These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

339 related articles for article (PubMed ID: 25893378)

  • 1. MTH1 expression is required for effective transformation by oncogenic HRAS.
    Giribaldi MG; Munoz A; Halvorsen K; Patel A; Rai P
    Oncotarget; 2015 May; 6(13):11519-29. PubMed ID: 25893378
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways.
    Patel A; Burton DG; Halvorsen K; Balkan W; Reiner T; Perez-Stable C; Cohen A; Munoz A; Giribaldi MG; Singh S; Robbins DJ; Nguyen DM; Rai P
    Oncogene; 2015 May; 34(20):2586-96. PubMed ID: 25023700
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human Mut T Homolog 1 (MTH1): a roadblock for the tumor-suppressive effects of oncogenic RAS-induced ROS.
    Rai P
    Small GTPases; 2012; 3(2):120-5. PubMed ID: 22790201
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence.
    Rai P; Young JJ; Burton DG; Giribaldi MG; Onder TT; Weinberg RA
    Oncogene; 2011 Mar; 30(12):1489-96. PubMed ID: 21076467
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good?
    Abbas HHK; Alhamoudi KMH; Evans MD; Jones GDD; Foster SS
    BMC Cancer; 2018 Apr; 18(1):423. PubMed ID: 29661172
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Association of MTH1 expression with the tumor malignant potential and poor prognosis in patients with resected lung cancer.
    Fujishita T; Okamoto T; Akamine T; Takamori S; Takada K; Katsura M; Toyokawa G; Shoji F; Shimokawa M; Oda Y; Nakabeppu Y; Maehara Y
    Lung Cancer; 2017 Jul; 109():52-57. PubMed ID: 28577950
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue.
    McPherson LA; Troccoli CI; Ji D; Bowles AE; Gardiner ML; Mohsen MG; Nagathihalli NS; Nguyen DM; Robbins DJ; Merchant NB; Kool ET; Rai P; Ford JM
    DNA Repair (Amst); 2019 Nov; 83():102644. PubMed ID: 31311767
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence.
    Volonte D; Vyas AR; Chen C; Dacic S; Stabile LP; Kurland BF; Abberbock SR; Burns TF; Herman JG; Di YP; Galbiati F
    J Biol Chem; 2018 Feb; 293(5):1794-1809. PubMed ID: 29247004
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The high expression of MTH1 and NUDT5 promotes tumor metastasis and indicates a poor prognosis in patients with non-small-cell lung cancer.
    Li DN; Yang CC; Li J; Ou Yang QG; Zeng LT; Fan GQ; Liu TH; Tian XY; Wang JJ; Zhang H; Dai DP; Cui J; Cai JP
    Biochim Biophys Acta Mol Cell Res; 2021 Jan; 1868(1):118895. PubMed ID: 33096144
    [TBL] [Abstract][Full Text] [Related]  

  • 10. (S)-crizotinib induces apoptosis in human non-small cell lung cancer cells by activating ROS independent of MTH1.
    Dai X; Guo G; Zou P; Cui R; Chen W; Chen X; Yin C; He W; Vinothkumar R; Yang F; Zhang X; Liang G
    J Exp Clin Cancer Res; 2017 Sep; 36(1):120. PubMed ID: 28882182
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impact of Nrf2 on tumour growth and drug sensitivity in oncogenic K-ras-transformed cells in vitro and in vivo.
    Shao J; Glorieux C; Liao J; Chen P; Lu W; Liang Z; Wen S; Hu Y; Huang P
    Free Radic Res; 2018 Jun; 52(6):661-671. PubMed ID: 29621903
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation.
    Kim MJ; Woo SJ; Yoon CH; Lee JS; An S; Choi YH; Hwang SG; Yoon G; Lee SJ
    J Biol Chem; 2011 Apr; 286(15):12924-32. PubMed ID: 21300795
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.
    Lim JKM; Delaidelli A; Minaker SW; Zhang HF; Colovic M; Yang H; Negri GL; von Karstedt S; Lockwood WW; Schaffer P; Leprivier G; Sorensen PH
    Proc Natl Acad Sci U S A; 2019 May; 116(19):9433-9442. PubMed ID: 31000598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
    Huber KV; Salah E; Radic B; Gridling M; Elkins JM; Stukalov A; Jemth AS; Göktürk C; Sanjiv K; Strömberg K; Pham T; Berglund UW; Colinge J; Bennett KL; Loizou JI; Helleday T; Knapp S; Superti-Furga G
    Nature; 2014 Apr; 508(7495):222-7. PubMed ID: 24695225
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Barriers to horizontal cell transformation by extracellular vesicles containing oncogenic H-ras.
    Lee TH; Chennakrishnaiah S; Meehan B; Montermini L; Garnier D; D'Asti E; Hou W; Magnus N; Gayden T; Jabado N; Eppert K; Majewska L; Rak J
    Oncotarget; 2016 Aug; 7(32):51991-52002. PubMed ID: 27437771
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
    Hermann PC; Sancho P; Cañamero M; Martinelli P; Madriles F; Michl P; Gress T; de Pascual R; Gandia L; Guerra C; Barbacid M; Wagner M; Vieira CR; Aicher A; Real FX; Sainz B; Heeschen C
    Gastroenterology; 2014 Nov; 147(5):1119-33.e4. PubMed ID: 25127677
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prognostic impact of MutT homolog-1 expression on esophageal squamous cell carcinoma.
    Akiyama S; Saeki H; Nakashima Y; Iimori M; Kitao H; Oki E; Oda Y; Nakabeppu Y; Kakeji Y; Maehara Y
    Cancer Med; 2017 Jan; 6(1):258-266. PubMed ID: 27917618
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.
    Sato M; Larsen JE; Lee W; Sun H; Shames DS; Dalvi MP; Ramirez RD; Tang H; DiMaio JM; Gao B; Xie Y; Wistuba II; Gazdar AF; Shay JW; Minna JD
    Mol Cancer Res; 2013 Jun; 11(6):638-50. PubMed ID: 23449933
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oncogenic RAS isoforms show a hierarchical requirement for the guanine nucleotide exchange factor SOS2 to mediate cell transformation.
    Sheffels E; Sealover NE; Wang C; Kim DH; Vazirani IA; Lee E; M Terrell E; Morrison DK; Luo J; Kortum RL
    Sci Signal; 2018 Sep; 11(546):. PubMed ID: 30181243
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Investigation of micronucleus induction in MTH1 knockdown cells exposed to UVA, UVB or UVC.
    Fotouhi A; Cornella N; Ramezani M; Wojcik A; Haghdoost S
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Nov; 793():161-5. PubMed ID: 26520386
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.