[TBL] [Abstract][Full Text] [Related]
16. Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies.
Park S; Park SK; Watanabe N; Hashimoto T; Iwatsubo T; Shelkovnikova TA; Liebman SW
PLoS Genet; 2019 Aug; 15(8):e1008308. PubMed ID: 31390360
[TBL] [Abstract][Full Text] [Related]
17. Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis.
Tibshirani M; Zhao B; Gentil BJ; Minotti S; Marques C; Keith J; Rogaeva E; Zinman L; Rouaux C; Robertson J; Durham HD
Hum Mol Genet; 2017 Nov; 26(21):4142-4152. PubMed ID: 28973294
[TBL] [Abstract][Full Text] [Related]
18. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis.
De Santis R; Alfano V; de Turris V; Colantoni A; Santini L; Garone MG; Antonacci G; Peruzzi G; Sudria-Lopez E; Wyler E; Anink JJ; Aronica E; Landthaler M; Pasterkamp RJ; Bozzoni I; Rosa A
Cell Rep; 2019 Jun; 27(13):3818-3831.e5. PubMed ID: 31242416
[TBL] [Abstract][Full Text] [Related]
19. Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.
Kapeli K; Pratt GA; Vu AQ; Hutt KR; Martinez FJ; Sundararaman B; Batra R; Freese P; Lambert NJ; Huelga SC; Chun SJ; Liang TY; Chang J; Donohue JP; Shiue L; Zhang J; Zhu H; Cambi F; Kasarskis E; Hoon S; Ares M; Burge CB; Ravits J; Rigo F; Yeo GW
Nat Commun; 2016 Jul; 7():12143. PubMed ID: 27378374
[TBL] [Abstract][Full Text] [Related]
20. Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
Daigle JG; Krishnamurthy K; Ramesh N; Casci I; Monaghan J; McAvoy K; Godfrey EW; Daniel DC; Johnson EM; Monahan Z; Shewmaker F; Pasinelli P; Pandey UB
Acta Neuropathol; 2016 Apr; 131(4):605-20. PubMed ID: 26728149
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
