246 related articles for article (PubMed ID: 25891774)
1. Structure-activity relationship studies of functionally selective kappa opioid receptor agonists that modulate ERK 1/2 phosphorylation while preserving G protein over βarrestin2 signaling bias.
Lovell KM; Frankowski KJ; Stahl EL; Slauson SR; Yoo E; Prisinzano TE; Aubé J; Bohn LM
ACS Chem Neurosci; 2015 Aug; 6(8):1411-9. PubMed ID: 25891774
[TBL] [Abstract][Full Text] [Related]
2. Development of functionally selective, small molecule agonists at kappa opioid receptors.
Zhou L; Lovell KM; Frankowski KJ; Slauson SR; Phillips AM; Streicher JM; Stahl E; Schmid CL; Hodder P; Madoux F; Cameron MD; Prisinzano TE; Aubé J; Bohn LM
J Biol Chem; 2013 Dec; 288(51):36703-16. PubMed ID: 24187130
[TBL] [Abstract][Full Text] [Related]
3. Identification of novel functionally selective κ-opioid receptor scaffolds.
White KL; Scopton AP; Rives ML; Bikbulatov RV; Polepally PR; Brown PJ; Kenakin T; Javitch JA; Zjawiony JK; Roth BL
Mol Pharmacol; 2014 Jan; 85(1):83-90. PubMed ID: 24113749
[TBL] [Abstract][Full Text] [Related]
4. Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus.
Morgenweck J; Frankowski KJ; Prisinzano TE; Aubé J; Bohn LM
Neuropharmacology; 2015 Dec; 99():600-9. PubMed ID: 26318102
[TBL] [Abstract][Full Text] [Related]
5. Noribogaine is a G-protein biased κ-opioid receptor agonist.
Maillet EL; Milon N; Heghinian MD; Fishback J; Schürer SC; Garamszegi N; Mash DC
Neuropharmacology; 2015 Dec; 99():675-88. PubMed ID: 26302653
[TBL] [Abstract][Full Text] [Related]
6. Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses.
Dunn AD; Reed B; Erazo J; Ben-Ezra A; Kreek MJ
ACS Chem Neurosci; 2019 Aug; 10(8):3590-3600. PubMed ID: 31313902
[TBL] [Abstract][Full Text] [Related]
7. Characterization of kappa opioid receptor mediated, dynorphin-stimulated [35S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting.
Zhou L; Stahl EL; Lovell KM; Frankowski KJ; Prisinzano TE; Aubé J; Bohn LM
Neuropharmacology; 2015 Dec; 99():131-41. PubMed ID: 26160155
[TBL] [Abstract][Full Text] [Related]
8. Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor.
Schattauer SS; Kuhar JR; Song A; Chavkin C
Cell Signal; 2017 Apr; 32():59-65. PubMed ID: 28088389
[TBL] [Abstract][Full Text] [Related]
9. G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons.
Ho JH; Stahl EL; Schmid CL; Scarry SM; Aubé J; Bohn LM
Sci Signal; 2018 Aug; 11(542):. PubMed ID: 30087177
[TBL] [Abstract][Full Text] [Related]
10. The G protein-biased κ-opioid receptor agonist RB-64 is analgesic with a unique spectrum of activities in vivo.
White KL; Robinson JE; Zhu H; DiBerto JF; Polepally PR; Zjawiony JK; Nichols DE; Malanga CJ; Roth BL
J Pharmacol Exp Ther; 2015 Jan; 352(1):98-109. PubMed ID: 25320048
[TBL] [Abstract][Full Text] [Related]
11. Structurally Related Kappa Opioid Receptor Agonists with Substantial Differential Signaling Bias: Neuroendocrine and Behavioral Effects in C57BL6 Mice.
Dunn AD; Reed B; Guariglia C; Dunn AM; Hillman JM; Kreek MJ
Int J Neuropsychopharmacol; 2018 Sep; 21(9):847-857. PubMed ID: 29635340
[TBL] [Abstract][Full Text] [Related]
12. Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons.
Schmid CL; Streicher JM; Groer CE; Munro TA; Zhou L; Bohn LM
J Biol Chem; 2013 Aug; 288(31):22387-98. PubMed ID: 23775075
[TBL] [Abstract][Full Text] [Related]
13. Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on beta-arrestin translocation or receptor endocytosis.
Gripentrog JM; Miettinen HM
Cell Signal; 2005 Oct; 17(10):1300-11. PubMed ID: 16038804
[TBL] [Abstract][Full Text] [Related]
14. Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways.
McLennan GP; Kiss A; Miyatake M; Belcheva MM; Chambers KT; Pozek JJ; Mohabbat Y; Moyer RA; Bohn LM; Coscia CJ
J Neurochem; 2008 Dec; 107(6):1753-65. PubMed ID: 19014370
[TBL] [Abstract][Full Text] [Related]
15. Ligand directed signaling differences between rodent and human κ-opioid receptors.
Schattauer SS; Miyatake M; Shankar H; Zietz C; Levin JR; Liu-Chen LY; Gurevich VV; Rieder MJ; Chavkin C
J Biol Chem; 2012 Dec; 287(50):41595-607. PubMed ID: 23086943
[TBL] [Abstract][Full Text] [Related]
16. Agonist-dependent desensitization of the kappa opioid receptor by G protein receptor kinase and beta-arrestin.
Appleyard SM; Celver J; Pineda V; Kovoor A; Wayman GA; Chavkin C
J Biol Chem; 1999 Aug; 274(34):23802-7. PubMed ID: 10446141
[TBL] [Abstract][Full Text] [Related]
17. The orexin 1 receptor modulates kappa opioid receptor function via a JNK-dependent mechanism.
Robinson JD; McDonald PH
Cell Signal; 2015 Jul; 27(7):1449-56. PubMed ID: 25857454
[TBL] [Abstract][Full Text] [Related]
18. Molecular Interaction Between Butorphanol and κ-Opioid Receptor.
Ji J; Lin W; Vrudhula A; Xi J; Yeliseev A; Grothusen JR; Bu W; Liu R
Anesth Analg; 2020 Sep; 131(3):935-942. PubMed ID: 32701545
[TBL] [Abstract][Full Text] [Related]
19. Intrinsic relative activities of κ opioid agonists in activating Gα proteins and internalizing receptor: Differences between human and mouse receptors.
DiMattio KM; Ehlert FJ; Liu-Chen LY
Eur J Pharmacol; 2015 Aug; 761():235-44. PubMed ID: 26057692
[TBL] [Abstract][Full Text] [Related]
20. beta-Arrestin recruitment assay for the identification of agonists of the sphingosine 1-phosphate receptor EDG1.
van Der Lee MM; Bras M; van Koppen CJ; Zaman GJ
J Biomol Screen; 2008 Dec; 13(10):986-98. PubMed ID: 19036707
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
